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The map label for this gene is mviN

Identifier: 52842841

GI number: 52842841

Start: 2976210

End: 2977781

Strand: Reverse

Name: mviN

Synonym: lpg2635

Alternate gene names: 52842841

Gene position: 2977781-2976210 (Counterclockwise)

Preceding gene: 52842843

Following gene: 52842840

Centisome position: 87.64

GC content: 41.09

Gene sequence:

>1572_bases
ATGCTGACAACGGATATTATGGTACCTAAAAAACAAAGCTTGATACGATCCACTTCCCTTGTTTCATTAATGACATTTAT
TTCAAGGATGGTAGGGTTTGCACGAGATATGGTTCTTGCCAATTTTTTTGGGGCTCAAGCTGGCATGGATGCTTTTTTTG
TTGCTTTCAGGATACCAAATTTTATGCGGCGCCTTTTTGCGGAAGGCGCTTTTTCTCAAGCGTTTGTCCCGGTATTGGCT
GAATATCAAAAAACGCGTTCTGCTGAAGACGTTCGTACTTTCATCGCTCGGATTTCAGGCTATTTGAGTTCTATATTAAC
CCTGGTCACTGTAGTGGGAATTGTAGCATCGCCTGTTATTATTTTTTTATTCGCGCCAGGTTTCCATCATGACAGCGTCC
GGGCTGAATTGGCAACTCAGATGCTTCGTATCACTTTTCCCTATTTAATGCTTATTTCCTTAACAGCAATGGCAGGGGCA
ATATTAAATACCTATGGTTATTTCGGGGTTCCAGCCTTTACTCCCGTTTTGCTTAATATCAGTATGATACTTGCTGCGGT
GTATTTGTGCCCTGATTTGCCACAACCCGTTGTTGGTTTGGCATGGGGTGTGTTGATTGCCGGTATCGTGCAATTGCTTT
TTCAATTACCATTTTTGTATCAACGACATTTGCTTATCAGGCCGAGAGTTGTTCGGGATGATCCAGGAGTCAATAAAGTA
CTCAAGTTAATGATCCCAGCTTTATTTGGCGTTTCAATTGCGCAACTTAACTTGATGATAGATAGTATTTTTGCTTCTTT
TCTAAAGGTAGGGAGTGTCTCTTGGTTATACTATACAGACAGATTAACTGATTTTCCTTTGGGTGTCTTTGGGGTCGCGA
TTGCGACAGTTATCTTGCCCCACCTGTCCCGAAAACACACAGAACAAAATATTAATCAATATTCTCGCGCTTTGGATTGG
GGGCTGCGTTCGATTTTATTAATAGGAATTCCAGCCGGTTTGGGATTGTCCTTTTTTGCCTTGCCTCTGATTGCCAGTTG
TTTTGCTTATGGTAAATTTACTGCCTATGATTTATTACAAACTCAAAAAAGCTTGATTACTCTTGCCATGGGAGTTCCCG
CCTTTATGGTAGTAAAAGTGTTGGCTTCTGGTTTTTATGCTCGTCAGGACATCAGTACCCCTGTAAAAGTGGGTGCCATA
GCCATGGTAGTTAATACTCTTTTATGTTTCATATTTGTCTGGCACTTGGCTCATGCTGGCTTGACATTGGCTTCAGCATT
AGCTGGTTATGTGAATTGTGTTATTTTGCTGTTTCTCTTGATTAAAAGGGGATTGTTCAAACCATCTCCCGGATGGCTGA
AATACAGTATGCAGTTGTTGATAGCCAATTTTGCCATTGGGGTTTATTTATATTTTATGAGTGGAACAGCGACTTACTGG
CTTGGTTTCTCTCCTTTGATGCGTTTGAGCTTGTTATTAGCTCATGTGTTCGTCACCGTAGTCATCTATTTATTAGTTTT
AGGTATAATAGGGCTTAGGCCTAGCCACTTTCGTGGCCAGATAAAGGATTAA

Upstream 100 bases:

>100_bases
CCAGTTTAACCAGATATAAGAGGTATTTCCATGCTTTTTATATCGAACTCGCGCCAGTTTAAGTATATCATAAAGAAAAT
TTTTATCTATTTAAAACATC

Downstream 100 bases:

>100_bases
AAAGATGCAAGCAGAAGTATTTTACAAAAGTTGCGGCGATAGGATAGTTCCTGTCCATCTCATTTCTCAATCACAATGGG
ACGAAGGAATTGAAAATCTA

Product: putative virulence factor MviN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MLTTDIMVPKKQSLIRSTSLVSLMTFISRMVGFARDMVLANFFGAQAGMDAFFVAFRIPNFMRRLFAEGAFSQAFVPVLA
EYQKTRSAEDVRTFIARISGYLSSILTLVTVVGIVASPVIIFLFAPGFHHDSVRAELATQMLRITFPYLMLISLTAMAGA
ILNTYGYFGVPAFTPVLLNISMILAAVYLCPDLPQPVVGLAWGVLIAGIVQLLFQLPFLYQRHLLIRPRVVRDDPGVNKV
LKLMIPALFGVSIAQLNLMIDSIFASFLKVGSVSWLYYTDRLTDFPLGVFGVAIATVILPHLSRKHTEQNINQYSRALDW
GLRSILLIGIPAGLGLSFFALPLIASCFAYGKFTAYDLLQTQKSLITLAMGVPAFMVVKVLASGFYARQDISTPVKVGAI
AMVVNTLLCFIFVWHLAHAGLTLASALAGYVNCVILLFLLIKRGLFKPSPGWLKYSMQLLIANFAIGVYLYFMSGTATYW
LGFSPLMRLSLLLAHVFVTVVIYLLVLGIIGLRPSHFRGQIKD

Sequences:

>Translated_523_residues
MLTTDIMVPKKQSLIRSTSLVSLMTFISRMVGFARDMVLANFFGAQAGMDAFFVAFRIPNFMRRLFAEGAFSQAFVPVLA
EYQKTRSAEDVRTFIARISGYLSSILTLVTVVGIVASPVIIFLFAPGFHHDSVRAELATQMLRITFPYLMLISLTAMAGA
ILNTYGYFGVPAFTPVLLNISMILAAVYLCPDLPQPVVGLAWGVLIAGIVQLLFQLPFLYQRHLLIRPRVVRDDPGVNKV
LKLMIPALFGVSIAQLNLMIDSIFASFLKVGSVSWLYYTDRLTDFPLGVFGVAIATVILPHLSRKHTEQNINQYSRALDW
GLRSILLIGIPAGLGLSFFALPLIASCFAYGKFTAYDLLQTQKSLITLAMGVPAFMVVKVLASGFYARQDISTPVKVGAI
AMVVNTLLCFIFVWHLAHAGLTLASALAGYVNCVILLFLLIKRGLFKPSPGWLKYSMQLLIANFAIGVYLYFMSGTATYW
LGFSPLMRLSLLLAHVFVTVVIYLLVLGIIGLRPSHFRGQIKD
>Mature_523_residues
MLTTDIMVPKKQSLIRSTSLVSLMTFISRMVGFARDMVLANFFGAQAGMDAFFVAFRIPNFMRRLFAEGAFSQAFVPVLA
EYQKTRSAEDVRTFIARISGYLSSILTLVTVVGIVASPVIIFLFAPGFHHDSVRAELATQMLRITFPYLMLISLTAMAGA
ILNTYGYFGVPAFTPVLLNISMILAAVYLCPDLPQPVVGLAWGVLIAGIVQLLFQLPFLYQRHLLIRPRVVRDDPGVNKV
LKLMIPALFGVSIAQLNLMIDSIFASFLKVGSVSWLYYTDRLTDFPLGVFGVAIATVILPHLSRKHTEQNINQYSRALDW
GLRSILLIGIPAGLGLSFFALPLIASCFAYGKFTAYDLLQTQKSLITLAMGVPAFMVVKVLASGFYARQDISTPVKVGAI
AMVVNTLLCFIFVWHLAHAGLTLASALAGYVNCVILLFLLIKRGLFKPSPGWLKYSMQLLIANFAIGVYLYFMSGTATYW
LGFSPLMRLSLLLAHVFVTVVIYLLVLGIIGLRPSHFRGQIKD

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=506, Percent_Identity=45.6521739130435, Blast_Score=451, Evalue=1e-128,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 57702; Mature: 57702

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTDIMVPKKQSLIRSTSLVSLMTFISRMVGFARDMVLANFFGAQAGMDAFFVAFRIPN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
FMRRLFAEGAFSQAFVPVLAEYQKTRSAEDVRTFIARISGYLSSILTLVTVVGIVASPVI
HHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFLFAPGFHHDSVRAELATQMLRITFPYLMLISLTAMAGAILNTYGYFGVPAFTPVLLNI
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SMILAAVYLCPDLPQPVVGLAWGVLIAGIVQLLFQLPFLYQRHLLIRPRVVRDDPGVNKV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHH
LKLMIPALFGVSIAQLNLMIDSIFASFLKVGSVSWLYYTDRLTDFPLGVFGVAIATVILP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
HLSRKHTEQNINQYSRALDWGLRSILLIGIPAGLGLSFFALPLIASCFAYGKFTAYDLLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
TQKSLITLAMGVPAFMVVKVLASGFYARQDISTPVKVGAIAMVVNTLLCFIFVWHLAHAG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LTLASALAGYVNCVILLFLLIKRGLFKPSPGWLKYSMQLLIANFAIGVYLYFMSGTATYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LGFSPLMRLSLLLAHVFVTVVIYLLVLGIIGLRPSHFRGQIKD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8200538; 11677609 [H]