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The map label for this gene is kup2

Identifier: 39997580

GI number: 39997580

Start: 2728476

End: 2730293

Strand: Direct

Name: kup2

Synonym: GSU2485

Alternate gene names: 39997580

Gene position: 2728476-2730293 (Clockwise)

Preceding gene: 39997579

Following gene: 39997583

Centisome position: 71.54

GC content: 62.54

Gene sequence:

>1818_bases
ATGAAGACTGAAGCCCAATCCTACTGGGGCGGCATCATCAAATCCATGGGCCTGGTGTTCGGCGACATCGGCACCAGCCC
CATCTACACCCTCACGGTCATCATGACCCTGACCAAGCCCGACGCGGAGCACGTGCTCGGCATCCTCTCCCTCATCGTCT
GGACCCTCATCATCCTCGTCACGGTCGAGTACGCCTGGCTGGCCATGAGCCTGGGCCGCAAGGGCGAAGGGGGAACCATC
GTCCTGAAGGAGATCCTGATCCGGCTGCTCAAATCGGGACGCCAGATGGCCTTTGCGGGCTTTCTCGCCTTCCTCGGCGT
CTCGCTGCTCCTGGGCGACGGCGTCATCACCCCGGCCATCAGTATCCTCTCCGCCGTGGAGGGAATGCGGCTGATCCCCG
GCCTGGAGGACCTGGCCCAGGGGGGGCTGATCCTGGTGGCCGCGGTCATCGCGGTGTTTCTCTTCATCTTCCAGTTCAAG
GGAACGGACAAGGTGGCCAGCGCCTTCGGCCCCATCATGGTCGTCTGGTTCTCGGCCCTGACGGTGTCGGGGCTGGTCTC
GATCATCGGCACCCCCACGGTGGTCCAGGCGATCAGCCCCCACCACGCCGTCCTCTTCCTCAAGCACAACGGCCTGGCCG
GCTTTTTCGTCCTCTCCGAGGTCATCCTCTGCGCCACCGGCGGCGAGGCCCTCTACGCCGACATGGGGCACCTGGGGAGA
AAGCCGATCATCCGGGCCTGGTACTTCGTCTTCTGTGCCCTGGTCATCAACTACCTGGGCCAGGGGGCCTTCATCCTGCG
CAACCCCGAGGCCAAGAACATCCTCTTCTCCATGGTGAAGAGCCAGGTGCCGATGCTCTACATCCCGTTCCTGCTCCTCA
CCATCTCGGCCACGATCATCGCCTCCCAGGCCCTGATCAGCGGGGTGTTCTCCATCGTCTACCAGGGGATCACCACCCGC
ATCCTGCCGCTGATGAAAGTGGATTACACCTCGACCCACCTGAAGTCCCAGATCTACATCGGCTCGGTCAACTGGTCGCT
CCTGGTGGCGGTCATCTTCATCATGATCCTGTTCCAGCGGTCGGAAAACCTGGCCGCGGCCTACGGCCTGGCGGTGACCG
GCACCATGTTCATCACCGGCATCATGATGACCATGATCTTCTCCCGCACCACCAAGAAGTGGAAGGTCCCCATCGCCCTG
GCCGTGACCGTGATCGACTTCGCCTATCTCACCGCCAACCTGCACAAGCTGCCCCACGGCGGCTACTGGTCCCTGGTGCT
CGCCTCCATCCCCCTGGCGATCATGGTGATCTGGACCCGGGGCCAGCGGGCCCTCTACCGCTCCCTCAAGCCCCTGGACC
TGGACACCTTCCTCCTCTCCTACGAGCAAATCTACGCCAAGGGGCACAACATCCCCGGCACCGGGCTCTTTTTCGTGCGG
GAGACCCCCGTGGTGCCCCCCTACGTGATCCACTGCATCATCAGGAGCAACATCATCTACGAGCGGAACGTGTTCGTCTC
CCTGACGCGGACCGACGAGCCCTTTGACGTGAGGACGAAGCTGACGCGGGGAATCGGCACCGGGCTCGATGCCTTCGAGG
TCAACGCCGGCTACATGGAGCGGCTGGACATCGAGAAACTGCTCAAGAAACACGGGGTCGAGGAAAAGGTCATCTTTTAC
GGCATCGAGGACATCGACACCAGCAACCCCGTCTGGCGGATCTTTGCCACCATCAAGCGCCAGAGTGCCAACTTCGTCCA
GTTCAACAAGCTGCCGGTCAGCAAGCTTCAGGGGGTGGTGACGCGGGTCGAAATGTAG

Upstream 100 bases:

>100_bases
GCATCTGGAAGGGCACGACAGCGGTTTCAGGGCCGCCGGCGCCTGCCGGCGGCTTTTCCGTTTCCCGCCCCTTCATGCAT
ATCTTCCGGGAGGCGCGTAC

Downstream 100 bases:

>100_bases
CAGGGACGTTTTTCAACAGCCTGTTAGGTGTTCAGGAAGGTTTCAAAGGCCTGCCGGAGCGGAGCCCCCTCCCCTTCGAC
CACGTTGTAGAAGGCGCGCA

Product: potassium transporter family protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MKTEAQSYWGGIIKSMGLVFGDIGTSPIYTLTVIMTLTKPDAEHVLGILSLIVWTLIILVTVEYAWLAMSLGRKGEGGTI
VLKEILIRLLKSGRQMAFAGFLAFLGVSLLLGDGVITPAISILSAVEGMRLIPGLEDLAQGGLILVAAVIAVFLFIFQFK
GTDKVASAFGPIMVVWFSALTVSGLVSIIGTPTVVQAISPHHAVLFLKHNGLAGFFVLSEVILCATGGEALYADMGHLGR
KPIIRAWYFVFCALVINYLGQGAFILRNPEAKNILFSMVKSQVPMLYIPFLLLTISATIIASQALISGVFSIVYQGITTR
ILPLMKVDYTSTHLKSQIYIGSVNWSLLVAVIFIMILFQRSENLAAAYGLAVTGTMFITGIMMTMIFSRTTKKWKVPIAL
AVTVIDFAYLTANLHKLPHGGYWSLVLASIPLAIMVIWTRGQRALYRSLKPLDLDTFLLSYEQIYAKGHNIPGTGLFFVR
ETPVVPPYVIHCIIRSNIIYERNVFVSLTRTDEPFDVRTKLTRGIGTGLDAFEVNAGYMERLDIEKLLKKHGVEEKVIFY
GIEDIDTSNPVWRIFATIKRQSANFVQFNKLPVSKLQGVVTRVEM

Sequences:

>Translated_605_residues
MKTEAQSYWGGIIKSMGLVFGDIGTSPIYTLTVIMTLTKPDAEHVLGILSLIVWTLIILVTVEYAWLAMSLGRKGEGGTI
VLKEILIRLLKSGRQMAFAGFLAFLGVSLLLGDGVITPAISILSAVEGMRLIPGLEDLAQGGLILVAAVIAVFLFIFQFK
GTDKVASAFGPIMVVWFSALTVSGLVSIIGTPTVVQAISPHHAVLFLKHNGLAGFFVLSEVILCATGGEALYADMGHLGR
KPIIRAWYFVFCALVINYLGQGAFILRNPEAKNILFSMVKSQVPMLYIPFLLLTISATIIASQALISGVFSIVYQGITTR
ILPLMKVDYTSTHLKSQIYIGSVNWSLLVAVIFIMILFQRSENLAAAYGLAVTGTMFITGIMMTMIFSRTTKKWKVPIAL
AVTVIDFAYLTANLHKLPHGGYWSLVLASIPLAIMVIWTRGQRALYRSLKPLDLDTFLLSYEQIYAKGHNIPGTGLFFVR
ETPVVPPYVIHCIIRSNIIYERNVFVSLTRTDEPFDVRTKLTRGIGTGLDAFEVNAGYMERLDIEKLLKKHGVEEKVIFY
GIEDIDTSNPVWRIFATIKRQSANFVQFNKLPVSKLQGVVTRVEM
>Mature_605_residues
MKTEAQSYWGGIIKSMGLVFGDIGTSPIYTLTVIMTLTKPDAEHVLGILSLIVWTLIILVTVEYAWLAMSLGRKGEGGTI
VLKEILIRLLKSGRQMAFAGFLAFLGVSLLLGDGVITPAISILSAVEGMRLIPGLEDLAQGGLILVAAVIAVFLFIFQFK
GTDKVASAFGPIMVVWFSALTVSGLVSIIGTPTVVQAISPHHAVLFLKHNGLAGFFVLSEVILCATGGEALYADMGHLGR
KPIIRAWYFVFCALVINYLGQGAFILRNPEAKNILFSMVKSQVPMLYIPFLLLTISATIIASQALISGVFSIVYQGITTR
ILPLMKVDYTSTHLKSQIYIGSVNWSLLVAVIFIMILFQRSENLAAAYGLAVTGTMFITGIMMTMIFSRTTKKWKVPIAL
AVTVIDFAYLTANLHKLPHGGYWSLVLASIPLAIMVIWTRGQRALYRSLKPLDLDTFLLSYEQIYAKGHNIPGTGLFFVR
ETPVVPPYVIHCIIRSNIIYERNVFVSLTRTDEPFDVRTKLTRGIGTGLDAFEVNAGYMERLDIEKLLKKHGVEEKVIFY
GIEDIDTSNPVWRIFATIKRQSANFVQFNKLPVSKLQGVVTRVEM

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=620, Percent_Identity=33.7096774193548, Blast_Score=308, Evalue=6e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP2_GEOSL (Q74AA5)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_953531.1
- GeneID:   2688180
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU2485
- NMPDR:   fig|243231.1.peg.2469
- TIGR:   GSU2485
- HOGENOM:   HBG351154
- OMA:   IMMTMIF
- ProtClustDB:   CLSK900490
- BioCyc:   GSUL243231:GSU_2485-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 66674; Mature: 66674

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xff76cbc)-; HASH(0x10b968f0)-; HASH(0x10a7e280)-; HASH(0x10793480)-; HASH(0x109c2d88)-; HASH(0x10b4cdf4)-; HASH(0x10bb7088)-; HASH(0x10b8a384)-; HASH(0x10b8bdf0)-; HASH(0x10bba1d4)-; HASH(0xfac17ac)-; HASH(0x10b93894)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTEAQSYWGGIIKSMGLVFGDIGTSPIYTLTVIMTLTKPDAEHVLGILSLIVWTLIILV
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
TVEYAWLAMSLGRKGEGGTIVLKEILIRLLKSGRQMAFAGFLAFLGVSLLLGDGVITPAI
HHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
SILSAVEGMRLIPGLEDLAQGGLILVAAVIAVFLFIFQFKGTDKVASAFGPIMVVWFSAL
HHHHHHCCCHHCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TVSGLVSIIGTPTVVQAISPHHAVLFLKHNGLAGFFVLSEVILCATGGEALYADMGHLGR
HHHHHHHHHCCCHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHCCC
KPIIRAWYFVFCALVINYLGQGAFILRNPEAKNILFSMVKSQVPMLYIPFLLLTISATII
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ASQALISGVFSIVYQGITTRILPLMKVDYTSTHLKSQIYIGSVNWSLLVAVIFIMILFQR
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHCCEEEEECCCHHHHHHHHHHHHHHHC
SENLAAAYGLAVTGTMFITGIMMTMIFSRTTKKWKVPIALAVTVIDFAYLTANLHKLPHG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCC
GYWSLVLASIPLAIMVIWTRGQRALYRSLKPLDLDTFLLSYEQIYAKGHNIPGTGLFFVR
CHHHHHHHHHCHHEEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
ETPVVPPYVIHCIIRSNIIYERNVFVSLTRTDEPFDVRTKLTRGIGTGLDAFEVNAGYME
CCCCCCHHHHHHHHHCCEEEECCEEEEEECCCCCCHHHHHHHHHCCCCCCCEECCCCHHH
RLDIEKLLKKHGVEEKVIFYGIEDIDTSNPVWRIFATIKRQSANFVQFNKLPVSKLQGVV
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
TRVEM
HHCCH
>Mature Secondary Structure
MKTEAQSYWGGIIKSMGLVFGDIGTSPIYTLTVIMTLTKPDAEHVLGILSLIVWTLIILV
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
TVEYAWLAMSLGRKGEGGTIVLKEILIRLLKSGRQMAFAGFLAFLGVSLLLGDGVITPAI
HHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
SILSAVEGMRLIPGLEDLAQGGLILVAAVIAVFLFIFQFKGTDKVASAFGPIMVVWFSAL
HHHHHHCCCHHCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TVSGLVSIIGTPTVVQAISPHHAVLFLKHNGLAGFFVLSEVILCATGGEALYADMGHLGR
HHHHHHHHHCCCHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHCCC
KPIIRAWYFVFCALVINYLGQGAFILRNPEAKNILFSMVKSQVPMLYIPFLLLTISATII
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ASQALISGVFSIVYQGITTRILPLMKVDYTSTHLKSQIYIGSVNWSLLVAVIFIMILFQR
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHCCEEEEECCCHHHHHHHHHHHHHHHC
SENLAAAYGLAVTGTMFITGIMMTMIFSRTTKKWKVPIALAVTVIDFAYLTANLHKLPHG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCC
GYWSLVLASIPLAIMVIWTRGQRALYRSLKPLDLDTFLLSYEQIYAKGHNIPGTGLFFVR
CHHHHHHHHHCHHEEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
ETPVVPPYVIHCIIRSNIIYERNVFVSLTRTDEPFDVRTKLTRGIGTGLDAFEVNAGYME
CCCCCCHHHHHHHHHCCEEEECCEEEEEECCCCCCHHHHHHHHHCCCCCCCEECCCCHHH
RLDIEKLLKKHGVEEKVIFYGIEDIDTSNPVWRIFATIKRQSANFVQFNKLPVSKLQGVV
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
TRVEM
HHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA