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The map label for this gene is argC

Identifier: 39997965

GI number: 39997965

Start: 3150441

End: 3151481

Strand: Reverse

Name: argC

Synonym: GSU2874

Alternate gene names: 39997965

Gene position: 3151481-3150441 (Counterclockwise)

Preceding gene: 39997966

Following gene: 39997964

Centisome position: 82.63

GC content: 63.21

Gene sequence:

>1041_bases
ATGCTGAAAGTAGCCGTTGTCGGAGCAAGCGGATATACCGGTGTCGAACTTCTGCGCATCCTCCATTGTCACCCGGAGGT
GGCGGTCACCTGCATCACGTCGGAGCAGAGCGCCGGCAAGCCCGTGTCCGACCTGTTTCCGTCCCTGCGGGGGCGCTACG
CCCAGGTGCTGGAAAACCTCGAACCGATCCGGGTGGCGGAGAAAGCGGACATCATCTTCACGGCACTGCCCCACAAGGCG
GCCATGGAAGTGGTTCCTACCTTCCTGAAGCTCGGCAAGCGGGTGATCGACCTGTCGGCCGACTATCGCTTCAACGATGC
CGCCACATACGAGCAATGGTACGAGCCCCACATGAATCCGCACCTCCTGCCCAAGGCGGTCTACGGCCTGCCTGAAGTGC
GCCGGGCTGCCGTCAAGGGTGCCAAGCTCGTGGCCAATCCCGGCTGTTATCCCACAAGCGTGATTCTCGGGCTGCAACCG
CTCCTGAAGCATAAGCTTATCGAAACGGCGGGCATCATCTCCGATTCGGCCTCCGGTGTTTCGGGGGCAGGGCGTGGGGC
CAAGGTGGACAATCTCTACTGCGAGGTCAACGAGGGGTTCAAGGCCTACGGCGTCGGCGGCGTCCATCGCCATACCCCCG
AGATGGAGCAGGAGCTGTCGTTGCTGGCTGATGAGCGGATCACTATCACCTTTACCCCCCACCTTGCTCCCATGGATCGC
GGGATTCTCTCCACCATCTACGGCAGGCTGCTCACTCCCGCCACTACCGCCGAGCTAGCCGGGCTCTATGCCGAGTTCTA
CGGGGGCGAGCCCTTCGTGCGGGTCCTTCCCGCCGGCGGTGTGCCGTCCACCGCCCATGTGCGCGGCTCTAACTTCTGTG
ACATTGGAGTGGTCGTGGATCAGCGTACCGGCAGGGTCATCGTGGTTTCAGCCATCGACAACCTGGTCAAGGGCGCCTCG
GGGCAGGCGGTGCAGAATATGAACATCATGTGCGGGCTGCCCGAAGGGCTCGGCCTGGAGGGGCTGGCGCTCGTCCCCTG
A

Upstream 100 bases:

>100_bases
CCGTTTTCGGATGGACAGAGGGGAAAACCTGCGGGTTTTCCCCTTTTGCGTATTCAGGTTTCCGGTTCATCGTTCATTTC
TCCAGGAAGGGGAGCGTGCC

Downstream 100 bases:

>100_bases
CGGCGCCTTCCGGCCATGTCGTTTCTCCCTGTCACCCGCGGCGAAGCCCTGAAGCGCGGCTGGGACGAGCTGGACATCGT
CTTCGTCACCGGCGACGCCT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MLKVAVVGASGYTGVELLRILHCHPEVAVTCITSEQSAGKPVSDLFPSLRGRYAQVLENLEPIRVAEKADIIFTALPHKA
AMEVVPTFLKLGKRVIDLSADYRFNDAATYEQWYEPHMNPHLLPKAVYGLPEVRRAAVKGAKLVANPGCYPTSVILGLQP
LLKHKLIETAGIISDSASGVSGAGRGAKVDNLYCEVNEGFKAYGVGGVHRHTPEMEQELSLLADERITITFTPHLAPMDR
GILSTIYGRLLTPATTAELAGLYAEFYGGEPFVRVLPAGGVPSTAHVRGSNFCDIGVVVDQRTGRVIVVSAIDNLVKGAS
GQAVQNMNIMCGLPEGLGLEGLALVP

Sequences:

