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The map label for this gene is yabD [H]

Identifier: 39997584

GI number: 39997584

Start: 2733951

End: 2735339

Strand: Direct

Name: yabD [H]

Synonym: GSU2489

Alternate gene names: 39997584

Gene position: 2733951-2735339 (Clockwise)

Preceding gene: 39997583

Following gene: 39997585

Centisome position: 71.68

GC content: 67.24

Gene sequence:

>1389_bases
ATGAACGAGTCAGGTTTTCTCATCGACACCCACGCCCATATCGACGGCCACGACTTTGCGGCCGATTTCGACGCCATGCT
CTCCCGCGCCTGGGAGGCGGGGCTTTCCCACATCGTCACGGTAGGGGCTGACCTGGAGTCCAGCCGGGCCGCAGTGGCAC
TGGCCGGCCGCCACGAGCGGATCTGGTGCGCCGTGGGCATCCATCCCCACGACGCGGGGCGGGTGACCGACCGCTGCTAC
GACGAGATCAGGACCCTGGCCCAGGGGAACCCCAAGGTGGCGGCCATCGGCGAAATCGGGCTCGACTTCTTCCGGGACCG
CTCGCCCCGCGACGAGCAGGAACAGGTCTTCCGCCGCTTCATCAGGCTGGCCCGGGAACTGGCATTGCCCATCGTGGTGC
ACGACCGCGACGCCCACGAGCGGGTCATGGCGATCCTGCGCGAGGAAAAGGCCCGGGACGTGGGTGGCGTGCTCCACTGC
TTCTCCGGCGACCTGGCCATGGCCAGGGAATGCGTGGACATGGGCTTCCTGATCTCCATCCCCGGCACCGTCACCTACCC
TTCCAACGAAGCCCTGCGCGAGGTGGTGCGCGGCGTCAAGATCGAGCACCTGCTGGTGGAGACCGACTGTCCCTACCTCA
CCCCGGTCCCCCACCGCGGGAAGCGGAACGAGCCGGCCTACGTGCGGCTCACCGCCGAAAAAGTGGCGGAACTGAAAGGG
CTCTCCCTGGAGGACGTGGGACGGATCACCTCCCTCAACGCCCGGCGGCTCTTCGGCATCGGGGAGAGCGACCAGGCGGC
CCGGATCGCCTACCGGATCAGGAACTCCCTCTACCTGAACATCACCAACCGCTGCTCAAACCGCTGTTCCTTCTGCGCCA
AGTTCGACGACTACACGGTGAAAGGACACCACCTCCGGCTGGACCACGAGCCGGACAGCGCCGAGGTGCTGGCTGCCGTC
GGTGAGCCGGGGCCGGTGGATGAAATCGTCTTCTGCGGCTTCGGCGAGCCCATGCTCCGCCTCGACCTGATCGTGGAAGT
GGCGCGGGAACTGAAGAAACGCGGCTTCCGCATCCGTATCAACACCGACGGCCAGGCGAACCTGGTCCACGGCCGCAACG
TCCTGCCCGAACTGCAAGGCCTGGTGGACTGCATCTCCGTGAGCCTCAACGCCGCCGACGCCGACACGTACGCCCGCCTC
TGCAACACCCCCTTCGGCACCAACGGCTTCAACGGCATCTGCCGGTTCCTGGAAGAGGCCCGGCTGTACATCCCCACGGT
GGTGGCCACGGCCGTTACCGTGCCGGGCATCGACGTGGCCGCCGTGCGCGCCCTGGCCGAGTCCCTCGGCGTCGAGTTCC
GGGAGCGCGAATTTGCCGAGGTGGGGTAA

Upstream 100 bases:

>100_bases
CCCTCGCGGGCTTGTCACGGCACGGCCGTTCGTGGTAGCCTTGTCGGCAGTGGCGGCTCTTCCGGCCGCCATCGGCATTC
ACGGACCGGGAAGGACCACC

Downstream 100 bases:

>100_bases
GCCCCGCCTCGGATGCATCCCCCTTTCGCATCCTCGCACGCAACCATTACCCCTCGCATTTCTGCAAACCTCATCGCGCC
GATGCGGGGCATCATTGCAA

Product: TatD family deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MNESGFLIDTHAHIDGHDFAADFDAMLSRAWEAGLSHIVTVGADLESSRAAVALAGRHERIWCAVGIHPHDAGRVTDRCY
DEIRTLAQGNPKVAAIGEIGLDFFRDRSPRDEQEQVFRRFIRLARELALPIVVHDRDAHERVMAILREEKARDVGGVLHC
FSGDLAMARECVDMGFLISIPGTVTYPSNEALREVVRGVKIEHLLVETDCPYLTPVPHRGKRNEPAYVRLTAEKVAELKG
LSLEDVGRITSLNARRLFGIGESDQAARIAYRIRNSLYLNITNRCSNRCSFCAKFDDYTVKGHHLRLDHEPDSAEVLAAV
GEPGPVDEIVFCGFGEPMLRLDLIVEVARELKKRGFRIRINTDGQANLVHGRNVLPELQGLVDCISVSLNAADADTYARL
CNTPFGTNGFNGICRFLEEARLYIPTVVATAVTVPGIDVAAVRALAESLGVEFREREFAEVG

Sequences:

>Translated_462_residues
MNESGFLIDTHAHIDGHDFAADFDAMLSRAWEAGLSHIVTVGADLESSRAAVALAGRHERIWCAVGIHPHDAGRVTDRCY
DEIRTLAQGNPKVAAIGEIGLDFFRDRSPRDEQEQVFRRFIRLARELALPIVVHDRDAHERVMAILREEKARDVGGVLHC
FSGDLAMARECVDMGFLISIPGTVTYPSNEALREVVRGVKIEHLLVETDCPYLTPVPHRGKRNEPAYVRLTAEKVAELKG
LSLEDVGRITSLNARRLFGIGESDQAARIAYRIRNSLYLNITNRCSNRCSFCAKFDDYTVKGHHLRLDHEPDSAEVLAAV
GEPGPVDEIVFCGFGEPMLRLDLIVEVARELKKRGFRIRINTDGQANLVHGRNVLPELQGLVDCISVSLNAADADTYARL
CNTPFGTNGFNGICRFLEEARLYIPTVVATAVTVPGIDVAAVRALAESLGVEFREREFAEVG
>Mature_462_residues
MNESGFLIDTHAHIDGHDFAADFDAMLSRAWEAGLSHIVTVGADLESSRAAVALAGRHERIWCAVGIHPHDAGRVTDRCY
DEIRTLAQGNPKVAAIGEIGLDFFRDRSPRDEQEQVFRRFIRLARELALPIVVHDRDAHERVMAILREEKARDVGGVLHC
FSGDLAMARECVDMGFLISIPGTVTYPSNEALREVVRGVKIEHLLVETDCPYLTPVPHRGKRNEPAYVRLTAEKVAELKG
LSLEDVGRITSLNARRLFGIGESDQAARIAYRIRNSLYLNITNRCSNRCSFCAKFDDYTVKGHHLRLDHEPDSAEVLAAV
GEPGPVDEIVFCGFGEPMLRLDLIVEVARELKKRGFRIRINTDGQANLVHGRNVLPELQGLVDCISVSLNAADADTYARL
CNTPFGTNGFNGICRFLEEARLYIPTVVATAVTVPGIDVAAVRALAESLGVEFREREFAEVG

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=268, Percent_Identity=32.8358208955224, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI110349730, Length=268, Percent_Identity=32.4626865671642, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=32.4817518248175, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI226061614, Length=253, Percent_Identity=30.4347826086957, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI14042943, Length=197, Percent_Identity=32.994923857868, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI225903439, Length=180, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI225903424, Length=210, Percent_Identity=31.4285714285714, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI226061595, Length=231, Percent_Identity=31.1688311688312, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1787342, Length=261, Percent_Identity=40.9961685823755, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI48994985, Length=261, Percent_Identity=36.0153256704981, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=30.859375, Blast_Score=135, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=30.9608540925267, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=29.0076335877863, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17543026, Length=187, Percent_Identity=32.0855614973262, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17565396, Length=185, Percent_Identity=31.8918918918919, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648690, Length=290, Percent_Identity=28.2758620689655, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI221330018, Length=279, Percent_Identity=29.7491039426523, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24586117, Length=279, Percent_Identity=29.7491039426523, Blast_Score=101, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 51118; Mature: 51118

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESGFLIDTHAHIDGHDFAADFDAMLSRAWEAGLSHIVTVGADLESSRAAVALAGRHER
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCEEEEEECCCCE
IWCAVGIHPHDAGRVTDRCYDEIRTLAQGNPKVAAIGEIGLDFFRDRSPRDEQEQVFRRF
EEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHH
IRLARELALPIVVHDRDAHERVMAILREEKARDVGGVLHCFSGDLAMARECVDMGFLISI
HHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEC
PGTVTYPSNEALREVVRGVKIEHLLVETDCPYLTPVPHRGKRNEPAYVRLTAEKVAELKG
CCEEECCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHCC
LSLEDVGRITSLNARRLFGIGESDQAARIAYRIRNSLYLNITNRCSNRCSFCAKFDDYTV
CCHHHHCCHHCCCCHHEECCCCCCHHHHHHHHHHCCEEEEEHHHCCCHHCEEEECCCEEE
KGHHLRLDHEPDSAEVLAAVGEPGPVDEIVFCGFGEPMLRLDLIVEVARELKKRGFRIRI
CCCEEEECCCCCHHHHEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEE
NTDGQANLVHGRNVLPELQGLVDCISVSLNAADADTYARLCNTPFGTNGFNGICRFLEEA
ECCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHH
RLYIPTVVATAVTVPGIDVAAVRALAESLGVEFREREFAEVG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure
MNESGFLIDTHAHIDGHDFAADFDAMLSRAWEAGLSHIVTVGADLESSRAAVALAGRHER
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCEEEEEECCCCE
IWCAVGIHPHDAGRVTDRCYDEIRTLAQGNPKVAAIGEIGLDFFRDRSPRDEQEQVFRRF
EEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHH
IRLARELALPIVVHDRDAHERVMAILREEKARDVGGVLHCFSGDLAMARECVDMGFLISI
HHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEC
PGTVTYPSNEALREVVRGVKIEHLLVETDCPYLTPVPHRGKRNEPAYVRLTAEKVAELKG
CCEEECCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHCC
LSLEDVGRITSLNARRLFGIGESDQAARIAYRIRNSLYLNITNRCSNRCSFCAKFDDYTV
CCHHHHCCHHCCCCHHEECCCCCCHHHHHHHHHHCCEEEEEHHHCCCHHCEEEECCCEEE
KGHHLRLDHEPDSAEVLAAVGEPGPVDEIVFCGFGEPMLRLDLIVEVARELKKRGFRIRI
CCCEEEECCCCCHHHHEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEE
NTDGQANLVHGRNVLPELQGLVDCISVSLNAADADTYARLCNTPFGTNGFNGICRFLEEA
ECCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHH
RLYIPTVVATAVTVPGIDVAAVRALAESLGVEFREREFAEVG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]