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The map label for this gene is hypD

Identifier: 52842680

GI number: 52842680

Start: 2786521

End: 2787627

Strand: Reverse

Name: hypD

Synonym: lpg2472

Alternate gene names: 52842680

Gene position: 2787627-2786521 (Counterclockwise)

Preceding gene: 52842681

Following gene: 52842679

Centisome position: 82.04

GC content: 42.55

Gene sequence:

>1107_bases
GTGAAATACATAGAAGAGTTTCGTAACGGTGCTTACGCACAAGCCATTATCAATGAAATTATCGCAACAGCAGAGCCGCA
AAGACATTATCAGTTTATGGAGTTTTGTGGAGGCCATACTCATGCTATTCATCGTTATGGGATTCCAAGTTTGCTTCCCA
ACAATGTTGAAATGATTCATGGCCCCGGTTGTCCTGTTTGCGTTTTGCCTATAGCGAGAATTGATAAGGCTATTGCGCTT
GCCTCAATGCCGCAAGTGATTCTGTGCAGCTATGCTGACATGCTGCGAGTCCCGGGAAGTGGACAAAAAAGTTTGTTAAC
CGCCAAAGCATGCGGCGCTGATGTCAGGATGATCTATTCTGCGAATGATGCATTAAAAATCGCTCAGGAAAACCCCGATA
AAGACGTTGTGTTTTTTGCTATAGGCTTTGAAACAACAACACCTCCCACTGCTTTTGTCATTAAGCAAGCTAAAAAATTA
AACATCACTAATTTCAGTGTATTTTGTAACCATGTGTTAACTCCCATTGCTATGGATAGTTTGCTGCAGGCCAATGAAGT
TGCCCTGGACGGCTTTGTTGGCCCAGCCCATGTCAGTATCGTGATTGGGAGTTTTCCTTATGAGCAAGTTTGTAAAAAAT
ACCAAAAACCTATCGTGATATCAGGGTTTGAGCCGTTGGATGTGTTGCATTCTATTCTGATGTTAATTCAACAATTGAAT
GAGGGGCGTTGTGATGTGGAAATTCAATACACTCGTGCAGTGAATCGTAAGGGTAATCTTTTGTCACAACGCATCATGGC
CGAAGTCCTGGAAATACGCGATCGTTTTGAATGGCGTGGTTTGGGTTTTATTCCATCCAGCGCATTAAAGATCAAAGAGT
CTTTTTCTGAGTTTGATGCTGAACAGCGTTTCGAATTACCGGAGAGTGCAGCGCAGGAACATAAGCAATGTCTTTGTGGT
GAGGTATTAAGAGGAGTAAAAAAACCAACTGATTGCAAATTATTTGCCAAGGCTTGCTTGCCAGAAAATCCTTTAGGATC
CTGTATGGTTTCATCGGAGGGAGCTTGTGCAGCAGTTTATGCTTATGGACGGGTTAATGCTTTATGA

Upstream 100 bases:

>100_bases
ACGTCATTATTCATGCAGGATTCGCCTTAACAAAACTGGATGAAAGAGAGGCAAACAAAACATTGAGTTTGTTTGCCCAT
ATGCTAAAGGATGGCTTGAA

Downstream 100 bases:

>100_bases
ATGAAATCCTGATAACTAAAAAATTAACGGGGCCAAAGCTGAATTTTAAAGAAGGCACTATCAATTTGACCCATGGCAGT
GGTGGACGTGCTATGGCTCA

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKYIEEFRNGAYAQAIINEIIATAEPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIHGPGCPVCVLPIARIDKAIAL
ASMPQVILCSYADMLRVPGSGQKSLLTAKACGADVRMIYSANDALKIAQENPDKDVVFFAIGFETTTPPTAFVIKQAKKL
NITNFSVFCNHVLTPIAMDSLLQANEVALDGFVGPAHVSIVIGSFPYEQVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
EGRCDVEIQYTRAVNRKGNLLSQRIMAEVLEIRDRFEWRGLGFIPSSALKIKESFSEFDAEQRFELPESAAQEHKQCLCG
EVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVYAYGRVNAL

Sequences:

>Translated_368_residues
MKYIEEFRNGAYAQAIINEIIATAEPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIHGPGCPVCVLPIARIDKAIAL
ASMPQVILCSYADMLRVPGSGQKSLLTAKACGADVRMIYSANDALKIAQENPDKDVVFFAIGFETTTPPTAFVIKQAKKL
NITNFSVFCNHVLTPIAMDSLLQANEVALDGFVGPAHVSIVIGSFPYEQVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
EGRCDVEIQYTRAVNRKGNLLSQRIMAEVLEIRDRFEWRGLGFIPSSALKIKESFSEFDAEQRFELPESAAQEHKQCLCG
EVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVYAYGRVNAL
>Mature_368_residues
MKYIEEFRNGAYAQAIINEIIATAEPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIHGPGCPVCVLPIARIDKAIAL
ASMPQVILCSYADMLRVPGSGQKSLLTAKACGADVRMIYSANDALKIAQENPDKDVVFFAIGFETTTPPTAFVIKQAKKL
NITNFSVFCNHVLTPIAMDSLLQANEVALDGFVGPAHVSIVIGSFPYEQVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
EGRCDVEIQYTRAVNRKGNLLSQRIMAEVLEIRDRFEWRGLGFIPSSALKIKESFSEFDAEQRFELPESAAQEHKQCLCG
EVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVYAYGRVNAL

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=367, Percent_Identity=46.5940054495913, Blast_Score=350, Evalue=1e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 40605; Mature: 40605

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIEEFRNGAYAQAIINEIIATAEPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIH
CCHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEE
GPGCPVCVLPIARIDKAIALASMPQVILCSYADMLRVPGSGQKSLLTAKACGADVRMIYS
CCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHEEEHHHCCCCEEEEEE
ANDALKIAQENPDKDVVFFAIGFETTTPPTAFVIKQAKKLNITNFSVFCNHVLTPIAMDS
CCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLQANEVALDGFVGPAHVSIVIGSFPYEQVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
HHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHC
EGRCDVEIQYTRAVNRKGNLLSQRIMAEVLEIRDRFEWRGLGFIPSSALKIKESFSEFDA
CCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
EQRFELPESAAQEHKQCLCGEVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVY
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEECCCCCEEEEE
AYGRVNAL
ECCCCCCC
>Mature Secondary Structure
MKYIEEFRNGAYAQAIINEIIATAEPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIH
CCHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEE
GPGCPVCVLPIARIDKAIALASMPQVILCSYADMLRVPGSGQKSLLTAKACGADVRMIYS
CCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHEEEHHHCCCCEEEEEE
ANDALKIAQENPDKDVVFFAIGFETTTPPTAFVIKQAKKLNITNFSVFCNHVLTPIAMDS
CCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLQANEVALDGFVGPAHVSIVIGSFPYEQVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
HHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHC
EGRCDVEIQYTRAVNRKGNLLSQRIMAEVLEIRDRFEWRGLGFIPSSALKIKESFSEFDA
CCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
EQRFELPESAAQEHKQCLCGEVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVY
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEECCCCCEEEEE
AYGRVNAL
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8352644; 12948488 [H]