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The map label for this gene is htpG [H]

Identifier: 39997485

GI number: 39997485

Start: 2620678

End: 2622630

Strand: Direct

Name: htpG [H]

Synonym: GSU2390

Alternate gene names: 39997485

Gene position: 2620678-2622630 (Clockwise)

Preceding gene: 39997465

Following gene: 39997490

Centisome position: 68.71

GC content: 62.52

Gene sequence:

>1953_bases
ATGAGCAAGACCGTCAAGAAATTCGAAACCGAAGTCCAGCAGCTCCTGGACCTCGTGATCCACTCCCTCTACTCCAACAA
GGACATCTTCCTGCGGGAGCTCATCTCCAACGCCTCCGACGCCATCGACAAAGTCCTCTTCGAGTCCCACCAGAACGCGG
CGGTCATCGAGGGCGAGCCCGAAGGGAAGATCAAGCTGATCCCCGACAAGGATGCCGGCACCCTTACCATCCGCGACAAC
GGGGTCGGCATGACCCTGGAGGAAGTGGAGAAGAACATCGGCACCATCGCCCATTCGGGCACCAAGGCATTCCTGGCCAA
CCTGAAGGAGCAGAACGTGGCCGACCACCCGGAGCTGATCGGCCAGTTCGGGGTCGGCTTCTACGCCTCGTTCATGGTGG
CCGACCGGGTCACCCTCGTCACCCGCCGGGCCGGCCACGACAAGGCGGCCGGGGTCCGCTGGGAGTCCACCGGCGACGGC
ACCTACACCGTGGAGGAATGCGCCAAAGAGACCCGCGGCACCGAGATCACCCTCCACCTGAAAGAAGAGATGAAGGAATA
CCTGGACGAGTGGAAGATCCGCTCCATCGTCCGCAAGTACTCCGACTACGTCCAGTACCCCATCGTCATGGACGTGACCC
GCACCGAAGTGCCCAAGGGGGTGAACGGCGAAGAGATCGAAGGGGCCGGCACCATCGAGAAGACCGAAGAGGAAACCCTC
AACTCCATGAAGGCCATCTGGACCCGCTCCAAAAGCGAGGTGACCGAGGAGGAGTACGAGGAGTTCTACAAGCACGTCTC
CCACGACTTTGAAAAGCCGCTGAAGACCATCCACTACTCGGCCGAGGGGACCAGCGAGTTCAAGGCCCTCCTCTACCTGC
CGGCCCACAAGCCCTTCGACCTCTTCATGCCCGAGCGCAAGAAAGGGGTCCAGCTCTACGTGCGCCGGGTCTTCATCACC
GACTCCTGCGAACAGCTCCTCCCCGACTACCTCCGCTTCGTCAAGGGAGTGGTGGACTCCAGCGACCTGCCCCTCAACGT
CTCCCGCGAGATCCTGCAGGAGGACGTGCAGATCAAGCGCATCCAGAAGAGCCTCGTCTCCAAGATCCTCTCAACCCTCT
CCGAGATGAGGGAAAAAGAGGCCGACAGCTACCTGGACTTCTACAAGGAGTTCGGCCCGGTCCTCAAGGAAGGGGTCCAC
TTCGACTACGCCAACCGGGACAAGCTCCAGGACCTTCTCCTGTTCGAGAGCACCGCCACCGACGCGGGTTCGTTCGTCTC
CCTCAAGGAATACGTGGAGCGGATGCCCGAGGGGCAGGAAGAGATCTACTTCATCACCGGCACCAGCCGGGCGGCCCTGG
AGCAGTCGCCGCACCTGGAGATCTTCCGCAAGAAGGGGTACGAAGTCCTGTTCCTGACCGATCCGGTGGACGAGTGGGTG
GTGCAGGGGCTGCCGGAATACGGCGGCAAAAAGCTCAAGGCCGTTGACCGGGGCGACGTGATCCCCGCCACCGAAGAAGA
GAAAAAAGAGCAGGAAGCCAAGCGGGAAGAGGCGGCCAAGCAGTACGGCGACCTCCTCTCCTTCGTAAAGGAGAAGCTGG
CCGAGCGGGTGAAAGAAGTGCGGCTCTCCAACCGCCTCACCGACAGCGCCTGCTGCCTGGTGGCCGACGAGCACGGCCTC
AACGCCAACATGGAGCGGATTCTCCGGGCCATGAACCAGACCGTGCCCGAGTCCAAGCGAATCCTGGAGCTGAACCCGGA
CCACCCCATCATGCAGGTCATGGCCACCCTCTTCGGCAAGGACAAGACCAACCCGCGCCTGGCCGACTACTGCGACCTCC
TCTACGACCAGGCCCTGCTCACCGAGGGATCGCCCATCGCCGACCCGCTCCGGTTCACCCGCCTCGTTGCCGAGCTGATG
GTGGCGGACGGCAAGGCCGCCGCGGGAGAATAG

Upstream 100 bases:

>100_bases
AAACACTACTCCGTCGCATCATCCCCCTTGAAATTCGCTCCGACCATGATTAGGTTAAAGACCACGCGCACACCACACCC
CAAAGGAGATCACCATCCCC

Downstream 100 bases:

>100_bases
GCCGGCAGGCCCCCCTTCCCCGCGCAGTACTCAGCACCAATCCATTCCAGATTCCCGCCATGGGGAGCCGAAGCATCGGC
TCCCCTTTTTTCGTTTCTAT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MSKTVKKFETEVQQLLDLVIHSLYSNKDIFLRELISNASDAIDKVLFESHQNAAVIEGEPEGKIKLIPDKDAGTLTIRDN
GVGMTLEEVEKNIGTIAHSGTKAFLANLKEQNVADHPELIGQFGVGFYASFMVADRVTLVTRRAGHDKAAGVRWESTGDG
TYTVEECAKETRGTEITLHLKEEMKEYLDEWKIRSIVRKYSDYVQYPIVMDVTRTEVPKGVNGEEIEGAGTIEKTEEETL
NSMKAIWTRSKSEVTEEEYEEFYKHVSHDFEKPLKTIHYSAEGTSEFKALLYLPAHKPFDLFMPERKKGVQLYVRRVFIT
DSCEQLLPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVSKILSTLSEMREKEADSYLDFYKEFGPVLKEGVH
FDYANRDKLQDLLLFESTATDAGSFVSLKEYVERMPEGQEEIYFITGTSRAALEQSPHLEIFRKKGYEVLFLTDPVDEWV
VQGLPEYGGKKLKAVDRGDVIPATEEEKKEQEAKREEAAKQYGDLLSFVKEKLAERVKEVRLSNRLTDSACCLVADEHGL
NANMERILRAMNQTVPESKRILELNPDHPIMQVMATLFGKDKTNPRLADYCDLLYDQALLTEGSPIADPLRFTRLVAELM
VADGKAAAGE

Sequences:

>Translated_650_residues
MSKTVKKFETEVQQLLDLVIHSLYSNKDIFLRELISNASDAIDKVLFESHQNAAVIEGEPEGKIKLIPDKDAGTLTIRDN
GVGMTLEEVEKNIGTIAHSGTKAFLANLKEQNVADHPELIGQFGVGFYASFMVADRVTLVTRRAGHDKAAGVRWESTGDG
TYTVEECAKETRGTEITLHLKEEMKEYLDEWKIRSIVRKYSDYVQYPIVMDVTRTEVPKGVNGEEIEGAGTIEKTEEETL
NSMKAIWTRSKSEVTEEEYEEFYKHVSHDFEKPLKTIHYSAEGTSEFKALLYLPAHKPFDLFMPERKKGVQLYVRRVFIT
DSCEQLLPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVSKILSTLSEMREKEADSYLDFYKEFGPVLKEGVH
FDYANRDKLQDLLLFESTATDAGSFVSLKEYVERMPEGQEEIYFITGTSRAALEQSPHLEIFRKKGYEVLFLTDPVDEWV
VQGLPEYGGKKLKAVDRGDVIPATEEEKKEQEAKREEAAKQYGDLLSFVKEKLAERVKEVRLSNRLTDSACCLVADEHGL
NANMERILRAMNQTVPESKRILELNPDHPIMQVMATLFGKDKTNPRLADYCDLLYDQALLTEGSPIADPLRFTRLVAELM
VADGKAAAGE
>Mature_649_residues
SKTVKKFETEVQQLLDLVIHSLYSNKDIFLRELISNASDAIDKVLFESHQNAAVIEGEPEGKIKLIPDKDAGTLTIRDNG
VGMTLEEVEKNIGTIAHSGTKAFLANLKEQNVADHPELIGQFGVGFYASFMVADRVTLVTRRAGHDKAAGVRWESTGDGT
YTVEECAKETRGTEITLHLKEEMKEYLDEWKIRSIVRKYSDYVQYPIVMDVTRTEVPKGVNGEEIEGAGTIEKTEEETLN
SMKAIWTRSKSEVTEEEYEEFYKHVSHDFEKPLKTIHYSAEGTSEFKALLYLPAHKPFDLFMPERKKGVQLYVRRVFITD
SCEQLLPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVSKILSTLSEMREKEADSYLDFYKEFGPVLKEGVHF
DYANRDKLQDLLLFESTATDAGSFVSLKEYVERMPEGQEEIYFITGTSRAALEQSPHLEIFRKKGYEVLFLTDPVDEWVV
QGLPEYGGKKLKAVDRGDVIPATEEEKKEQEAKREEAAKQYGDLLSFVKEKLAERVKEVRLSNRLTDSACCLVADEHGLN
ANMERILRAMNQTVPESKRILELNPDHPIMQVMATLFGKDKTNPRLADYCDLLYDQALLTEGSPIADPLRFTRLVAELMV
ADGKAAAGE

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI154146191, Length=672, Percent_Identity=41.3690476190476, Blast_Score=476, Evalue=1e-134,
Organism=Homo sapiens, GI20149594, Length=669, Percent_Identity=40.8071748878924, Blast_Score=473, Evalue=1e-133,
Organism=Homo sapiens, GI153792590, Length=672, Percent_Identity=41.3690476190476, Blast_Score=473, Evalue=1e-133,
Organism=Homo sapiens, GI4507677, Length=666, Percent_Identity=39.7897897897898, Blast_Score=439, Evalue=1e-123,
Organism=Homo sapiens, GI155722983, Length=650, Percent_Identity=34.1538461538462, Blast_Score=373, Evalue=1e-103,
Organism=Escherichia coli, GI1786679, Length=639, Percent_Identity=47.4178403755869, Blast_Score=584, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI17559162, Length=656, Percent_Identity=41.6158536585366, Blast_Score=486, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI17542208, Length=657, Percent_Identity=38.5083713850837, Blast_Score=411, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI115535205, Length=652, Percent_Identity=35.1226993865031, Blast_Score=357, Evalue=1e-98,
Organism=Caenorhabditis elegans, GI115535167, Length=437, Percent_Identity=37.7574370709382, Blast_Score=283, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6325016, Length=689, Percent_Identity=39.1872278664732, Blast_Score=464, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6323840, Length=683, Percent_Identity=39.2386530014641, Blast_Score=462, Evalue=1e-131,
Organism=Drosophila melanogaster, GI17647529, Length=703, Percent_Identity=41.8207681365576, Blast_Score=510, Evalue=1e-144,
Organism=Drosophila melanogaster, GI21357739, Length=678, Percent_Identity=38.2005899705015, Blast_Score=427, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24586016, Length=624, Percent_Identity=36.2179487179487, Blast_Score=374, Evalue=1e-103,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 73732; Mature: 73600

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTVKKFETEVQQLLDLVIHSLYSNKDIFLRELISNASDAIDKVLFESHQNAAVIEGEP
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
EGKIKLIPDKDAGTLTIRDNGVGMTLEEVEKNIGTIAHSGTKAFLANLKEQNVADHPELI
CCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHH
GQFGVGFYASFMVADRVTLVTRRAGHDKAAGVRWESTGDGTYTVEECAKETRGTEITLHL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEHHHHHHHHCCCEEEEEH
KEEMKEYLDEWKIRSIVRKYSDYVQYPIVMDVTRTEVPKGVNGEEIEGAGTIEKTEEETL
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHH
NSMKAIWTRSKSEVTEEEYEEFYKHVSHDFEKPLKTIHYSAEGTSEFKALLYLPAHKPFD
HHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCCCCCC
LFMPERKKGVQLYVRRVFITDSCEQLLPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKR
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
IQKSLVSKILSTLSEMREKEADSYLDFYKEFGPVLKEGVHFDYANRDKLQDLLLFESTAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
DAGSFVSLKEYVERMPEGQEEIYFITGTSRAALEQSPHLEIFRKKGYEVLFLTDPVDEWV
CCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHCCCCCHHHHHHCCCEEEEEECCHHHHH
VQGLPEYGGKKLKAVDRGDVIPATEEEKKEQEAKREEAAKQYGDLLSFVKEKLAERVKEV
HCCCHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLSNRLTDSACCLVADEHGLNANMERILRAMNQTVPESKRILELNPDHPIMQVMATLFGK
HHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCC
DKTNPRLADYCDLLYDQALLTEGSPIADPLRFTRLVAELMVADGKAAAGE
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SKTVKKFETEVQQLLDLVIHSLYSNKDIFLRELISNASDAIDKVLFESHQNAAVIEGEP
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
EGKIKLIPDKDAGTLTIRDNGVGMTLEEVEKNIGTIAHSGTKAFLANLKEQNVADHPELI
CCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHH
GQFGVGFYASFMVADRVTLVTRRAGHDKAAGVRWESTGDGTYTVEECAKETRGTEITLHL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEHHHHHHHHCCCEEEEEH
KEEMKEYLDEWKIRSIVRKYSDYVQYPIVMDVTRTEVPKGVNGEEIEGAGTIEKTEEETL
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHH
NSMKAIWTRSKSEVTEEEYEEFYKHVSHDFEKPLKTIHYSAEGTSEFKALLYLPAHKPFD
HHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCCCCCC
LFMPERKKGVQLYVRRVFITDSCEQLLPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKR
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
IQKSLVSKILSTLSEMREKEADSYLDFYKEFGPVLKEGVHFDYANRDKLQDLLLFESTAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
DAGSFVSLKEYVERMPEGQEEIYFITGTSRAALEQSPHLEIFRKKGYEVLFLTDPVDEWV
CCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHCCCCCHHHHHHCCCEEEEEECCHHHHH
VQGLPEYGGKKLKAVDRGDVIPATEEEKKEQEAKREEAAKQYGDLLSFVKEKLAERVKEV
HCCCHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLSNRLTDSACCLVADEHGLNANMERILRAMNQTVPESKRILELNPDHPIMQVMATLFGK
HHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCC
DKTNPRLADYCDLLYDQALLTEGSPIADPLRFTRLVAELMVADGKAAAGE
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA