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The map label for this gene is ruvA

Identifier: 41407135

GI number: 41407135

Start: 1081852

End: 1082451

Strand: Direct

Name: ruvA

Synonym: MAP1037

Alternate gene names: 41407135

Gene position: 1081852-1082451 (Clockwise)

Preceding gene: 41407134

Following gene: 41407136

Centisome position: 22.4

GC content: 75.0

Gene sequence:

>600_bases
ATGATCGCCTCGGTGCGCGGCGAGGTGCTCGAGGTGGCGCTCGACCATGCCGTGATCGAGGCCGCCGGGGTCGGCTACCG
GGTCAACGCGACGCCCTCGACGCTGTCCACGCTGCGCACCGGGACGCAGGCCCGGCTGATCACCGCGATGATCGTCCGCG
AGGATTCGATGACGTTGTACGGCTTCACCGACGCCGAGACCCGTGATTTGTTCCTGACCCTGCTGTCGGTGTCGGGCGTC
GGCCCGCGGCTGGCGATGGCGACGCTGGCCGTGCACGACGCCGGCGCGCTGCGCCAGGCCCTGCACGACGGCGACGTCGC
CGCGCTGACCCGGGTGCCCGGGATCGGCAAGCGCGGCGCCGAGCGGATGGTGCTGGAGCTGCGCGACAAGATCGGCGCGG
CCGGGGCCGCGGGCGCGCCGGCGGGCGCGGCCCGCAACGGCCACGCGGTGCGCGGCCCGGTGGTCGAGGCGCTGGTCGGT
CTCGGCTTCGCCGCCAAGCAGGCCGAGGAGGCCACCGACAAGGTGCTGGCCGCCGAGCCCGAAGCCGGCACCTCCGGCGC
GCTGCGCGCCGCCCTGTCGCTGCTGGGGAAGTCCCGATGA

Upstream 100 bases:

>100_bases
GGGCGCCGATGATCGCCCGGATGGCGCGGGCCGAGGCGCTGGCGGCCCAGCAGCGGCAGAAATACAAGGACAAGGTGGAC
GCGACGCTGAGGGCCGCGCG

Downstream 100 bases:

>100_bases
CCGCCGACGACGATGCAGAGCGAAGCGATGAGGAGGAGCGGCGCAGATGACCGCCCATGACGCCGACTGGTCGGATCGCG
ACGTCTCGGGCGCCCTGGTA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIASVRGEVLEVALDHAVIEAAGVGYRVNATPSTLSTLRTGTQARLITAMIVREDSMTLYGFTDAETRDLFLTLLSVSGV
GPRLAMATLAVHDAGALRQALHDGDVAALTRVPGIGKRGAERMVLELRDKIGAAGAAGAPAGAARNGHAVRGPVVEALVG
LGFAAKQAEEATDKVLAAEPEAGTSGALRAALSLLGKSR

Sequences:

>Translated_199_residues
MIASVRGEVLEVALDHAVIEAAGVGYRVNATPSTLSTLRTGTQARLITAMIVREDSMTLYGFTDAETRDLFLTLLSVSGV
GPRLAMATLAVHDAGALRQALHDGDVAALTRVPGIGKRGAERMVLELRDKIGAAGAAGAPAGAARNGHAVRGPVVEALVG
LGFAAKQAEEATDKVLAAEPEAGTSGALRAALSLLGKSR
>Mature_199_residues
MIASVRGEVLEVALDHAVIEAAGVGYRVNATPSTLSTLRTGTQARLITAMIVREDSMTLYGFTDAETRDLFLTLLSVSGV
GPRLAMATLAVHDAGALRQALHDGDVAALTRVPGIGKRGAERMVLELRDKIGAAGAAGAPAGAARNGHAVRGPVVEALVG
LGFAAKQAEEATDKVLAAEPEAGTSGALRAALSLLGKSR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=34.8258706467662, Blast_Score=110, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_MYCA1 (A0QIB8)

Other databases:

- EMBL:   CP000479
- RefSeq:   YP_882656.1
- ProteinModelPortal:   A0QIB8
- SMR:   A0QIB8
- STRING:   A0QIB8
- EnsemblBacteria:   EBMYCT00000013028
- GeneID:   4526275
- GenomeReviews:   CP000479_GR
- KEGG:   mav:MAV_3474
- TIGR:   MAV_3474
- eggNOG:   COG0632
- GeneTree:   EBGT00050000017612
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   A0QIB8
- ProtClustDB:   PRK00116
- BioCyc:   MAVI243243:MAV_3474-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 20303; Mature: 20303

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASVRGEVLEVALDHAVIEAAGVGYRVNATPSTLSTLRTGTQARLITAMIVREDSMTLY
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHCCCHHHHHHHHEEECCCEEEE
GFTDAETRDLFLTLLSVSGVGPRLAMATLAVHDAGALRQALHDGDVAALTRVPGIGKRGA
EECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCH
ERMVLELRDKIGAAGAAGAPAGAARNGHAVRGPVVEALVGLGFAAKQAEEATDKVLAAEP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHEECCC
EAGTSGALRAALSLLGKSR
CCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIASVRGEVLEVALDHAVIEAAGVGYRVNATPSTLSTLRTGTQARLITAMIVREDSMTLY
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHCCCHHHHHHHHEEECCCEEEE
GFTDAETRDLFLTLLSVSGVGPRLAMATLAVHDAGALRQALHDGDVAALTRVPGIGKRGA
EECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCH
ERMVLELRDKIGAAGAAGAPAGAARNGHAVRGPVVEALVGLGFAAKQAEEATDKVLAAEP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHEECCC
EAGTSGALRAALSLLGKSR
CCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA