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The map label for this gene is cysU [H]

Identifier: 39997795

GI number: 39997795

Start: 2980760

End: 2981446

Strand: Direct

Name: cysU [H]

Synonym: GSU2701

Alternate gene names: 39997795

Gene position: 2980760-2981446 (Clockwise)

Preceding gene: 39997794

Following gene: 39997796

Centisome position: 78.15

GC content: 65.65

Gene sequence:

>687_bases
ATGGACTTTTATTCCGAATCCCTGACGACCGCCCTCCAGCTCATTGCCTCCCGCGACCCGGACGTGGTGAGCGCGGTGAC
CGTGTCGATCGTCGTCTCGCTCTGGTCGACCCTGTTCGCTGCCCTGGCCGGCGTGCCTGCGGGAGTGGCGGTGGCGGTGG
CTGAGTTTCCCGGCAAGCGGGCCGTGGTGACGCTGCTCAACACCCTCATGGCCCTGCCCACGGTGGTGGTGGGACTCTTT
GTCTACAGCCTCATCAGCCGCCAGGGACCCTTGGGCGAATTCGGCCTTCTCTTCACCCCCTGGGCCATGGTCGTGGGTCA
GACGCTCCTGGCCATCCCCATCGTGGCGAACCTGACCATGAGCGCCATCAAGGGTGCCGATCCCCGCATCGTCCCAACGG
CCCTCACCCTGGGCGCCGGGCCGTTCGAAAGTATCCGACGACTGGTACTGGAAATGCGTTTCGGCATCATGGCCGCGCTC
ATTGCCGCCTTTGGCCGGGTCATCGCCGAGGTGGGAGTTGCCATGATGCTCGGCGGCAACATCCGGGGCCATACCCGGAC
CATGACGACCGCCATCGCCATGGAGACCGGCAAGGGGGAATTCGCCCTGGGGCTCGCCCTGGGGCTCATCCTCATGGCGG
TCGCGCTGATCGTCAACATGGCTCTCAACGCCCTGCAGCAGAGGTGA

Upstream 100 bases:

>100_bases
GCCGGTCTTCTTTATTTACAAGAAATAGAAATCATCATAGCATTGAACCGCTGATCGGGGGTATCTGTGACCGGTCAGCG
GTTCGCTTTCATCCGAAGCC

Downstream 100 bases:

>100_bases
CAGCACCATGAGCGAATGCATCCGGCTCACCAACATACGCACTACCTACGCCGGCCGGACCGTCCTTGCCATTGACCGGC
TCACGCTGCGCAGCGGCAGA

Product: ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MDFYSESLTTALQLIASRDPDVVSAVTVSIVVSLWSTLFAALAGVPAGVAVAVAEFPGKRAVVTLLNTLMALPTVVVGLF
VYSLISRQGPLGEFGLLFTPWAMVVGQTLLAIPIVANLTMSAIKGADPRIVPTALTLGAGPFESIRRLVLEMRFGIMAAL
IAAFGRVIAEVGVAMMLGGNIRGHTRTMTTAIAMETGKGEFALGLALGLILMAVALIVNMALNALQQR

Sequences:

>Translated_228_residues
MDFYSESLTTALQLIASRDPDVVSAVTVSIVVSLWSTLFAALAGVPAGVAVAVAEFPGKRAVVTLLNTLMALPTVVVGLF
VYSLISRQGPLGEFGLLFTPWAMVVGQTLLAIPIVANLTMSAIKGADPRIVPTALTLGAGPFESIRRLVLEMRFGIMAAL
IAAFGRVIAEVGVAMMLGGNIRGHTRTMTTAIAMETGKGEFALGLALGLILMAVALIVNMALNALQQR
>Mature_228_residues
MDFYSESLTTALQLIASRDPDVVSAVTVSIVVSLWSTLFAALAGVPAGVAVAVAEFPGKRAVVTLLNTLMALPTVVVGLF
VYSLISRQGPLGEFGLLFTPWAMVVGQTLLAIPIVANLTMSAIKGADPRIVPTALTLGAGPFESIRRLVLEMRFGIMAAL
IAAFGRVIAEVGVAMMLGGNIRGHTRTMTTAIAMETGKGEFALGLALGLILMAVALIVNMALNALQQR

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4662

COG function: function code H; ABC-type tungstate transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=217, Percent_Identity=25.8064516129032, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082099, Length=198, Percent_Identity=25.2525252525253, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011865
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23795; Mature: 23795

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFYSESLTTALQLIASRDPDVVSAVTVSIVVSLWSTLFAALAGVPAGVAVAVAEFPGKR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCH
AVVTLLNTLMALPTVVVGLFVYSLISRQGPLGEFGLLFTPWAMVVGQTLLAIPIVANLTM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIKGADPRIVPTALTLGAGPFESIRRLVLEMRFGIMAALIAAFGRVIAEVGVAMMLGGN
HHHCCCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IRGHTRTMTTAIAMETGKGEFALGLALGLILMAVALIVNMALNALQQR
CCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFYSESLTTALQLIASRDPDVVSAVTVSIVVSLWSTLFAALAGVPAGVAVAVAEFPGKR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCH
AVVTLLNTLMALPTVVVGLFVYSLISRQGPLGEFGLLFTPWAMVVGQTLLAIPIVANLTM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIKGADPRIVPTALTLGAGPFESIRRLVLEMRFGIMAALIAAFGRVIAEVGVAMMLGGN
HHHCCCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IRGHTRTMTTAIAMETGKGEFALGLALGLILMAVALIVNMALNALQQR
CCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2188958; 9205837; 9278503; 2188959 [H]