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The map label for this gene is cph1 [H]

Identifier: 39995583

GI number: 39995583

Start: 506171

End: 508039

Strand: Reverse

Name: cph1 [H]

Synonym: GSU0475

Alternate gene names: 39995583

Gene position: 508039-506171 (Counterclockwise)

Preceding gene: 39995594

Following gene: 39995579

Centisome position: 13.32

GC content: 60.03

Gene sequence:

>1869_bases
ATGACCAGCTCCGACCTCGTATCGCGAAGCGCACGCTTCGCCCTGGTGATGCTGTTCCTCGCCGCGCTCGTCCTGACGAG
CCGCGTCAACTATCTCTTATTTCATACGCTTACCGAAATCGTCACCGTAGTCGCGGGATGCGGCATCTTCATGGTCGCTT
GGCACGCCCGGCGCCAGATCGATAACCACTGCATTCTGCTCATCGGCATCTCCCACCTGTTCGTGGCAATCATTACCCTG
TTCCACGCCCTGAGCTACCGGGGGATGGGGGTCTTCCCCGGCGCGGGCACAAACCTCTCCACCCAGCTCTGGATCGGCTC
GCGACTGCTGCAGGGAGCGTCGCTGGCGCTTGCACCGCTGTTCGTCAGAAAGCGGCTCAATCCCTCTGTTACCGTTACCG
CTTACATGGCCGCAACGTCACTTTTCCTGCTGTCAATCCTGTGCGGGGATATCTTCCCCCTCTGCTTCTCGGACGAGGTG
GGGCTCACCCCGTTCAAAAAGGGCGCCGAGTTCCTGGCTGGGATATTCATTCTCGCTGCCCTGACAGGCTTGCTGACCAA
GCGCCGGCACTTCGACGCCCGAGTGTTCCGGATGCTTTCGCTCTCCCTGGTCTTTCTTGCAACGAGCGGCTTCGTTTTTG
CTCTCAACACCGGCATCTCCAGCCTCACCGGCATGACGGGACATCTGCTTACGCTCGGCGGCTTCATACTCATCTACCGC
GCCATGGTGGAAACGGGGCTGGAACGCCCCTACGATCTGCTGTTCCGTGACCTGAAAGAAAGCGAAGAGCGCTACCGCAG
CCTCTACAACAGGACTCCCGTCATGCTCCACTCCATTGACCGGGAGGGAAAAATCGTCAATGTCAGCGATTTTTGGCTGG
AAACCCTCGGCTACCGGCGCGACGAGGTGCTGGGCAGGCTTTCCGCCGATTTCATGACTGACGAGTCACGGTCGTACGTG
ATCGGGACGGTCGTCCCGGAATTCCTCCGTACCGGACGCACCAGAGATATCCCGCTCCATCTGCTGACCAGCAGCGGAAA
GGTCATCGACGTTCTCCTTTCGTCTGAGGCGGAACGAGATGAAGAGGGAGAAATCGTGCGTTCCCTGTCGGTCATGACCG
ACGTGACGGAGCAGCGGCGTGCGGCCCGGCAGATCGAGCGACTCAACGAAAGTCTCGCCTCCCGGGCCATGGACCTGGAA
GTGGCCAATGGCGACCTGGAGGCGTTCAACTACAGCGTCTCGCACGATCTGAGATCGCACCTGACCGTGATCCGGGGCTT
CAGCGACGTTCTGCTCGAGATCTGCACAGACAAACTCGACGATGAATGCCGCAGCTACGTGCGTCACATCGGGGAAGAGA
CGGGGCGCATGAACGGACTCATCGGCACCCTGCTCGACTTTTCCCGCGTGGCCCGCGTAGAACTGGAACGGGTACCGGTC
AACCTGAGCACGCTGGCAGAGGAAATTGCCCTGGAGCTCAGGATGAAGGACCAGGAGCGCATGGCAGAGTTCATCATTAT
CGATGACGCCGACGTGACCGCCGATCCGGGGCTCATGAGGGTTGTGATGGAGAATCTGCTGGGCAATGCCTGGAAATACA
CGGGCAGGCGGGAACAGGCCGTAATCGAGTTCGGCAAGGAAGAGATGGAGGGTCAAACCGTGTTTTTCGTCCGGGACAAC
GGAGCGGGGTTCTCGTCACAACAGGCCGACAAACTCTTTCTTCCCTTCCAGCGCCTCCACGGCCGGAGCGAATTCCCGGG
GCACGGCATCGGCCTCGCAACGGTCCACAGGATCATCTCCCGCCATGGTGGCACAATCTGGGCCCAAGGGGAAGAGGGCG
CCGGAGCCGTATTCTATTTTACGCTGTAA

Upstream 100 bases:

>100_bases
AGGGGGTATTTCTCCCTTGCGAAGCCAACTTGAAATGATATGGTATCTGTGATCCGAGCTTAATTAGCAGGATCAAAATA
ATAACTGATCATCCCTACTC

Downstream 100 bases:

>100_bases
CGCGGCAGTCATCAGCGGATGACGCCAGGGCGCGAATGCGCTCCTCGCTCCTCTGGCCCGGCAACCCATCCCGGAGCGCC
CGAAGATCCAGAAACCTCTC

Product: sensory box histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 622; Mature: 621

Protein sequence:

>622_residues
MTSSDLVSRSARFALVMLFLAALVLTSRVNYLLFHTLTEIVTVVAGCGIFMVAWHARRQIDNHCILLIGISHLFVAIITL
FHALSYRGMGVFPGAGTNLSTQLWIGSRLLQGASLALAPLFVRKRLNPSVTVTAYMAATSLFLLSILCGDIFPLCFSDEV
GLTPFKKGAEFLAGIFILAALTGLLTKRRHFDARVFRMLSLSLVFLATSGFVFALNTGISSLTGMTGHLLTLGGFILIYR
AMVETGLERPYDLLFRDLKESEERYRSLYNRTPVMLHSIDREGKIVNVSDFWLETLGYRRDEVLGRLSADFMTDESRSYV
IGTVVPEFLRTGRTRDIPLHLLTSSGKVIDVLLSSEAERDEEGEIVRSLSVMTDVTEQRRAARQIERLNESLASRAMDLE
VANGDLEAFNYSVSHDLRSHLTVIRGFSDVLLEICTDKLDDECRSYVRHIGEETGRMNGLIGTLLDFSRVARVELERVPV
NLSTLAEEIALELRMKDQERMAEFIIIDDADVTADPGLMRVVMENLLGNAWKYTGRREQAVIEFGKEEMEGQTVFFVRDN
GAGFSSQQADKLFLPFQRLHGRSEFPGHGIGLATVHRIISRHGGTIWAQGEEGAGAVFYFTL

Sequences:

>Translated_622_residues
MTSSDLVSRSARFALVMLFLAALVLTSRVNYLLFHTLTEIVTVVAGCGIFMVAWHARRQIDNHCILLIGISHLFVAIITL
FHALSYRGMGVFPGAGTNLSTQLWIGSRLLQGASLALAPLFVRKRLNPSVTVTAYMAATSLFLLSILCGDIFPLCFSDEV
GLTPFKKGAEFLAGIFILAALTGLLTKRRHFDARVFRMLSLSLVFLATSGFVFALNTGISSLTGMTGHLLTLGGFILIYR
AMVETGLERPYDLLFRDLKESEERYRSLYNRTPVMLHSIDREGKIVNVSDFWLETLGYRRDEVLGRLSADFMTDESRSYV
IGTVVPEFLRTGRTRDIPLHLLTSSGKVIDVLLSSEAERDEEGEIVRSLSVMTDVTEQRRAARQIERLNESLASRAMDLE
VANGDLEAFNYSVSHDLRSHLTVIRGFSDVLLEICTDKLDDECRSYVRHIGEETGRMNGLIGTLLDFSRVARVELERVPV
NLSTLAEEIALELRMKDQERMAEFIIIDDADVTADPGLMRVVMENLLGNAWKYTGRREQAVIEFGKEEMEGQTVFFVRDN
GAGFSSQQADKLFLPFQRLHGRSEFPGHGIGLATVHRIISRHGGTIWAQGEEGAGAVFYFTL
>Mature_621_residues
TSSDLVSRSARFALVMLFLAALVLTSRVNYLLFHTLTEIVTVVAGCGIFMVAWHARRQIDNHCILLIGISHLFVAIITLF
HALSYRGMGVFPGAGTNLSTQLWIGSRLLQGASLALAPLFVRKRLNPSVTVTAYMAATSLFLLSILCGDIFPLCFSDEVG
LTPFKKGAEFLAGIFILAALTGLLTKRRHFDARVFRMLSLSLVFLATSGFVFALNTGISSLTGMTGHLLTLGGFILIYRA
MVETGLERPYDLLFRDLKESEERYRSLYNRTPVMLHSIDREGKIVNVSDFWLETLGYRRDEVLGRLSADFMTDESRSYVI
GTVVPEFLRTGRTRDIPLHLLTSSGKVIDVLLSSEAERDEEGEIVRSLSVMTDVTEQRRAARQIERLNESLASRAMDLEV
ANGDLEAFNYSVSHDLRSHLTVIRGFSDVLLEICTDKLDDECRSYVRHIGEETGRMNGLIGTLLDFSRVARVELERVPVN
LSTLAEEIALELRMKDQERMAEFIIIDDADVTADPGLMRVVMENLLGNAWKYTGRREQAVIEFGKEEMEGQTVFFVRDNG
AGFSSQQADKLFLPFQRLHGRSEFPGHGIGLATVHRIISRHGGTIWAQGEEGAGAVFYFTL

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=349, Percent_Identity=26.3610315186246, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=30.0884955752212, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI48994928, Length=259, Percent_Identity=27.7992277992278, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786600, Length=437, Percent_Identity=24.2562929061785, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=25.5411255411255, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=220, Percent_Identity=31.8181818181818, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=28.75, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=196, Percent_Identity=27.5510204081633, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1790861, Length=226, Percent_Identity=25.2212389380531, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69419; Mature: 69288

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSDLVSRSARFALVMLFLAALVLTSRVNYLLFHTLTEIVTVVAGCGIFMVAWHARRQI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
DNHCILLIGISHLFVAIITLFHALSYRGMGVFPGAGTNLSTQLWIGSRLLQGASLALAPL
CCCEEEEEEHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHCCCHHHHHHH
FVRKRLNPSVTVTAYMAATSLFLLSILCGDIFPLCFSDEVGLTPFKKGAEFLAGIFILAA
HHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LTGLLTKRRHFDARVFRMLSLSLVFLATSGFVFALNTGISSLTGMTGHLLTLGGFILIYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHCCCHHHHHHHHHHHHHH
AMVETGLERPYDLLFRDLKESEERYRSLYNRTPVMLHSIDREGKIVNVSDFWLETLGYRR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHHHCCCH
DEVLGRLSADFMTDESRSYVIGTVVPEFLRTGRTRDIPLHLLTSSGKVIDVLLSSEAERD
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCC
EEGEIVRSLSVMTDVTEQRRAARQIERLNESLASRAMDLEVANGDLEAFNYSVSHDLRSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHCCHHHHHHHHH
LTVIRGFSDVLLEICTDKLDDECRSYVRHIGEETGRMNGLIGTLLDFSRVARVELERVPV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NLSTLAEEIALELRMKDQERMAEFIIIDDADVTADPGLMRVVMENLLGNAWKYTGRREQA
CHHHHHHHHHHHHHCCCHHCCEEEEEEECCCCCCCCHHHHHHHHHHHCCHHHCCCCHHHH
VIEFGKEEMEGQTVFFVRDNGAGFSSQQADKLFLPFQRLHGRSEFPGHGIGLATVHRIIS
HHHHCHHHCCCCEEEEEECCCCCCCCCCCCHHCCCHHHHCCCCCCCCCCCCHHHHHHHHH
RHGGTIWAQGEEGAGAVFYFTL
HCCCEEEEECCCCCCEEEEEEC
>Mature Secondary Structure 
TSSDLVSRSARFALVMLFLAALVLTSRVNYLLFHTLTEIVTVVAGCGIFMVAWHARRQI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
DNHCILLIGISHLFVAIITLFHALSYRGMGVFPGAGTNLSTQLWIGSRLLQGASLALAPL
CCCEEEEEEHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHCCCHHHHHHH
FVRKRLNPSVTVTAYMAATSLFLLSILCGDIFPLCFSDEVGLTPFKKGAEFLAGIFILAA
HHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LTGLLTKRRHFDARVFRMLSLSLVFLATSGFVFALNTGISSLTGMTGHLLTLGGFILIYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHCCCHHHHHHHHHHHHHH
AMVETGLERPYDLLFRDLKESEERYRSLYNRTPVMLHSIDREGKIVNVSDFWLETLGYRR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHHHCCCH
DEVLGRLSADFMTDESRSYVIGTVVPEFLRTGRTRDIPLHLLTSSGKVIDVLLSSEAERD
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCC
EEGEIVRSLSVMTDVTEQRRAARQIERLNESLASRAMDLEVANGDLEAFNYSVSHDLRSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHCCHHHHHHHHH
LTVIRGFSDVLLEICTDKLDDECRSYVRHIGEETGRMNGLIGTLLDFSRVARVELERVPV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NLSTLAEEIALELRMKDQERMAEFIIIDDADVTADPGLMRVVMENLLGNAWKYTGRREQA
CHHHHHHHHHHHHHCCCHHCCEEEEEEECCCCCCCCHHHHHHHHHHHCCHHHCCCCHHHH
VIEFGKEEMEGQTVFFVRDNGAGFSSQQADKLFLPFQRLHGRSEFPGHGIGLATVHRIIS
HHHHCHHHCCCCEEEEEECCCCCCCCCCCCHHCCCHHHHCCCCCCCCCCCCHHHHHHHHH
RHGGTIWAQGEEGAGAVFYFTL
HCCCEEEEECCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]