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The map label for this gene is obgE

Identifier: 161723242

GI number: 161723242

Start: 2996850

End: 2997875

Strand: Reverse

Name: obgE

Synonym: lpg2649

Alternate gene names: 161723242

Gene position: 2997875-2996850 (Counterclockwise)

Preceding gene: 52842856

Following gene: 224458591

Centisome position: 88.23

GC content: 43.08

Gene sequence:

>1026_bases
ATGAAATTCGTTGATGAAGCACTTATTAAAGTTGAAGCCGGAAAAGGAGGGAATGGTTGCTTAAGCTTCAGGAGAGAAAA
ATTTATTCCTCGTGGTGGCCCTGACGGGGGTGATGGGGGTGATGGAGGCAGTATTTATTTTGAGGCGAGCAGCGATTTAA
ATACCTTGATTGATTTTCGTTATACTCGTCAATACAAAGCAGAGAATGGACAATCAGGGATGGGTGGAAATTGTACTGGG
AAGAAAGGAGATGATTTAACCATCAAAGTGCCAGTCGGTACTATGGTTTATGATGCTGATACAGGTGAATTGTTAGCTGA
TATCAGTCAACCAGGTATTCCCGTGCTGATTGCTCAGGGTGGGTTTCATGGTTTGGGTAACACTCGCTATAAGAGCAGCG
TGAATCGATCACCTAGACAAACAACACCCGGAAGCCCGGGTGAATCCAGAAATTTGCGTTTGGAGCTCCGAGTTTTGGCA
GACGTAGGTCTGTTAGGGCTTCCCAATGCAGGAAAGTCTACTTTAATAAGAGCCGTCTCCAGTTCAAAAGCCAAAGTGGC
TGACTATCCATTTACAACCTTACATCCAGGTTTAGGGGTGGTCCGTGTTTCACCCTATAAGAGTTTTGTCATGGCGGATA
TCCCAGGTCTTATAGAAGGCGCGGCTCAAGGAGCAGGATTGGGGCATCGGTTTTTAAAACATCTTTCACGTACCTGTGTC
TTGCTGCATGTTATTGATATTGCGCCTTTGGATGGGAGTGATCCTGTCGCTGATGCGAAAGCAATTCTCAATGAGTTGAC
TCAATATAATCCCGATCTGCTCAACAAACCCAGATGGTTGGTTTTAAATAAAATCGATATGTTACCTGATGAAAAGGAAA
GAGAAGAAAAAATTCAATCCATAATAAAAGGCTTGGAGTGGAAAGACAAAGTATTTTCTATTTCCGCTATAGAGAGTAAG
GGAACACAAGAACTTTGCTACGCTTTAATGCAATTGATTGATGAGATGAAAGAGTCTGAAGCTTAG

Upstream 100 bases:

>100_bases
TCAATTCAGTCAATTAGCTTATCTAAGCGCATTCATTGAAAATATTTTTTGCCTTAAGCTTGGAATTTTACGTAAGTCCT
ATTTTAGTCTAAGGTTAGGC

Downstream 100 bases:

>100_bases
CCATTCAGCGGCATAATGCACAACCATAGCACTTCGATAAGGAATCTGATGTGTTTCACGACCCTCTTGCATTTGATTAC
TGTAGTGAATGATTAATTTG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFRYTRQYKAENGQSGMGGNCTG
KKGDDLTIKVPVGTMVYDADTGELLADISQPGIPVLIAQGGFHGLGNTRYKSSVNRSPRQTTPGSPGESRNLRLELRVLA
DVGLLGLPNAGKSTLIRAVSSSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCV
LLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDEKEREEKIQSIIKGLEWKDKVFSISAIESK
GTQELCYALMQLIDEMKESEA

Sequences:

>Translated_341_residues
MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFRYTRQYKAENGQSGMGGNCTG
KKGDDLTIKVPVGTMVYDADTGELLADISQPGIPVLIAQGGFHGLGNTRYKSSVNRSPRQTTPGSPGESRNLRLELRVLA
DVGLLGLPNAGKSTLIRAVSSSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCV
LLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDEKEREEKIQSIIKGLEWKDKVFSISAIESK
GTQELCYALMQLIDEMKESEA
>Mature_341_residues
MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFRYTRQYKAENGQSGMGGNCTG
KKGDDLTIKVPVGTMVYDADTGELLADISQPGIPVLIAQGGFHGLGNTRYKSSVNRSPRQTTPGSPGESRNLRLELRVLA
DVGLLGLPNAGKSTLIRAVSSSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCV
LLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDEKEREEKIQSIIKGLEWKDKVFSISAIESK
GTQELCYALMQLIDEMKESEA

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=338, Percent_Identity=38.1656804733728, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI111955139, Length=305, Percent_Identity=35.0819672131148, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI111955063, Length=208, Percent_Identity=36.0576923076923, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=32.3529411764706, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=38.135593220339, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789574, Length=335, Percent_Identity=63.5820895522388, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1787454, Length=137, Percent_Identity=32.1167883211679, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790615, Length=138, Percent_Identity=34.0579710144928, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=337, Percent_Identity=39.1691394658754, Blast_Score=165, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17552324, Length=330, Percent_Identity=34.2424242424242, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17509631, Length=150, Percent_Identity=34.6666666666667, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6321962, Length=219, Percent_Identity=35.1598173515982, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319281, Length=127, Percent_Identity=36.2204724409449, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321773, Length=164, Percent_Identity=31.0975609756098, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=310, Percent_Identity=39.0322580645161, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24585318, Length=292, Percent_Identity=37.3287671232877, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 36776; Mature: 36776

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFR
CCCHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YTRQYKAENGQSGMGGNCTGKKGDDLTIKVPVGTMVYDADTGELLADISQPGIPVLIAQG
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCHHHHHHHCCCCCEEEEECC
GFHGLGNTRYKSSVNRSPRQTTPGSPGESRNLRLELRVLADVGLLGLPNAGKSTLIRAVS
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEECCCCCHHHHHHHHH
SSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCV
CCCCEECCCCCCEECCCCCEEEECCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHEE
LLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDEKEREEKIQS
EHHHEEECCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCEEEEEHHHCCCCHHHHHHHHHH
IIKGLEWKDKVFSISAIESKGTQELCYALMQLIDEMKESEA
HHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFR
CCCHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YTRQYKAENGQSGMGGNCTGKKGDDLTIKVPVGTMVYDADTGELLADISQPGIPVLIAQG
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCHHHHHHHCCCCCEEEEECC
GFHGLGNTRYKSSVNRSPRQTTPGSPGESRNLRLELRVLADVGLLGLPNAGKSTLIRAVS
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEECCCCCHHHHHHHHH
SSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCV
CCCCEECCCCCCEECCCCCEEEECCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHEE
LLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDEKEREEKIQS
EHHHEEECCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCEEEEEHHHCCCCHHHHHHHHHH
IIKGLEWKDKVFSISAIESKGTQELCYALMQLIDEMKESEA
HHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA