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The map label for this gene is cysH [H]

Identifier: 39996815

GI number: 39996815

Start: 1880436

End: 1881143

Strand: Direct

Name: cysH [H]

Synonym: GSU1716

Alternate gene names: 39996815

Gene position: 1880436-1881143 (Clockwise)

Preceding gene: 39996811

Following gene: 39996816

Centisome position: 49.3

GC content: 62.43

Gene sequence:

>708_bases
ATGGCCATAGAGAAGCATTCATCACTGCCCCAGATCCCTGAAAATGCCACTCCACTGGAGATACTCAGAATTGGTATCGA
AGCGGCGGGCGGTGCCGTGAGCCTTGCCTGCTCCTTTTCAGTCGAAGACGTAATCATCATCGACCTGATCACGTCCCATG
ATCTTCCGGTGGGAATCTTCGCCATAGACACCGGGCGGCTTCCCGAGGAGACCCATGAGGTCGCCGAGGCTATCGTCTCC
AGGTACGGAGTGGGCATTGACTGGTATTTCCCCCGCAACGACGAGGTGGAGCGGCTGCTGCGGGGGAAAGGGCCGTTTTC
GTTCCGTGAAAGCCTTGTCAATCGCCACCAGTGTTGTCATATCCGCAAAGTGGAGCCGCTGGGGCGTGCCCTGGCGGGGC
TGGCCGGCTGGGTGACGGGCGTGCGGCGGGCCCACGGTGTGACACGGGCTAATCTCGCTCCTCTTGAGATTGATGACACC
AACGGCGGTATCGTGAAGATCAATCCCCTCCTGGACTGGACCGACTCCCAGGTATGGGCGTATGCGGAGGCACGGCGGCT
ACCGGTGAATCGCCTCCATCACCAGGGGTATCCGTCCATCGGCTGCGCCCCCTGCACCCGGGCCGTTACCCCAGGCCAGC
CCCCCCGGTCGGGGCGCTGGTGGTGGGAAGATCCTGAGCACAAGGAATGCGGGCTGCACCGGCGCTGA

Upstream 100 bases:

>100_bases
TCATTATCACTTATATCAAGTTTGATTGTTGGCAATATTGAATTTGTACACTTAATTATACGTATTTAGCCACGCTCGAG
ATCAAGAAGGGGAATAGCCC

Downstream 100 bases:

>100_bases
CGCTAACAAGACATCCAATCGGAGAGAATGAACCATGAACAGCCATCTTGACGAACTCGAAGCGCAATCCATCTACATCT
TTCGCGAGGCATACCGGAAG

Product: phosphatidylglycerophosphatase A

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MAIEKHSSLPQIPENATPLEILRIGIEAAGGAVSLACSFSVEDVIIIDLITSHDLPVGIFAIDTGRLPEETHEVAEAIVS
RYGVGIDWYFPRNDEVERLLRGKGPFSFRESLVNRHQCCHIRKVEPLGRALAGLAGWVTGVRRAHGVTRANLAPLEIDDT
NGGIVKINPLLDWTDSQVWAYAEARRLPVNRLHHQGYPSIGCAPCTRAVTPGQPPRSGRWWWEDPEHKECGLHRR

Sequences:

>Translated_235_residues
MAIEKHSSLPQIPENATPLEILRIGIEAAGGAVSLACSFSVEDVIIIDLITSHDLPVGIFAIDTGRLPEETHEVAEAIVS
RYGVGIDWYFPRNDEVERLLRGKGPFSFRESLVNRHQCCHIRKVEPLGRALAGLAGWVTGVRRAHGVTRANLAPLEIDDT
NGGIVKINPLLDWTDSQVWAYAEARRLPVNRLHHQGYPSIGCAPCTRAVTPGQPPRSGRWWWEDPEHKECGLHRR
>Mature_234_residues
AIEKHSSLPQIPENATPLEILRIGIEAAGGAVSLACSFSVEDVIIIDLITSHDLPVGIFAIDTGRLPEETHEVAEAIVSR
YGVGIDWYFPRNDEVERLLRGKGPFSFRESLVNRHQCCHIRKVEPLGRALAGLAGWVTGVRRAHGVTRANLAPLEIDDTN
GGIVKINPLLDWTDSQVWAYAEARRLPVNRLHHQGYPSIGCAPCTRAVTPGQPPRSGRWWWEDPEHKECGLHRR

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=205, Percent_Identity=26.8292682926829, Blast_Score=79, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6325425, Length=235, Percent_Identity=31.4893617021277, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 26094; Mature: 25963

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIEKHSSLPQIPENATPLEILRIGIEAAGGAVSLACSFSVEDVIIIDLITSHDLPVGIF
CCCCCCCCCCCCCCCCCHHHHHEEHHHCCCCEEEEEEECCCCCEEEEEEEECCCCCEEEE
AIDTGRLPEETHEVAEAIVSRYGVGIDWYFPRNDEVERLLRGKGPFSFRESLVNRHQCCH
EEECCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHC
IRKVEPLGRALAGLAGWVTGVRRAHGVTRANLAPLEIDDTNGGIVKINPLLDWTDSQVWA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCEEE
YAEARRLPVNRLHHQGYPSIGCAPCTRAVTPGQPPRSGRWWWEDPEHKECGLHRR
HHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AIEKHSSLPQIPENATPLEILRIGIEAAGGAVSLACSFSVEDVIIIDLITSHDLPVGIF
CCCCCCCCCCCCCCCCHHHHHEEHHHCCCCEEEEEEECCCCCEEEEEEEECCCCCEEEE
AIDTGRLPEETHEVAEAIVSRYGVGIDWYFPRNDEVERLLRGKGPFSFRESLVNRHQCCH
EEECCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHC
IRKVEPLGRALAGLAGWVTGVRRAHGVTRANLAPLEIDDTNGGIVKINPLLDWTDSQVWA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCEEE
YAEARRLPVNRLHHQGYPSIGCAPCTRAVTPGQPPRSGRWWWEDPEHKECGLHRR
HHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]