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The map label for this gene is argK [C]

Identifier: 41407325

GI number: 41407325

Start: 1287771

End: 1288751

Strand: Direct

Name: argK [C]

Synonym: MAP1227

Alternate gene names: 41407325

Gene position: 1287771-1288751 (Clockwise)

Preceding gene: 41407324

Following gene: 41407326

Centisome position: 26.66

GC content: 70.64

Gene sequence:

>981_bases
ATGAGCGGGCGGACGGTGACCGAGCTCGCCGCGGCGATCCGCAGCGGTGACCGCGCGGCGCTGCCGCGCGCCATCACGCT
GTTGGAGTCCACCCGCGCCGACCATCAGGAGCAGGCCCAGCAGCTGTTGTTGGAGCTGACGCCGGATGCCGGCGACGCGC
ATCGAGTCGGCATCACCGGCATCCCCGGGGTGGGCAAGTCCACCAGCATCGAGGCGCTCGGCATGCACCTGATCGGGCTC
GGCCACAAGGTGGCGGTGCTGGCCGTCGACCCGTCGTCGACCCGCACCGGTGGCTCCATCCTGGGCGACAAGACCCGGAT
GGCCCGGCTGGCCAATCATCCGGACGCCTACATCCGGCCATCGCCGACGTCGGGCACGCTGGGCGGCGTGGCCAAGGCCA
CCCGCGAAACGGTGGTCCTGCTCGAGGCCACGGGTTTCGACGTCATCCTGATCGAGACCGTCGGCGTCGGCCAGTCCGAG
GTGACGGTGGCCAACATGGTCGACACGTTCGTGCTGCTGACCCTGGCCCGCGGCGGCGATCAGCTGCAGGGCATCAAGAA
GGGCGTGCTGGAGCTGGCCGACATCGTCGTGGTGAACAAGGCCGACGGCGAGCACCTGGCCGAGGCGCGGTCCGCCGCGC
GTGAACTGTCCGGCGCGATCCGGCTGATCCACCCTCGCGAAACCCTTTGGCGCCCACCGGTTCTCACGATGAGCGCGGCG
CAGGGCACCGGTCTGCCGGAACTGTGGGAGACCATCGAACGGCACCGTCAGGTGCTCAGCAAGGCCGGCGAGTTCGAGGC
GCGGCGCCGGTCGCAATTGGTGGACTGGACCTGGCAGATGGTGCGCGACACGGTGCTGGACCGGCTGCTGTCCAACCCGG
CGGTCCGCACGATGCGCGCCGACGTCGAGCGACGCGTCAAGGCGGGGGAGCTCACCCCGGCGCTGGCTGCCCAGGAAATC
CTGGCGGCCGCGTCGCGCTAA

Upstream 100 bases:

>100_bases
GGGTACGACCTCGGCTGATGGCCGCGATTCCTGCCGCTCTCGTAACGCTACGGCGAAGAATGGCACCGATTTTCGTCATG
GCGTTACAGGCGGCGGTCCC

Downstream 100 bases:

>100_bases
CGGATAGGTAAATAATCCGGATTTCGCTCCTGCCGGGTGTGTAATCCAAGTAGATTCGGAAGTGTGACGGTGGATGCCCG
AGTCGATCGCCGCGCGGTCC

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSGRTVTELAAAIRSGDRAALPRAITLLESTRADHQEQAQQLLLELTPDAGDAHRVGITGIPGVGKSTSIEALGMHLIGL
GHKVAVLAVDPSSTRTGGSILGDKTRMARLANHPDAYIRPSPTSGTLGGVAKATRETVVLLEATGFDVILIETVGVGQSE
VTVANMVDTFVLLTLARGGDQLQGIKKGVLELADIVVVNKADGEHLAEARSAARELSGAIRLIHPRETLWRPPVLTMSAA
QGTGLPELWETIERHRQVLSKAGEFEARRRSQLVDWTWQMVRDTVLDRLLSNPAVRTMRADVERRVKAGELTPALAAQEI
LAAASR

Sequences:

>Translated_326_residues
MSGRTVTELAAAIRSGDRAALPRAITLLESTRADHQEQAQQLLLELTPDAGDAHRVGITGIPGVGKSTSIEALGMHLIGL
GHKVAVLAVDPSSTRTGGSILGDKTRMARLANHPDAYIRPSPTSGTLGGVAKATRETVVLLEATGFDVILIETVGVGQSE
VTVANMVDTFVLLTLARGGDQLQGIKKGVLELADIVVVNKADGEHLAEARSAARELSGAIRLIHPRETLWRPPVLTMSAA
QGTGLPELWETIERHRQVLSKAGEFEARRRSQLVDWTWQMVRDTVLDRLLSNPAVRTMRADVERRVKAGELTPALAAQEI
LAAASR
>Mature_325_residues
SGRTVTELAAAIRSGDRAALPRAITLLESTRADHQEQAQQLLLELTPDAGDAHRVGITGIPGVGKSTSIEALGMHLIGLG
HKVAVLAVDPSSTRTGGSILGDKTRMARLANHPDAYIRPSPTSGTLGGVAKATRETVVLLEATGFDVILIETVGVGQSEV
TVANMVDTFVLLTLARGGDQLQGIKKGVLELADIVVVNKADGEHLAEARSAARELSGAIRLIHPRETLWRPPVLTMSAAQ
GTGLPELWETIERHRQVLSKAGEFEARRRSQLVDWTWQMVRDTVLDRLLSNPAVRTMRADVERRVKAGELTPALAAQEIL
AAASR

Specific function: Probable GTPase. May also bind and hydrolyze ATP. May function as chaperone (Probable) [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=330, Percent_Identity=46.3636363636364, Blast_Score=293, Evalue=2e-79,
Organism=Escherichia coli, GI1789285, Length=309, Percent_Identity=45.3074433656958, Blast_Score=263, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71994271, Length=328, Percent_Identity=40.2439024390244, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71994275, Length=269, Percent_Identity=42.7509293680297, Blast_Score=243, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 34870; Mature: 34739

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRTVTELAAAIRSGDRAALPRAITLLESTRADHQEQAQQLLLELTPDAGDAHRVGITG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEECCCC
IPGVGKSTSIEALGMHLIGLGHKVAVLAVDPSSTRTGGSILGDKTRMARLANHPDAYIRP
CCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHCCHHHHHHHHCCCCCCCCC
SPTSGTLGGVAKATRETVVLLEATGFDVILIETVGVGQSEVTVANMVDTFVLLTLARGGD
CCCCCCCHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCH
QLQGIKKGVLELADIVVVNKADGEHLAEARSAARELSGAIRLIHPRETLWRPPVLTMSAA
HHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCEEEECCHHHHCCCCCEEEECC
QGTGLPELWETIERHRQVLSKAGEFEARRRSQLVDWTWQMVRDTVLDRLLSNPAVRTMRA
CCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
DVERRVKAGELTPALAAQEILAAASR
HHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGRTVTELAAAIRSGDRAALPRAITLLESTRADHQEQAQQLLLELTPDAGDAHRVGITG
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEECCCC
IPGVGKSTSIEALGMHLIGLGHKVAVLAVDPSSTRTGGSILGDKTRMARLANHPDAYIRP
CCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHCCHHHHHHHHCCCCCCCCC
SPTSGTLGGVAKATRETVVLLEATGFDVILIETVGVGQSEVTVANMVDTFVLLTLARGGD
CCCCCCCHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCH
QLQGIKKGVLELADIVVVNKADGEHLAEARSAARELSGAIRLIHPRETLWRPPVLTMSAA
HHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCEEEECCHHHHCCCCCEEEECC
QGTGLPELWETIERHRQVLSKAGEFEARRRSQLVDWTWQMVRDTVLDRLLSNPAVRTMRA
CCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
DVERRVKAGELTPALAAQEILAAASR
HHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]