>Translated_346_residues
MLKVAVVGASGYTGVELLRILHCHPEVAVTCITSEQSAGKPVSDLFPSLRGRYAQVLENLEPIRVAEKADIIFTALPHKA
AMEVVPTFLKLGKRVIDLSADYRFNDAATYEQWYEPHMNPHLLPKAVYGLPEVRRAAVKGAKLVANPGCYPTSVILGLQP
LLKHKLIETAGIISDSASGVSGAGRGAKVDNLYCEVNEGFKAYGVGGVHRHTPEMEQELSLLADERITITFTPHLAPMDR
GILSTIYGRLLTPATTAELAGLYAEFYGGEPFVRVLPAGGVPSTAHVRGSNFCDIGVVVDQRTGRVIVVSAIDNLVKGAS
GQAVQNMNIMCGLPEGLGLEGLALVP
>Mature_346_residues
MLKVAVVGASGYTGVELLRILHCHPEVAVTCITSEQSAGKPVSDLFPSLRGRYAQVLENLEPIRVAEKADIIFTALPHKA
AMEVVPTFLKLGKRVIDLSADYRFNDAATYEQWYEPHMNPHLLPKAVYGLPEVRRAAVKGAKLVANPGCYPTSVILGLQP
LLKHKLIETAGIISDSASGVSGAGRGAKVDNLYCEVNEGFKAYGVGGVHRHTPEMEQELSLLADERITITFTPHLAPMDR
GILSTIYGRLLTPATTAELAGLYAEFYGGEPFVRVLPAGGVPSTAHVRGSNFCDIGVVVDQRTGRVIVVSAIDNLVKGAS
GQAVQNMNIMCGLPEGLGLEGLALVP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=345, Percent_Identity=42.0289855072464, Blast_Score=216, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6320913, Length=346, Percent_Identity=30.635838150289, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_GEOSL (Q748X6)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_953916.1
- ProteinModelPortal:   Q748X6
- SMR:   Q748X6
- GeneID:   2688689
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU2874
- NMPDR:   fig|243231.1.peg.2854
- TIGR:   GSU2874
- HOGENOM:   HBG294213
- OMA:   GCFPTAS
- ProtClustDB:   PRK00436
- BioCyc:   GSUL243231:GSU_2874-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 36961; Mature: 36961

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVAVVGASGYTGVELLRILHCHPEVAVTCITSEQSAGKPVSDLFPSLRGRYAQVLENL
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCC
EPIRVAEKADIIFTALPHKAAMEVVPTFLKLGKRVIDLSADYRFNDAATYEQWYEPHMNP
CCEEECCCCCEEEEECCCHHHHHHHHHHHHHCHHEEECCCCCCCCCCCCHHHHHCCCCCC
HLLPKAVYGLPEVRRAAVKGAKLVANPGCYPTSVILGLQPLLKHKLIETAGIISDSASGV
CCCHHHHHCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SGAGRGAKVDNLYCEVNEGFKAYGVGGVHRHTPEMEQELSLLADERITITFTPHLAPMDR
CCCCCCCEECEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHH
GILSTIYGRLLTPATTAELAGLYAEFYGGEPFVRVLPAGGVPSTAHVRGSNFCDIGVVVD
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCEEEEEEEE
QRTGRVIVVSAIDNLVKGASGQAVQNMNIMCGLPEGLGLEGLALVP
CCCCCEEEEEEHHHHHCCCCCCEEECCEEEEECCCCCCCCCEEECC
>Mature Secondary Structure
MLKVAVVGASGYTGVELLRILHCHPEVAVTCITSEQSAGKPVSDLFPSLRGRYAQVLENL
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCC
EPIRVAEKADIIFTALPHKAAMEVVPTFLKLGKRVIDLSADYRFNDAATYEQWYEPHMNP
CCEEECCCCCEEEEECCCHHHHHHHHHHHHHCHHEEECCCCCCCCCCCCHHHHHCCCCCC
HLLPKAVYGLPEVRRAAVKGAKLVANPGCYPTSVILGLQPLLKHKLIETAGIISDSASGV
CCCHHHHHCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SGAGRGAKVDNLYCEVNEGFKAYGVGGVHRHTPEMEQELSLLADERITITFTPHLAPMDR
CCCCCCCEECEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHH
GILSTIYGRLLTPATTAELAGLYAEFYGGEPFVRVLPAGGVPSTAHVRGSNFCDIGVVVD
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCEEEEEEEE
QRTGRVIVVSAIDNLVKGASGQAVQNMNIMCGLPEGLGLEGLALVP
CCCCCEEEEEEHHHHHCCCCCCEEECCEEEEECCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA