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The map label for this gene is norM [H]

Identifier: 39997747

GI number: 39997747

Start: 2923302

End: 2924756

Strand: Direct

Name: norM [H]

Synonym: GSU2653

Alternate gene names: 39997747

Gene position: 2923302-2924756 (Clockwise)

Preceding gene: 39997746

Following gene: 39997748

Centisome position: 76.64

GC content: 67.29

Gene sequence:

>1455_bases
ATGTCCCCAAACGGATCAAGGAATGGTACTATTAGCAGGATGAAATCCTCTGTCGACCTGATCCGCGATCCCATCCCGCA
GCTCCTGGTCCGGCTCGCCGTGCCCGTGGGGACCGGCTTTTTCTTCAACACCATGTTCAACGTGGTGGACACCTTCTACG
GCGGCCTCATCTCCACCAAGGCGCTGGCGGCCCTGTCCCTCTCCTTTCCCCTTTTCTTCATCGTCCTGGCCCTGGGGGCG
GGAACCTCCATGGGCGCCACGGCCCTCATCGGCCATGCGCTGGGGAGCGACAACCGCGACGATGCCGAACTCTACGCGGC
CCAGGCGGTTTCCTTCGGGGTGCTCCATGCCCTGCTCCTCACGGCCGTCGGGCTCGCCACGGCACCGGCGGTCTTCCGGC
TCATGGGGGCCTCCGGCGACTACCTGGACCTGGCCCTGGTCTACATGGACGTCCTCTTTGCCGGCAGCATCTTCTTCATG
GGCAACTATATTCTCAACTCCATGCTCAATGCCGCGGGCGACACCAAGAGCTTCCGCAATTTCCTGGTGACGGGCTTTTT
CTTGAACCTGGCCCTGGACCCCTGGTTCATGTATGGCGGCTTCGGCATCCCGGCCATGGGGATCGGCGGCATCGCCCTGG
CCACGGTGATGATCCAGGCCGCGGGCAACCTCTACCTCCTGGGCCGGGTCCGGCGGACCGGGCTCTTGTCAGGACGGTCG
TGGCGACTGATGGCACCGCGGCGGGAGCCGTTCCGGCGGCTCTTCGGCCAGGGATTCCCCGCAAGCCTCAACATGCTGAC
CGTGTCCCTGGGCATCTTCGTGATCACCTGGTTCGCGGGACGGTTCGGGAAAGAAGCGGTGGCCGCCTACGGCATCGGCA
CCCGGATCGAGCAGATCGTGCTCCTGCCGGCCATGGGGCTGAACGTGGCGGTCCTGTCCCTGGTGGCACAGAACTTCGGC
GCGGGAAAGCTGGCGCGGGTGCGGGAAGCACTGTCCCGGGCTCTGCGGGCCGGGCTCCTGATGATGGCCGCCGGGACGGT
ACTGGTGATGGCCACGGCGGCCCCCCTGGTGGGGCTGTTCACCGATGACCCCGCGGTCGTTGCCCGGGGGGCGGGCTTCC
TGCGGGTAGAGGCGCTGGTGCTCGGGGCTTACGTGATCCTGTACGTGAACAACTCGGCCCTCCAGGCGCTCCAGCGCCCC
GCCTTCGCCCTCTGGATCGGGTTGTTCCGCCAGATCCTGGCCCCGGTGCCGGTCTTCTGGCTGCTGGCCCTGCGGCTCGG
CTGGGGACTGCCCGGCATCTGGTGGGGGGTAGCGCTCGTCACCTGGAGCGCGGCGGCCGTTTCCATGCTCTACACCCGCC
GCGTCATGCGCGAACTGGAGGCGGAGGCCGATCTCCTCCTGGCCGCCAACGGCGGGGCACCGGCCGTTTCGGGGCCTCCG
ACCGGCGGGAAATGA

Upstream 100 bases:

>100_bases
CATGAACAGGGGCTCGGATCGATGTGATCCGGGCCCCTGCCTGTTTCGCTACACCGGATTCCGCCGTCACAAGACCAAAA
ATGCCGGAGCCGGCACCGCC

Downstream 100 bases:

>100_bases
TGCGAAACCGGAACGCTCTGGTATCCTTGCTCGTAAACCGGCGATGACGGCCGGGCCGCGACGCCATCAAAGCCCGTGCC
TGCACAACATCATCAACCTG

Product: MATE efflux family protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSPNGSRNGTISRMKSSVDLIRDPIPQLLVRLAVPVGTGFFFNTMFNVVDTFYGGLISTKALAALSLSFPLFFIVLALGA
GTSMGATALIGHALGSDNRDDAELYAAQAVSFGVLHALLLTAVGLATAPAVFRLMGASGDYLDLALVYMDVLFAGSIFFM
GNYILNSMLNAAGDTKSFRNFLVTGFFLNLALDPWFMYGGFGIPAMGIGGIALATVMIQAAGNLYLLGRVRRTGLLSGRS
WRLMAPRREPFRRLFGQGFPASLNMLTVSLGIFVITWFAGRFGKEAVAAYGIGTRIEQIVLLPAMGLNVAVLSLVAQNFG
AGKLARVREALSRALRAGLLMMAAGTVLVMATAAPLVGLFTDDPAVVARGAGFLRVEALVLGAYVILYVNNSALQALQRP
AFALWIGLFRQILAPVPVFWLLALRLGWGLPGIWWGVALVTWSAAAVSMLYTRRVMRELEAEADLLLAANGGAPAVSGPP
TGGK

Sequences:

>Translated_484_residues
MSPNGSRNGTISRMKSSVDLIRDPIPQLLVRLAVPVGTGFFFNTMFNVVDTFYGGLISTKALAALSLSFPLFFIVLALGA
GTSMGATALIGHALGSDNRDDAELYAAQAVSFGVLHALLLTAVGLATAPAVFRLMGASGDYLDLALVYMDVLFAGSIFFM
GNYILNSMLNAAGDTKSFRNFLVTGFFLNLALDPWFMYGGFGIPAMGIGGIALATVMIQAAGNLYLLGRVRRTGLLSGRS
WRLMAPRREPFRRLFGQGFPASLNMLTVSLGIFVITWFAGRFGKEAVAAYGIGTRIEQIVLLPAMGLNVAVLSLVAQNFG
AGKLARVREALSRALRAGLLMMAAGTVLVMATAAPLVGLFTDDPAVVARGAGFLRVEALVLGAYVILYVNNSALQALQRP
AFALWIGLFRQILAPVPVFWLLALRLGWGLPGIWWGVALVTWSAAAVSMLYTRRVMRELEAEADLLLAANGGAPAVSGPP
TGGK
>Mature_483_residues
SPNGSRNGTISRMKSSVDLIRDPIPQLLVRLAVPVGTGFFFNTMFNVVDTFYGGLISTKALAALSLSFPLFFIVLALGAG
TSMGATALIGHALGSDNRDDAELYAAQAVSFGVLHALLLTAVGLATAPAVFRLMGASGDYLDLALVYMDVLFAGSIFFMG
NYILNSMLNAAGDTKSFRNFLVTGFFLNLALDPWFMYGGFGIPAMGIGGIALATVMIQAAGNLYLLGRVRRTGLLSGRSW
RLMAPRREPFRRLFGQGFPASLNMLTVSLGIFVITWFAGRFGKEAVAAYGIGTRIEQIVLLPAMGLNVAVLSLVAQNFGA
GKLARVREALSRALRAGLLMMAAGTVLVMATAAPLVGLFTDDPAVVARGAGFLRVEALVLGAYVILYVNNSALQALQRPA
FALWIGLFRQILAPVPVFWLLALRLGWGLPGIWWGVALVTWSAAAVSMLYTRRVMRELEAEADLLLAANGGAPAVSGPPT
GGK

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=460, Percent_Identity=22.8260869565217, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51338; Mature: 51207

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCC
>Mature Secondary Structure 
SPNGSRNGTISRMKSSVDLIRDPIPQLLVRLAVPVGTGFFFNTMFNVVDTFYGGLISTK
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ALAALSLSFPLFFIVLALGAGTSMGATALIGHALGSDNRDDAELYAAQAVSFGVLHALLL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
TAVGLATAPAVFRLMGASGDYLDLALVYMDVLFAGSIFFMGNYILNSMLNAAGDTKSFRN
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
FLVTGFFLNLALDPWFMYGGFGIPAMGIGGIALATVMIQAAGNLYLLGRVRRTGLLSGRS
HHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCC
WRLMAPRREPFRRLFGQGFPASLNMLTVSLGIFVITWFAGRFGKEAVAAYGIGTRIEQIV
EEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHH
LLPAMGLNVAVLSLVAQNFGAGKLARVREALSRALRAGLLMMAAGTVLVMATAAPLVGLF
HCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
TDDPAVVARGAGFLRVEALVLGAYVILYVNNSALQALQRPAFALWIGLFRQILAPVPVFW
CCCHHHHHCCCCHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALRLGWGLPGIWWGVALVTWSAAAVSMLYTRRVMRELEAEADLLLAANGGAPAVSGPP
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC
TGGK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]