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The map label for this gene is prmA

Identifier: 39995555

GI number: 39995555

Start: 477851

End: 478750

Strand: Reverse

Name: prmA

Synonym: GSU0447

Alternate gene names: 39995555

Gene position: 478750-477851 (Counterclockwise)

Preceding gene: 39995557

Following gene: 39995554

Centisome position: 12.55

GC content: 67.0

Gene sequence:

>900_bases
ATGGATAAACAATGGGCCGAAGTTTGCTGCCAGGTCCCGGCCGGACTGGTCGACCTGCTGGCCGATTTTCTCGTGGAGCT
CTCCGGCAATGGCGTCAGCATCGACAACCGGGCGCTTGACACCTTCACCCTGGACGGCATCGAGGAACTGGACACCGCAA
CCGTGCGGGCCTACTTCGATCCGGCAACGGACATGGCAGGGCAGATCGCCCAGATCGAGCGGTTCCTTGGTGACAACGCA
GCCGCCTTCGGCGGCGCCCCCATCCCCGCCCCCACCGTCACCCTCATCCGCGACGAAGACTGGGCCACCGGCTGGCGCCA
GCACTTCGTCCCCACCCGCATCGGCCGTCATCTGGTCATCAAGCCTACGTGGGAACCGTTCGCCCCAGAACCGGGAGACC
AAGTCATCGAGCTGGACCCCGGCATGGCCTTCGGCACCGGCACGCACCCCACCACGCGACTCTGCCTGGAGGCCCTGGAA
ACGCTCGGGCGCCCCGACAGGGTACTCGACGTGGGAACCGGGTCGGGCATCCTGGCCATCGCGGCCGTCCGGCTGGGGGC
CCGGCAGGTGATCGGCACCGATATCGACCCGGACGCCGTGATCGTGGCCGGGGAGAACTGCGCGCTCAACGGCGTTGAGG
TTGAACTGGTCACCACCCCCCTGGCCCTGATTCCGGGACGCTTCGATGTGGTGCTGGCCAACATTCTGGCCGAAGACCTG
GTCCGCATGGCCGGGGACTTGGCCGCAAAGGTCGCGGCTGGCGGGCACCTGATCCTCTCGGGCATCCTCACGGAGCGGGA
AGCCTTCGTCGTCGAGGGATTCGGCCGGAGCGGTCTCGCGCTGGTGGCAGTCTCCCGGGAAGGGGAATGGAGTTGTCTCG
TATACCGGAACGAGGGGTGA

Upstream 100 bases:

>100_bases
GACGGTTTGTCAAGGTTTTTATTGTCATAATCTTTTAGTTTTGGTACGTTAGCACACCCTGCCACCCCCCCGGCAGACTC
AAACTTACCGAGGTACAGGC

Downstream 100 bases:

>100_bases
GCATGCGCCGGTTTATCGTCACGGGCCTTGATCTGTCGGGTAAAAACGTGGTTGTGCGGGGGGACCTTTTTCGTCACATG
GCCCGGTCGCTTCGTCTAAA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDKQWAEVCCQVPAGLVDLLADFLVELSGNGVSIDNRALDTFTLDGIEELDTATVRAYFDPATDMAGQIAQIERFLGDNA
AAFGGAPIPAPTVTLIRDEDWATGWRQHFVPTRIGRHLVIKPTWEPFAPEPGDQVIELDPGMAFGTGTHPTTRLCLEALE
TLGRPDRVLDVGTGSGILAIAAVRLGARQVIGTDIDPDAVIVAGENCALNGVEVELVTTPLALIPGRFDVVLANILAEDL
VRMAGDLAAKVAAGGHLILSGILTEREAFVVEGFGRSGLALVAVSREGEWSCLVYRNEG

Sequences:

>Translated_299_residues
MDKQWAEVCCQVPAGLVDLLADFLVELSGNGVSIDNRALDTFTLDGIEELDTATVRAYFDPATDMAGQIAQIERFLGDNA
AAFGGAPIPAPTVTLIRDEDWATGWRQHFVPTRIGRHLVIKPTWEPFAPEPGDQVIELDPGMAFGTGTHPTTRLCLEALE
TLGRPDRVLDVGTGSGILAIAAVRLGARQVIGTDIDPDAVIVAGENCALNGVEVELVTTPLALIPGRFDVVLANILAEDL
VRMAGDLAAKVAAGGHLILSGILTEREAFVVEGFGRSGLALVAVSREGEWSCLVYRNEG
>Mature_299_residues
MDKQWAEVCCQVPAGLVDLLADFLVELSGNGVSIDNRALDTFTLDGIEELDTATVRAYFDPATDMAGQIAQIERFLGDNA
AAFGGAPIPAPTVTLIRDEDWATGWRQHFVPTRIGRHLVIKPTWEPFAPEPGDQVIELDPGMAFGTGTHPTTRLCLEALE
TLGRPDRVLDVGTGSGILAIAAVRLGARQVIGTDIDPDAVIVAGENCALNGVEVELVTTPLALIPGRFDVVLANILAEDL
VRMAGDLAAKVAAGGHLILSGILTEREAFVVEGFGRSGLALVAVSREGEWSCLVYRNEG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=244, Percent_Identity=40.9836065573771, Blast_Score=111, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_GEOSL (Q74G05)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951506.1
- ProteinModelPortal:   Q74G05
- SMR:   Q74G05
- GeneID:   2686328
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0447
- NMPDR:   fig|243231.1.peg.444
- TIGR:   GSU0447
- HOGENOM:   HBG584653
- OMA:   AIDIDDW
- ProtClustDB:   CLSK827836
- BioCyc:   GSUL243231:GSU_0447-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31736; Mature: 31736

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKQWAEVCCQVPAGLVDLLADFLVELSGNGVSIDNRALDTFTLDGIEELDTATVRAYFD
CCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCHHHHCCEEEEEEEC
PATDMAGQIAQIERFLGDNAAAFGGAPIPAPTVTLIRDEDWATGWRQHFVPTRIGRHLVI
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHCCHHHHCCEEEE
KPTWEPFAPEPGDQVIELDPGMAFGTGTHPTTRLCLEALETLGRPDRVLDVGTGSGILAI
ECCCCCCCCCCCCCEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHH
AAVRLGARQVIGTDIDPDAVIVAGENCALNGVEVELVTTPLALIPGRFDVVLANILAEDL
HHHHHCCHHHCCCCCCCCEEEEECCCEEECCEEEEEEECCHHHCCCHHHHHHHHHHHHHH
VRMAGDLAAKVAAGGHLILSGILTEREAFVVEGFGRSGLALVAVSREGEWSCLVYRNEG
HHHHHHHHHHHHCCCEEEEEHHHCCCCEEEEECCCCCCEEEEEEECCCCEEEEEEECCC
>Mature Secondary Structure
MDKQWAEVCCQVPAGLVDLLADFLVELSGNGVSIDNRALDTFTLDGIEELDTATVRAYFD
CCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCHHHHCCEEEEEEEC
PATDMAGQIAQIERFLGDNAAAFGGAPIPAPTVTLIRDEDWATGWRQHFVPTRIGRHLVI
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHCCHHHHCCEEEE
KPTWEPFAPEPGDQVIELDPGMAFGTGTHPTTRLCLEALETLGRPDRVLDVGTGSGILAI
ECCCCCCCCCCCCCEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHH
AAVRLGARQVIGTDIDPDAVIVAGENCALNGVEVELVTTPLALIPGRFDVVLANILAEDL
HHHHHCCHHHCCCCCCCCEEEEECCCEEECCEEEEEEECCHHHCCCHHHHHHHHHHHHHH
VRMAGDLAAKVAAGGHLILSGILTEREAFVVEGFGRSGLALVAVSREGEWSCLVYRNEG
HHHHHHHHHHHHCCCEEEEEHHHCCCCEEEEECCCCCCEEEEEEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA