Click here to switch to the map view.

The map label for this gene is nrdR

Identifier: 38234009

GI number: 38234009

Start: 1445404

End: 1445859

Strand: Reverse

Name: nrdR

Synonym: DIP1424

Alternate gene names: 38234009

Gene position: 1445859-1445404 (Counterclockwise)

Preceding gene: 38234010

Following gene: 38234007

Centisome position: 58.1

GC content: 46.27

Gene sequence:

>456_bases
GTGTACTGTCCTTTTTGTCATAATGATCAGTCTCGTGTGATCGACTCTCGTGTGATTGATTCAGGTTCGGCGATTAGAAG
ACGTCGCGAATGTACACAGTGTAAGAACCGGTTTACTACAGTTGAAAAAGCACAACTCTTAGTGGTCAAACGCAATGGGC
TTACCGAGCCTTTTAGTAGGGAAAAGGTTATCGTAGGTGTCCGTCGTGCATGCCAAGGCCGAGATGTAAGTGATGATGCA
TTGAAACGGCTTGCGCAACAAGTAGAAGAGCGAGTTCGTTTGCATGGCAGCTCACAGATTCACGCTAACGAGATAGGTCT
TGCCATTTTGGAGCCACTGCGGGAACTAGATGAAGTAGCTTATCTGCGGTTTGCATCAGTATATAAATCGTTTGAAAGCG
CTGATGATTTCGAATCTGAGATTCGGTTGATGCGACGGCGGGATAGGTCGAATTAG

Upstream 100 bases:

>100_bases
TAATGAAAGATTGCGTTGTAGTAAATTTCCGCGCTATTTCGGGGCACGCTATAAGATGTGAGAGTCTGTTTTAGTAGCGA
GGAATAAGCGGGGTTGTGTC

Downstream 100 bases:

>100_bases
CCTCAAGAAAATAAGCAGTGGTTCCTACTCTCTGCTCTACAAGCAGTAGGAACCACTGCTTATTAAAGAGCTTCAATGAG
CTTATGGATCTTTCGTTCCG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MYCPFCHNDQSRVIDSRVIDSGSAIRRRRECTQCKNRFTTVEKAQLLVVKRNGLTEPFSREKVIVGVRRACQGRDVSDDA
LKRLAQQVEERVRLHGSSQIHANEIGLAILEPLRELDEVAYLRFASVYKSFESADDFESEIRLMRRRDRSN

Sequences:

>Translated_151_residues
MYCPFCHNDQSRVIDSRVIDSGSAIRRRRECTQCKNRFTTVEKAQLLVVKRNGLTEPFSREKVIVGVRRACQGRDVSDDA
LKRLAQQVEERVRLHGSSQIHANEIGLAILEPLRELDEVAYLRFASVYKSFESADDFESEIRLMRRRDRSN
>Mature_151_residues
MYCPFCHNDQSRVIDSRVIDSGSAIRRRRECTQCKNRFTTVEKAQLLVVKRNGLTEPFSREKVIVGVRRACQGRDVSDDA
LKRLAQQVEERVRLHGSSQIHANEIGLAILEPLRELDEVAYLRFASVYKSFESADDFESEIRLMRRRDRSN

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=144, Percent_Identity=44.4444444444444, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_CORDI (Q6NGS9)

Other databases:

- EMBL:   BX248358
- RefSeq:   NP_939776.1
- GeneID:   2649698
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1424
- NMPDR:   fig|257309.1.peg.1367
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q6NGS9
- ProtClustDB:   PRK00464
- BioCyc:   CDIP257309:DIP1424-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17515; Mature: 17515

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYCPFCHNDQSRVIDSRVIDSGSAIRRRRECTQCKNRFTTVEKAQLLVVKRNGLTEPFSR
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCCCCCCC
EKVIVGVRRACQGRDVSDDALKRLAQQVEERVRLHGSSQIHANEIGLAILEPLRELDEVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
YLRFASVYKSFESADDFESEIRLMRRRDRSN
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYCPFCHNDQSRVIDSRVIDSGSAIRRRRECTQCKNRFTTVEKAQLLVVKRNGLTEPFSR
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCCCCCCC
EKVIVGVRRACQGRDVSDDALKRLAQQVEERVRLHGSSQIHANEIGLAILEPLRELDEVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
YLRFASVYKSFESADDFESEIRLMRRRDRSN
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910