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The map label for this gene is murG

Identifier: 38234173

GI number: 38234173

Start: 1627639

End: 1628718

Strand: Reverse

Name: murG

Synonym: DIP1598

Alternate gene names: 38234173

Gene position: 1628718-1627639 (Counterclockwise)

Preceding gene: 38234174

Following gene: 38234172

Centisome position: 65.45

GC content: 50.37

Gene sequence:

>1080_bases
GTGAACACTCCACGAGTCGTAGTCGCAGGTGGCGGCACAGCTGGGCATATTGAGCCAGCTCTTGCCGTGGCAGAGTCGCT
ACGTCACCGAGGTGCAGAGGTTGTCGCACTTGGCACGACAAAAGGACTGGAAACGTCGATTGTCCCTGAACGCGGATTTG
AACTACGACTGATCAACCCAGTGCCAGTTCCACGAAAAATAAATGCAGATTTGTTCAAGTTGCCGTTTCGGCTATTGGCA
ACAATTTCTCAAACCCGCAAGATTTTAAAAGAATTCGATACCGATGTGGTTATCGGATTCGGCGGATACGTAGCAGCGCC
TGCGTATATTGCAGCAAAACTTCAAAAAATTCCATTTATCGTTCACGAGGCAAACGCCCGCTCCGGTATGGCCAACAAAC
TTGGTGTTCGGCTAGGCGGTATGGGACTTAACGCGGTAGCTAACTCCGGCATGCCAGGAACTGTCGTAGGAATTCCTATC
CGATCGTCATTGTCTGGCGATAACACCGCACTGGATCGAGCACAACAACTGTGGGGGCTAGATCCAGAGAAAAAGACAAT
CTTGATCACCGGTGGTTCCCAAGGCGCCCGTTCCATTAACGCTGCGGTGGCAGAAGGCATCGATGCAGTATTAGCTGATC
CAGACGTTCAAGTTCTTCACGCATATGGGCGTAAGAATTCTGCTCCCGAGGCACAAGAACGATATGTGCCAGTGGCATAT
ATCGACGATATGGCCGCCGCCTATGCCATTGCTGATCTCGTGATCGGTCGCAGTGGAGCAATGACGGTAGCGGAAAATAC
GGCTGCCGGAATTCCTGCTATTTATGTGCCATTACCACACGGTAATGGTGAGCAAGGGCTTAATGCACAACCGTTAGTGG
AGGAAGGCGCAGCGGTATTGGTTGCGGATTCTGAATTTAATGGCGAGGCTTTTAGCTCATTGGCCGCCAAAATTTTAGGC
GATCAAGAAACCTACAACACGATGGTCATCGCAGCTAAGGAATCTGGCACCGCTAACGCTGCGGAGACGATTGCTGACAT
CATCTATTCCATTGTGAAAAATCACGATCGCAACAAATAA

Upstream 100 bases:

>100_bases
GACCGCGATAGAACTGGTAGCGTCGACAAGCAGCGGGGAGCACAGCGCCAACCTCGACGTCGAAATTATCCACAAGACAA
CAAACGCAGGAGAAGATGAA

Downstream 100 bases:

>100_bases
AACAGAAGAGATAGAACATGAATTCAATCGACTTAAGCCGTGTCCACATGATCGGAATCGGTGGAGCGGGAATGTCGGGA
GTAGCGCGCATTTTGTTGTC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MNTPRVVVAGGGTAGHIEPALAVAESLRHRGAEVVALGTTKGLETSIVPERGFELRLINPVPVPRKINADLFKLPFRLLA
TISQTRKILKEFDTDVVIGFGGYVAAPAYIAAKLQKIPFIVHEANARSGMANKLGVRLGGMGLNAVANSGMPGTVVGIPI
RSSLSGDNTALDRAQQLWGLDPEKKTILITGGSQGARSINAAVAEGIDAVLADPDVQVLHAYGRKNSAPEAQERYVPVAY
IDDMAAAYAIADLVIGRSGAMTVAENTAAGIPAIYVPLPHGNGEQGLNAQPLVEEGAAVLVADSEFNGEAFSSLAAKILG
DQETYNTMVIAAKESGTANAAETIADIIYSIVKNHDRNK

Sequences:

>Translated_359_residues
MNTPRVVVAGGGTAGHIEPALAVAESLRHRGAEVVALGTTKGLETSIVPERGFELRLINPVPVPRKINADLFKLPFRLLA
TISQTRKILKEFDTDVVIGFGGYVAAPAYIAAKLQKIPFIVHEANARSGMANKLGVRLGGMGLNAVANSGMPGTVVGIPI
RSSLSGDNTALDRAQQLWGLDPEKKTILITGGSQGARSINAAVAEGIDAVLADPDVQVLHAYGRKNSAPEAQERYVPVAY
IDDMAAAYAIADLVIGRSGAMTVAENTAAGIPAIYVPLPHGNGEQGLNAQPLVEEGAAVLVADSEFNGEAFSSLAAKILG
DQETYNTMVIAAKESGTANAAETIADIIYSIVKNHDRNK
>Mature_359_residues
MNTPRVVVAGGGTAGHIEPALAVAESLRHRGAEVVALGTTKGLETSIVPERGFELRLINPVPVPRKINADLFKLPFRLLA
TISQTRKILKEFDTDVVIGFGGYVAAPAYIAAKLQKIPFIVHEANARSGMANKLGVRLGGMGLNAVANSGMPGTVVGIPI
RSSLSGDNTALDRAQQLWGLDPEKKTILITGGSQGARSINAAVAEGIDAVLADPDVQVLHAYGRKNSAPEAQERYVPVAY
IDDMAAAYAIADLVIGRSGAMTVAENTAAGIPAIYVPLPHGNGEQGLNAQPLVEEGAAVLVADSEFNGEAFSSLAAKILG
DQETYNTMVIAAKESGTANAAETIADIIYSIVKNHDRNK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=356, Percent_Identity=34.8314606741573, Blast_Score=187, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_CORDI (Q6NGC8)

Other databases:

- EMBL:   BX248358
- RefSeq:   NP_939940.1
- ProteinModelPortal:   Q6NGC8
- SMR:   Q6NGC8
- GeneID:   2650787
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1598
- NMPDR:   fig|257309.1.peg.1531
- HOGENOM:   HBG617076
- OMA:   PHGNGEQ
- PhylomeDB:   Q6NGC8
- ProtClustDB:   PRK00726
- BioCyc:   CDIP257309:DIP1598-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37505; Mature: 37505

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPRVVVAGGGTAGHIEPALAVAESLRHRGAEVVALGTTKGLETSIVPERGFELRLINP
CCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEECC
VPVPRKINADLFKLPFRLLATISQTRKILKEFDTDVVIGFGGYVAAPAYIAAKLQKIPFI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCEE
VHEANARSGMANKLGVRLGGMGLNAVANSGMPGTVVGIPIRSSLSGDNTALDRAQQLWGL
EEECCCCCCCCHHHCEEECCCCHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCC
DPEKKTILITGGSQGARSINAAVAEGIDAVLADPDVQVLHAYGRKNSAPEAQERYVPVAY
CCCCCEEEEECCCCCCHHHHHHHHHCCHHHHCCCCHHHHEECCCCCCCCCHHHCCCCEEH
IDDMAAAYAIADLVIGRSGAMTVAENTAAGIPAIYVPLPHGNGEQGLNAQPLVEEGAAVL
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCHHHCCCEEE
VADSEFNGEAFSSLAAKILGDQETYNTMVIAAKESGTANAAETIADIIYSIVKNHDRNK
EECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNTPRVVVAGGGTAGHIEPALAVAESLRHRGAEVVALGTTKGLETSIVPERGFELRLINP
CCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEECC
VPVPRKINADLFKLPFRLLATISQTRKILKEFDTDVVIGFGGYVAAPAYIAAKLQKIPFI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCEE
VHEANARSGMANKLGVRLGGMGLNAVANSGMPGTVVGIPIRSSLSGDNTALDRAQQLWGL
EEECCCCCCCCHHHCEEECCCCHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCC
DPEKKTILITGGSQGARSINAAVAEGIDAVLADPDVQVLHAYGRKNSAPEAQERYVPVAY
CCCCCEEEEECCCCCCHHHHHHHHHCCHHHHCCCCHHHHEECCCCCCCCCHHHCCCCEEH
IDDMAAAYAIADLVIGRSGAMTVAENTAAGIPAIYVPLPHGNGEQGLNAQPLVEEGAAVL
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCHHHCCCEEE
VADSEFNGEAFSSLAAKILGDQETYNTMVIAAKESGTANAAETIADIIYSIVKNHDRNK
EECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14602910