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The map label for this gene is hypE

Identifier: 52842679

GI number: 52842679

Start: 2785466

End: 2786524

Strand: Reverse

Name: hypE

Synonym: lpg2471

Alternate gene names: 52842679

Gene position: 2786524-2785466 (Counterclockwise)

Preceding gene: 52842680

Following gene: 52842678

Centisome position: 82.01

GC content: 44.38

Gene sequence:

>1059_bases
ATGAATGAAATCCTGATAACTAAAAAATTAACGGGGCCAAAGCTGAATTTTAAAGAAGGCACTATCAATTTGACCCATGG
CAGTGGTGGACGTGCTATGGCTCAGCTAATTGAACAATTATTTTTAACCGCATTTGATAATGAATGGTTGGCACAGAAAA
ATGATCAGGCTTGCTTTATTGTTCCTTCAGGACGTATGGTCATGGCAACCGATGCTCATGTTATTTCCCCACTTTTTTTC
CCTGGCGGGGACATTGGTTCTTTGTCAGTGCATGGAACTGTTAATGATGTGGCTATGTCAGGGGCAAAACCTTTGTATTT
GACAGCCAGCTTTATTCTTGAAGAGGGGTTTCCTCTTAAGGATTTGCGAAAAATCGTTTATTCCATGGCTGATGCAGCCA
GGCAAGCAGGTGTTGCCATCATTGCCGGCGATACAAAAGTTGTCGAACGAGGAAAAGGCGATGGTATTTTTATTACGACA
ACCGGAGTAGGGATTGTCCCTGCGGGAATTCATATTTCGGGTGATGCAGCAAAACCCGGTGACAAAATCATTGTGAGCGG
TTTTATAGGGGACCATGGGGTAGCTATTATGGCGCACCGCAATAACCTGGAATTTCAGACCAAAGTGCAGTCTGACACAG
CCTCTTTGCATGGGCTTGTCGGCGAGATGGTGAAAGCAGTTCCAGAACTTCATTGCTTGCGTGATCCAACGCGTGGAGGG
CTTGCAACGACACTGAATGAATTGGCCTTACAATCCAAAGTCGGGTTTGTTATTGATGAAAGTAAAATTCCGATTCGTAC
CGAGGTTGCTAGCGCGTGCGAATTATTAGGTCTTGATCCTCTTTATGTTGCTAATGAAGGAAAATTAATAGCAGTTTGCC
CTTCTGAAAAGGCAGAGAGGCTATTAACTGCTATGAAAGCGCACCCCTTGGGTTTACATGCTGAAATCATTGGTGAGGTG
ATTGAAGATCATCGCTATTTTGTTCAGCTGAAAACAAAATTGGGCGGGTTGCGAATTGTGGATTGGCTGGCCGGAGAGCA
ATTGCCCAGAATCTGTTAA

Upstream 100 bases:

>100_bases
TTGCCAAGGCTTGCTTGCCAGAAAATCCTTTAGGATCCTGTATGGTTTCATCGGAGGGAGCTTGTGCAGCAGTTTATGCT
TATGGACGGGTTAATGCTTT

Downstream 100 bases:

>100_bases
TAAGTAATAACGATCGACAAGAAAGGACGACCAGGATGAACGACAAGAGGAACTGTTTTTTGCCTCATGATAAATTGCAA
CATTTAATTGACTCTTTGCA

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNEILITKKLTGPKLNFKEGTINLTHGSGGRAMAQLIEQLFLTAFDNEWLAQKNDQACFIVPSGRMVMATDAHVISPLFF
PGGDIGSLSVHGTVNDVAMSGAKPLYLTASFILEEGFPLKDLRKIVYSMADAARQAGVAIIAGDTKVVERGKGDGIFITT
TGVGIVPAGIHISGDAAKPGDKIIVSGFIGDHGVAIMAHRNNLEFQTKVQSDTASLHGLVGEMVKAVPELHCLRDPTRGG
LATTLNELALQSKVGFVIDESKIPIRTEVASACELLGLDPLYVANEGKLIAVCPSEKAERLLTAMKAHPLGLHAEIIGEV
IEDHRYFVQLKTKLGGLRIVDWLAGEQLPRIC

Sequences:

