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The map label for this gene is ftsW [C]

Identifier: 38234174

GI number: 38234174

Start: 1628720

End: 1630228

Strand: Reverse

Name: ftsW [C]

Synonym: DIP1599

Alternate gene names: 38234174

Gene position: 1630228-1628720 (Counterclockwise)

Preceding gene: 38234175

Following gene: 38234173

Centisome position: 65.51

GC content: 50.1

Gene sequence:

>1509_bases
ATGAGCACCAACACTTCGAATCGTGGCTCTCGGGTTCGTGACCGGATAGCGAGTTTTTTGGGCGAAATGATGCGCCGACC
GCTGACGGATTATTACATCGTCATGTTCGTTATCGCCTTGTTGGTGCTCACTGGCGTTTTGATGGTGGTTACCTCGTCGA
TGGCAACCTCTGTTTCAGAAACCGGTAGTGCATGGACTTACGCGACCAAGCAGATTTTGCTGATTGTTATCGGTTTTATC
GCCATGATCGGTGTCATGCAGATGCCACCGCGTAAGGTGAGAAAATACGCCGTGTGGCTGATGCGTATTTCGATTCTCCT
TCTCATCGTGGTGCTCATTCCTGGCATTGGTACCGGTAAAGAACAAGTCGGTTCGCAGTCGTGGATTCCGCTTGGGCCTG
TAAACATTCAGCCTTCAGAGATCGCGCGTGTGGCCTTAGCGATTTGGGGAGCAAGTTTTCTTACCCGTAAACCTAAAGTG
TATTTCCGCTTTTATGGGATTGATTTCGATCGCCGTGCGATGTTTGCCGTTATTGCTGGATTCACCTGTGCATTAGTCAT
GGCTGAGGGGGATCTTGGTATGACGGCGATGCTCGGATTTCTCACGTTGATTATGCTCGTATTCGCAGGGCTACCGCGAG
GTTTAATTGTTGCAGCATTGACAATTTCTGGCGTGGCTTTCGTTTTGGCAGTCACGATGCATGGGTATCGCGGTCACCGC
ATCACTGTTTTTATAGATGCGCTCTTTGGCCGATTTGATGATATCGATGGCGTAGCATATCAGTCTTATCAGGGCATATT
ATCGCTTGCCGATGGATCCTTTACGGGATTGGGGATCGGTCAGTCACGAGCTAAATGGTTTTATCTTCCAGAGGCGAAAA
ACGACTTCATTTTTGCCATTGTTGGAGAAGAGCTTGGTTTTGTCGGAGCCGCCATCATCATTGGGTTATTTACCGCGCTC
CTTCTTATTGCGTTAAGAATTGCACTGAGAATTAAAGACAGTTTCCTTTCTCTTGCTGTTGCTACTCTTGCCGCAGGTAT
TTCTTTGCAGGCTTTTATCAACATGGCCTATGTGATTGGTCTTCTTCCGGTTACTGGTATTCAACTACCTTTGATTTCTG
CCGGTGGCAGTTCTGCGGTGATTACGCTGGCGGCACTGGGGTTGATCGCAAACTGTGCACGCTATGAGCCAGAAGCGATT
TCAGCGATGCAGTCCTATGGAAGACCAGCCTTGGACCGAGTGCTGTTCTTGCGGGAGCCGGATGTATCCGATATTCGTAC
GCGTCGTTCTACACGGCGGTCTTCACAGGGAACACGCCAATCTGGTGCTCCCAAGAGGCAACCGCCGAAGATCGAACGCA
ATGAGCGAGTGAGCTACCGTCAAAGTTCAACAGGCACGTGGGGTTCGAGTGACCGCGATAGAACTGGTAGCGTCGACAAG
CAGCGGGGAGCACAGCGCCAACCTCGACGTCGAAATTATCCACAAGACAACAAACGCAGGAGAAGATGA

Upstream 100 bases:

>100_bases
TTGATATGTACACCGGCATGGGGCAGCGTGGAGACATGTTCGCTACAGCGATTGCACAACATTTACACGACTAACATTTT
TGTCGGTGAGGAGCACCACA

Downstream 100 bases:

>100_bases
AGTGAACACTCCACGAGTCGTAGTCGCAGGTGGCGGCACAGCTGGGCATATTGAGCCAGCTCTTGCCGTGGCAGAGTCGC
TACGTCACCGAGGTGCAGAG

Product: putative cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSTNTSNRGSRVRDRIASFLGEMMRRPLTDYYIVMFVIALLVLTGVLMVVTSSMATSVSETGSAWTYATKQILLIVIGFI
AMIGVMQMPPRKVRKYAVWLMRISILLLIVVLIPGIGTGKEQVGSQSWIPLGPVNIQPSEIARVALAIWGASFLTRKPKV
YFRFYGIDFDRRAMFAVIAGFTCALVMAEGDLGMTAMLGFLTLIMLVFAGLPRGLIVAALTISGVAFVLAVTMHGYRGHR
ITVFIDALFGRFDDIDGVAYQSYQGILSLADGSFTGLGIGQSRAKWFYLPEAKNDFIFAIVGEELGFVGAAIIIGLFTAL
LLIALRIALRIKDSFLSLAVATLAAGISLQAFINMAYVIGLLPVTGIQLPLISAGGSSAVITLAALGLIANCARYEPEAI
SAMQSYGRPALDRVLFLREPDVSDIRTRRSTRRSSQGTRQSGAPKRQPPKIERNERVSYRQSSTGTWGSSDRDRTGSVDK
QRGAQRQPRRRNYPQDNKRRRR

Sequences:

>Translated_502_residues
MSTNTSNRGSRVRDRIASFLGEMMRRPLTDYYIVMFVIALLVLTGVLMVVTSSMATSVSETGSAWTYATKQILLIVIGFI
AMIGVMQMPPRKVRKYAVWLMRISILLLIVVLIPGIGTGKEQVGSQSWIPLGPVNIQPSEIARVALAIWGASFLTRKPKV
YFRFYGIDFDRRAMFAVIAGFTCALVMAEGDLGMTAMLGFLTLIMLVFAGLPRGLIVAALTISGVAFVLAVTMHGYRGHR
ITVFIDALFGRFDDIDGVAYQSYQGILSLADGSFTGLGIGQSRAKWFYLPEAKNDFIFAIVGEELGFVGAAIIIGLFTAL
LLIALRIALRIKDSFLSLAVATLAAGISLQAFINMAYVIGLLPVTGIQLPLISAGGSSAVITLAALGLIANCARYEPEAI
SAMQSYGRPALDRVLFLREPDVSDIRTRRSTRRSSQGTRQSGAPKRQPPKIERNERVSYRQSSTGTWGSSDRDRTGSVDK
QRGAQRQPRRRNYPQDNKRRRR
>Mature_501_residues
STNTSNRGSRVRDRIASFLGEMMRRPLTDYYIVMFVIALLVLTGVLMVVTSSMATSVSETGSAWTYATKQILLIVIGFIA
MIGVMQMPPRKVRKYAVWLMRISILLLIVVLIPGIGTGKEQVGSQSWIPLGPVNIQPSEIARVALAIWGASFLTRKPKVY
FRFYGIDFDRRAMFAVIAGFTCALVMAEGDLGMTAMLGFLTLIMLVFAGLPRGLIVAALTISGVAFVLAVTMHGYRGHRI
TVFIDALFGRFDDIDGVAYQSYQGILSLADGSFTGLGIGQSRAKWFYLPEAKNDFIFAIVGEELGFVGAAIIIGLFTALL
LIALRIALRIKDSFLSLAVATLAAGISLQAFINMAYVIGLLPVTGIQLPLISAGGSSAVITLAALGLIANCARYEPEAIS
AMQSYGRPALDRVLFLREPDVSDIRTRRSTRRSSQGTRQSGAPKRQPPKIERNERVSYRQSSTGTWGSSDRDRTGSVDKQ
RGAQRQPRRRNYPQDNKRRRR

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=364, Percent_Identity=32.4175824175824, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1786853, Length=342, Percent_Identity=29.5321637426901, Blast_Score=115, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 55041; Mature: 54909

Theoretical pI: Translated: 11.10; Mature: 11.10

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNTSNRGSRVRDRIASFLGEMMRRPLTDYYIVMFVIALLVLTGVLMVVTSSMATSVSE
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGSAWTYATKQILLIVIGFIAMIGVMQMPPRKVRKYAVWLMRISILLLIVVLIPGIGTGK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
EQVGSQSWIPLGPVNIQPSEIARVALAIWGASFLTRKPKVYFRFYGIDFDRRAMFAVIAG
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHH
FTCALVMAEGDLGMTAMLGFLTLIMLVFAGLPRGLIVAALTISGVAFVLAVTMHGYRGHR
HHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCE
ITVFIDALFGRFDDIDGVAYQSYQGILSLADGSFTGLGIGQSRAKWFYLPEAKNDFIFAI
EEEEHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCCCCCEEEEE
VGEELGFVGAAIIIGLFTALLLIALRIALRIKDSFLSLAVATLAAGISLQAFINMAYVIG
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LLPVTGIQLPLISAGGSSAVITLAALGLIANCARYEPEAISAMQSYGRPALDRVLFLREP
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHEECCC
DVSDIRTRRSTRRSSQGTRQSGAPKRQPPKIERNERVSYRQSSTGTWGSSDRDRTGSVDK
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QRGAQRQPRRRNYPQDNKRRRR
HCCCCCCCHHCCCCCCHHHCCC
>Mature Secondary Structure 
STNTSNRGSRVRDRIASFLGEMMRRPLTDYYIVMFVIALLVLTGVLMVVTSSMATSVSE
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGSAWTYATKQILLIVIGFIAMIGVMQMPPRKVRKYAVWLMRISILLLIVVLIPGIGTGK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
EQVGSQSWIPLGPVNIQPSEIARVALAIWGASFLTRKPKVYFRFYGIDFDRRAMFAVIAG
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHH
FTCALVMAEGDLGMTAMLGFLTLIMLVFAGLPRGLIVAALTISGVAFVLAVTMHGYRGHR
HHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCE
ITVFIDALFGRFDDIDGVAYQSYQGILSLADGSFTGLGIGQSRAKWFYLPEAKNDFIFAI
EEEEHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCCCCCEEEEE
VGEELGFVGAAIIIGLFTALLLIALRIALRIKDSFLSLAVATLAAGISLQAFINMAYVIG
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LLPVTGIQLPLISAGGSSAVITLAALGLIANCARYEPEAISAMQSYGRPALDRVLFLREP
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHEECCC
DVSDIRTRRSTRRSSQGTRQSGAPKRQPPKIERNERVSYRQSSTGTWGSSDRDRTGSVDK
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QRGAQRQPRRRNYPQDNKRRRR
HCCCCCCCHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]