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The map label for this gene is impA [H]

Identifier: 38234134

GI number: 38234134

Start: 1587026

End: 1587811

Strand: Reverse

Name: impA [H]

Synonym: DIP1559

Alternate gene names: 38234134

Gene position: 1587811-1587026 (Counterclockwise)

Preceding gene: 38234135

Following gene: 38234133

Centisome position: 63.8

GC content: 50.13

Gene sequence:

>786_bases
ATGACCGATGTTCGGGACCTTTATCATATTGCAGAGGCAATACTCGATGATGCCGAGCGTCTATTCATTCAGGGCATAGG
TTCAGCTCCTACAACGTTTAAAAACGGCGGTGATTTTGCCACCGATATGGATCTGAAAATCGAGCAATATCTGCGCACCC
AACTGGTCATGATGACTGGAATTCCTGTTTTTGGTGAGGAATACGGTGGAAAGCTAGGAACACCCATGTGGGTGGTTGAC
CCTATCGATGGCACTGCCAACTATGCGGCAGGCAATCCTATGTCATCGATATTGATAAGTCTCATTGCGGATGGGGAGCC
CGTTATCGGGCTGACCTCAGTTCCTATGGTCGGACAGCGTTTCGGTGCGTACGCTGATTCACCATTGTTACTGAATGGCC
AGGTTCAACCCCAAATGAATGCTCGGGACCAACGCCATGTTTCCCACGTTGGATTCACATCGATCGCCTCGCCACGAGAA
TCGTCGTTTCCTACGGTTGTTCGCCAAGGTCTATTAGGTGCCCTAGCACAAACATATCTACGGCCGCGTATCACAGGATC
AGTAGGAATTGATTTAGCGTATGCGGCTGCAGGCATTTTTGATGCGGCTTTGAGCCTAAGCCCCAATCTATGGGATAACG
CTGCAGGCATCATGCTTGTTCGTGCGGCTGGGGGAGTAGTTACTGACCTTGATGGCAATCAGTGGACTCCTACCTCACAG
GGGGTAATTGTAGGTTCGGCCCAATCCCATGAAGTGTTGATGGCTACCATTGACACAATGAGATAG

Upstream 100 bases:

>100_bases
TGGAGCTTGCGCGATATGAAGACGAAGGTATTGATTCTGCCATTATTGGCAAAGCGCTGTATGAAGGCCGTTTTACCCTT
AAGGAGGCGCTCGCCGCGCT

Downstream 100 bases:

>100_bases
CTATCTCGCGTTACTTTTCCGGCTGTTGTTTGACAAAAGTTACGCAGTTTTAAGTCCCTATGAATTTGTTTCACACAAGG
AGCTAACACCATGCCAGTCG

Product: inositol monophosphate phosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTDVRDLYHIAEAILDDAERLFIQGIGSAPTTFKNGGDFATDMDLKIEQYLRTQLVMMTGIPVFGEEYGGKLGTPMWVVD
PIDGTANYAAGNPMSSILISLIADGEPVIGLTSVPMVGQRFGAYADSPLLLNGQVQPQMNARDQRHVSHVGFTSIASPRE
SSFPTVVRQGLLGALAQTYLRPRITGSVGIDLAYAAAGIFDAALSLSPNLWDNAAGIMLVRAAGGVVTDLDGNQWTPTSQ
GVIVGSAQSHEVLMATIDTMR

Sequences:

>Translated_261_residues
MTDVRDLYHIAEAILDDAERLFIQGIGSAPTTFKNGGDFATDMDLKIEQYLRTQLVMMTGIPVFGEEYGGKLGTPMWVVD
PIDGTANYAAGNPMSSILISLIADGEPVIGLTSVPMVGQRFGAYADSPLLLNGQVQPQMNARDQRHVSHVGFTSIASPRE
SSFPTVVRQGLLGALAQTYLRPRITGSVGIDLAYAAAGIFDAALSLSPNLWDNAAGIMLVRAAGGVVTDLDGNQWTPTSQ
GVIVGSAQSHEVLMATIDTMR
>Mature_260_residues
TDVRDLYHIAEAILDDAERLFIQGIGSAPTTFKNGGDFATDMDLKIEQYLRTQLVMMTGIPVFGEEYGGKLGTPMWVVDP
IDGTANYAAGNPMSSILISLIADGEPVIGLTSVPMVGQRFGAYADSPLLLNGQVQPQMNARDQRHVSHVGFTSIASPRES
SFPTVVRQGLLGALAQTYLRPRITGSVGIDLAYAAAGIFDAALSLSPNLWDNAAGIMLVRAAGGVVTDLDGNQWTPTSQG
VIVGSAQSHEVLMATIDTMR

Specific function: Catalyzes the dephosphorylation of inositol-1-phosphate (I-1-P) to yield free myo-inositol, a key metabolite in mycobacteria [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788882, Length=232, Percent_Identity=29.3103448275862, Blast_Score=82, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320493, Length=258, Percent_Identity=25.5813953488372, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357329, Length=261, Percent_Identity=26.8199233716475, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357957, Length=241, Percent_Identity=27.3858921161826, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24664926, Length=256, Percent_Identity=25.390625, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24664922, Length=250, Percent_Identity=26, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 27742; Mature: 27611

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVRDLYHIAEAILDDAERLFIQGIGSAPTTFKNGGDFATDMDLKIEQYLRTQLVMMTG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHC
IPVFGEEYGGKLGTPMWVVDPIDGTANYAAGNPMSSILISLIADGEPVIGLTSVPMVGQR
CCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHH
FGAYADSPLLLNGQVQPQMNARDQRHVSHVGFTSIASPRESSFPTVVRQGLLGALAQTYL
HCCCCCCCEEECCCCCCCCCCHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RPRITGSVGIDLAYAAAGIFDAALSLSPNLWDNAAGIMLVRAAGGVVTDLDGNQWTPTSQ
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCC
GVIVGSAQSHEVLMATIDTMR
CEEEECCCCCEEEEEEHHHCC
>Mature Secondary Structure 
TDVRDLYHIAEAILDDAERLFIQGIGSAPTTFKNGGDFATDMDLKIEQYLRTQLVMMTG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHC
IPVFGEEYGGKLGTPMWVVDPIDGTANYAAGNPMSSILISLIADGEPVIGLTSVPMVGQR
CCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHH
FGAYADSPLLLNGQVQPQMNARDQRHVSHVGFTSIASPRESSFPTVVRQGLLGALAQTYL
HCCCCCCCEEECCCCCCCCCCHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RPRITGSVGIDLAYAAAGIFDAALSLSPNLWDNAAGIMLVRAAGGVVTDLDGNQWTPTSQ
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCC
GVIVGSAQSHEVLMATIDTMR
CEEEECCCCCEEEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]