>Translated_352_residues
MNEILITKKLTGPKLNFKEGTINLTHGSGGRAMAQLIEQLFLTAFDNEWLAQKNDQACFIVPSGRMVMATDAHVISPLFF
PGGDIGSLSVHGTVNDVAMSGAKPLYLTASFILEEGFPLKDLRKIVYSMADAARQAGVAIIAGDTKVVERGKGDGIFITT
TGVGIVPAGIHISGDAAKPGDKIIVSGFIGDHGVAIMAHRNNLEFQTKVQSDTASLHGLVGEMVKAVPELHCLRDPTRGG
LATTLNELALQSKVGFVIDESKIPIRTEVASACELLGLDPLYVANEGKLIAVCPSEKAERLLTAMKAHPLGLHAEIIGEV
IEDHRYFVQLKTKLGGLRIVDWLAGEQLPRIC
>Mature_352_residues
MNEILITKKLTGPKLNFKEGTINLTHGSGGRAMAQLIEQLFLTAFDNEWLAQKNDQACFIVPSGRMVMATDAHVISPLFF
PGGDIGSLSVHGTVNDVAMSGAKPLYLTASFILEEGFPLKDLRKIVYSMADAARQAGVAIIAGDTKVVERGKGDGIFITT
TGVGIVPAGIHISGDAAKPGDKIIVSGFIGDHGVAIMAHRNNLEFQTKVQSDTASLHGLVGEMVKAVPELHCLRDPTRGG
LATTLNELALQSKVGFVIDESKIPIRTEVASACELLGLDPLYVANEGKLIAVCPSEKAERLLTAMKAHPLGLHAEIIGEV
IEDHRYFVQLKTKLGGLRIVDWLAGEQLPRIC

Specific function: May be involved in the maturation of the nifE hydrogenase [H]

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=46.5875370919881, Blast_Score=298, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 37648; Mature: 37648

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEILITKKLTGPKLNFKEGTINLTHGSGGRAMAQLIEQLFLTAFDNEWLAQKNDQACFI
CCCEEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHCCCCCCEEEE
VPSGRMVMATDAHVISPLFFPGGDIGSLSVHGTVNDVAMSGAKPLYLTASFILEEGFPLK
EECCCEEEEECCHHHCEEECCCCCCCCEEECCCHHHHHHCCCCCEEEEEEHHHHCCCCHH
DLRKIVYSMADAARQAGVAIIAGDTKVVERGKGDGIFITTTGVGIVPAGIHISGDAAKPG
HHHHHHHHHHHHHHHCCEEEEECCHHHHHCCCCCEEEEEECCCCEEECCEEEECCCCCCC
DKIIVSGFIGDHGVAIMAHRNNLEFQTKVQSDTASLHGLVGEMVKAVPELHCLRDPTRGG
CEEEEEEEECCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LATTLNELALQSKVGFVIDESKIPIRTEVASACELLGLDPLYVANEGKLIAVCPSEKAER
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCEEEECCCHHHHH
LLTAMKAHPLGLHAEIIGEVIEDHRYFVQLKTKLGGLRIVDWLAGEQLPRIC
HHHHHHCCCCCCHHHHHHHHHHCCEEEEEEEECCCCEEEEEHHCCCCCCCCC
>Mature Secondary Structure
MNEILITKKLTGPKLNFKEGTINLTHGSGGRAMAQLIEQLFLTAFDNEWLAQKNDQACFI
CCCEEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHCCCCCCEEEE
VPSGRMVMATDAHVISPLFFPGGDIGSLSVHGTVNDVAMSGAKPLYLTASFILEEGFPLK
EECCCEEEEECCHHHCEEECCCCCCCCEEECCCHHHHHHCCCCCEEEEEEHHHHCCCCHH
DLRKIVYSMADAARQAGVAIIAGDTKVVERGKGDGIFITTTGVGIVPAGIHISGDAAKPG
HHHHHHHHHHHHHHHCCEEEEECCHHHHHCCCCCEEEEEECCCCEEECCEEEECCCCCCC
DKIIVSGFIGDHGVAIMAHRNNLEFQTKVQSDTASLHGLVGEMVKAVPELHCLRDPTRGG
CEEEEEEEECCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LATTLNELALQSKVGFVIDESKIPIRTEVASACELLGLDPLYVANEGKLIAVCPSEKAER
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCEEEECCCHHHHH
LLTAMKAHPLGLHAEIIGEVIEDHRYFVQLKTKLGGLRIVDWLAGEQLPRIC
HHHHHHCCCCCCHHHHHHHHHHCCEEEEEEEECCCCEEEEEHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1526470 [H]