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The map label for this gene is kdpE [H]

Identifier: 39997579

GI number: 39997579

Start: 2727480

End: 2728184

Strand: Direct

Name: kdpE [H]

Synonym: GSU2484

Alternate gene names: 39997579

Gene position: 2727480-2728184 (Clockwise)

Preceding gene: 39997578

Following gene: 39997580

Centisome position: 71.51

GC content: 68.23

Gene sequence:

>705_bases
ATGGGCCATGAAGCGAACGCCATCAACCGGCCGCGGATCCTGATCGTGGACGACGAAGCGGCGATCCGCCGCTTTCTCCG
CACCGTCCTCGACGCGGAGGAGTTCTCGCTCCACCAGGCCGAAACGGGTCACGCCGCGCTGGCCGCAGCCGCGGCCATCC
GGCCCGATCTCATCCTCCTGGATCTGGGGCTGCCGGACCTGGACGGGGTGGAGGTCATCAGGCGGATCAGGGAGTGGTCG
CCGGTGCCGATCATCGTGCTGTCGGTCCGGGAGCGGGAGGACGACAAGGTGCATGCCCTGGATGCCGGGGCGGACGACTA
CCTGACCAAGCCCTTCGGCATCGGGGAACTGCTGGCGAGGATGCGGGTGGTACTGCGCCGCTCCATCCGGCAGGCGCCCG
AACCGATCTGCCGGATCGGCGGGCTTGAGGTGGATCTGCCGCGCCGCCGCGTGACCGTGGACGGAGTCGAGGTACAGCTC
ACCCCCACCGAGTACGAGCTGCTGCGCCTCCTGGCGGTCCACGCCGGCAAGGTCCTGACCCACAGCCAGATCCTCCGGCA
GATCTGGGGGGTTGCCCATGTGGAACAGCCCCATGTGCTGCGGGTGAACATCAGCAATCTCCGCCGCAAGATCGAGTCCG
ATCCCACGCGCCCCCGCTACCTCCTGACCGAGCCCGGGGTCGGCTATCGTTTGAAGGCCGAGTGA

Upstream 100 bases:

>100_bases
GCCCACGGCGGCTCCATCCGGGCCGAGAACCGGACCGGGGGCGGGCTCCGGGTGATCGTGACCCTGCCGCTGGCCGGCGG
GGCGAAAGAGGGTGTTTCCC

Downstream 100 bases:

>100_bases
CCAGGGGCTCAACCATCAGGGGACAATCTGATGCTTGACCTGCCGGGGGAACGGGGCATACTATGGGGGACATTCATGCA
GCCGAGATCCGTTCGCGAGA

Product: DNA-binding response regulator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MGHEANAINRPRILIVDDEAAIRRFLRTVLDAEEFSLHQAETGHAALAAAAAIRPDLILLDLGLPDLDGVEVIRRIREWS
PVPIIVLSVREREDDKVHALDAGADDYLTKPFGIGELLARMRVVLRRSIRQAPEPICRIGGLEVDLPRRRVTVDGVEVQL
TPTEYELLRLLAVHAGKVLTHSQILRQIWGVAHVEQPHVLRVNISNLRRKIESDPTRPRYLLTEPGVGYRLKAE

Sequences:

>Translated_234_residues
MGHEANAINRPRILIVDDEAAIRRFLRTVLDAEEFSLHQAETGHAALAAAAAIRPDLILLDLGLPDLDGVEVIRRIREWS
PVPIIVLSVREREDDKVHALDAGADDYLTKPFGIGELLARMRVVLRRSIRQAPEPICRIGGLEVDLPRRRVTVDGVEVQL
TPTEYELLRLLAVHAGKVLTHSQILRQIWGVAHVEQPHVLRVNISNLRRKIESDPTRPRYLLTEPGVGYRLKAE
>Mature_233_residues
GHEANAINRPRILIVDDEAAIRRFLRTVLDAEEFSLHQAETGHAALAAAAAIRPDLILLDLGLPDLDGVEVIRRIREWSP
VPIIVLSVREREDDKVHALDAGADDYLTKPFGIGELLARMRVVLRRSIRQAPEPICRIGGLEVDLPRRRVTVDGVEVQLT
PTEYELLRLLAVHAGKVLTHSQILRQIWGVAHVEQPHVLRVNISNLRRKIESDPTRPRYLLTEPGVGYRLKAE

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=55.4545454545455, Blast_Score=239, Evalue=1e-64,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=35.1111111111111, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=36.036036036036, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=35.9090909090909, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=34.7639484978541, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=35.7142857142857, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=32.0175438596491, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=30, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=33.0316742081448, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=32.4444444444444, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=32.6086956521739, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=39.8230088495575, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=27.9475982532751, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790299, Length=113, Percent_Identity=33.6283185840708, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26334; Mature: 26203

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHEANAINRPRILIVDDEAAIRRFLRTVLDAEEFSLHQAETGHAALAAAAAIRPDLILL
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHCCCCEEEE
DLGLPDLDGVEVIRRIREWSPVPIIVLSVREREDDKVHALDAGADDYLTKPFGIGELLAR
ECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEECCCCCHHCCCCCCHHHHHHH
MRVVLRRSIRQAPEPICRIGGLEVDLPRRRVTVDGVEVQLTPTEYELLRLLAVHAGKVLT
HHHHHHHHHHHCCCHHHHHCCEEEECCCCEEEECCEEEEECCCHHHHHHHHHHHHCHHHH
HSQILRQIWGVAHVEQPHVLRVNISNLRRKIESDPTRPRYLLTEPGVGYRLKAE
HHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEEECCCCCEEEECC
>Mature Secondary Structure 
GHEANAINRPRILIVDDEAAIRRFLRTVLDAEEFSLHQAETGHAALAAAAAIRPDLILL
CCCCCCCCCCEEEEECCHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHCCCCEEEE
DLGLPDLDGVEVIRRIREWSPVPIIVLSVREREDDKVHALDAGADDYLTKPFGIGELLAR
ECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEECCCCCHHCCCCCCHHHHHHH
MRVVLRRSIRQAPEPICRIGGLEVDLPRRRVTVDGVEVQLTPTEYELLRLLAVHAGKVLT
HHHHHHHHHHHCCCHHHHHCCEEEECCCCEEEECCEEEEECCCHHHHHHHHHHHHCHHHH
HSQILRQIWGVAHVEQPHVLRVNISNLRRKIESDPTRPRYLLTEPGVGYRLKAE
HHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]