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The map label for this gene is lspA

Identifier: 41407348

GI number: 41407348

Start: 1330957

End: 1331511

Strand: Direct

Name: lspA

Synonym: MAP1250

Alternate gene names: 41407348

Gene position: 1330957-1331511 (Clockwise)

Preceding gene: 41407346

Following gene: 41407349

Centisome position: 27.56

GC content: 69.01

Gene sequence:

>555_bases
ATGAGCGTGCCTGAACAACCAACGGGATCGACCGCGCCGCACGACCGGCCGCCGCGACGGCTGCGTCTGCTGCTGTCGGT
CGCCGCGACAGTCCTGGCCCTGGACATCGTCACCAAGGTGCTGGCCGTCAAGCTGTTGCCGCCCGGTCAGCCGGTGCCGA
TCATCGGCGACACGGTGACCTGGACCCTGGTTCGCAACTCCGGGGCCGCCTTCTCGATGGCGACCGGCTACACCTGGGTG
CTGACCCTGATCGCGACCGGCGTGGTGGTCGGCATCTTCTGGATGGGACGACGGTTGGTGTCGCCCTGGTGGGCGGTGGG
CCTGGGCATGATCCTGGGCGGCGCGATGGGCAACCTGGTCGACCGCTTCTTCCGGGCCCCCGGGCCGCTGCGCGGCCACG
TGGTGGACTTCCTGTCGGTCGGCTGGTGGCCGGTGTTCAACGTCGCCGACCCCTCGGTGGTCGGCGGGGCCATCCTGCTG
GTCGTGCTGTCGATCTTCGGCTACGACTTCGACACCGTCGGTCGACGGAAAAAGGCCGACCAGAGCCGTGACTGA

Upstream 100 bases:

>100_bases
GTGCCCCCGGTGGCGATCACGGTGAGGCGGGCCATGGGGGAATCATCGCGCATCGCCGCCGCCCGCACGTCGCCGGTCTA
CGGACGCGGTAGGGGATGAT

Downstream 100 bases:

>100_bases
GCGCTCGATGCCGGTCCCGGAGGGACTGGCGGGCATGCGCGTCGACGCCGGGCTGGCCCGCCTGCTGGGACTGTCCCGCA
GCGCGGCGGCGGCCCTGGCC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSVPEQPTGSTAPHDRPPRRLRLLLSVAATVLALDIVTKVLAVKLLPPGQPVPIIGDTVTWTLVRNSGAAFSMATGYTWV
LTLIATGVVVGIFWMGRRLVSPWWAVGLGMILGGAMGNLVDRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILL
VVLSIFGYDFDTVGRRKKADQSRD

Sequences:

>Translated_184_residues
MSVPEQPTGSTAPHDRPPRRLRLLLSVAATVLALDIVTKVLAVKLLPPGQPVPIIGDTVTWTLVRNSGAAFSMATGYTWV
LTLIATGVVVGIFWMGRRLVSPWWAVGLGMILGGAMGNLVDRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILL
VVLSIFGYDFDTVGRRKKADQSRD
>Mature_183_residues
SVPEQPTGSTAPHDRPPRRLRLLLSVAATVLALDIVTKVLAVKLLPPGQPVPIIGDTVTWTLVRNSGAAFSMATGYTWVL
TLIATGVVVGIFWMGRRLVSPWWAVGLGMILGGAMGNLVDRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLV
VLSIFGYDFDTVGRRKKADQSRD

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19816; Mature: 19684

Theoretical pI: Translated: 11.11; Mature: 11.11

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPEQPTGSTAPHDRPPRRLRLLLSVAATVLALDIVTKVLAVKLLPPGQPVPIIGDTVT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCEE
WTLVRNSGAAFSMATGYTWVLTLIATGVVVGIFWMGRRLVSPWWAVGLGMILGGAMGNLV
EEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
DRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVVLSIFGYDFDTVGRRKKAD
HHHHHCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHCCC
QSRD
CCCC
>Mature Secondary Structure 
SVPEQPTGSTAPHDRPPRRLRLLLSVAATVLALDIVTKVLAVKLLPPGQPVPIIGDTVT
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCEE
WTLVRNSGAAFSMATGYTWVLTLIATGVVVGIFWMGRRLVSPWWAVGLGMILGGAMGNLV
EEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
DRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVVLSIFGYDFDTVGRRKKAD
HHHHHCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHCCC
QSRD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA