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The map label for this gene is ygcA [C]

Identifier: 38233983

GI number: 38233983

Start: 1416837

End: 1418099

Strand: Reverse

Name: ygcA [C]

Synonym: DIP1398

Alternate gene names: 38233983

Gene position: 1418099-1416837 (Counterclockwise)

Preceding gene: 38233984

Following gene: 38233982

Centisome position: 56.98

GC content: 48.06

Gene sequence:

>1263_bases
ATGACAAAAGACCAGCAAAACATTGAACGCGGAAGCGTTATAAATGTTGAAATTCTTAATGCTGCACATGGCGGACAGGG
AATTGCTAAATACGATGGACGAGTAATATTCGTAAAAGGCGCCTTCCCAGGGGATCGGCTCAGTGCAAATATCACTCATG
TGAAAAAGAAGTTTGCTCGGGCTACGATCGCGTCGATCGAAATGCCCTCACCACTTCGAATGCAGCAACGATGCCTAGCT
GCTGCGAATGGTGCTGGCTGCTGTGATTTTGGTGAGTTCGATCCAGAAATTGAGGGCCGGTACAAAGCTGATTTAGTTCT
TGAACAATTGGAGAGACTCGGAAAGGTCTCCCAGCCTCCAACATGTGAAGTTGTATCATTCGGTTCTCCTACTCAGTGGC
GAACCCGCATGCGTTTAGGTGTTGATGCTCAGGGCAGAGCAGGAGGATTTGCTAGCCAGTCACGTGAAGTCGTCTCAGGA
GTGCCATGTAGTCAAGGCGTAATGGGGTTGCTTGATGGCATAGTAGGTGCGGAACAGAACGTATTACGTTTTACTCCAGG
ATCTCAAGTAGTAGTTGTTTGTGATGATCTCGGTCAGCGCACTGTCGTTGAGACTCAACCAGCGCCCCGCGGTAAACGTA
CCGAGTCGATGGTAAAAGTTGTAGAGGGTACTGGCAAAGTTTCCCAAGTTGTTGATGGCGTCACATTTGAACTCCCTGCT
ACTGGATTTTGGCAATCTCACAAAGATGCGGCTCAAGCATATGCAGACACTATTCGGGAATGGTTTGGATCTCTAATAAT
TCGGAATACAGATTCATCACTGGTTGCGTGGGATCTCTATGGCGGATGTGGTTCTTTTGCTTCGGCGATTTTATCGGCAG
TTGATAATCATGGTGTTGTCCATTGTGTAGAAAGCGCGCCGGCTGCAGTTTCGGCTGGCAAACGAGCTCTTTCTCAACTG
GTGGAGGATCAAAAAATAGTTTTCCACACAGAAACAGTTGAGCGGGCCATGAATCAACTGCCTGCCCCTACCCTCGTTGT
ATTAGATCCACCTCGAGTAGGTGCTGGTGCTGAAACAGTACGAGCTATTGCACAATCGGGACCACAGGCTGCAATACACA
TCGGTTGTGACCCTGCCACGTTTGCTCGTGACATCGCCGAATGGAGCCGAAACGGTTTTATTTTGGAAAAACTTCGTGTA
TTCGATGCGTTTCCCGGTACGCATCACTGCGAAACCATCGGTTTATTAACAAAGAAAAACTAA

Upstream 100 bases:

>100_bases
GCAAAACTGATGTATTAAATGGTGACACGCGCCAATCAGGCGGTCAATGACTTCTTAGATTCGACGTCCACCGCTCCACT
AGACGAAGAAAAAGAACGAT

Downstream 100 bases:

>100_bases
TTAGATTAGAGGGACTTTGCTGCTAGAGTCTTGGCAGTGCGTTACGCAGAGTACACTTGTTGTCAAGACTTTATTCGATA
TCTTTGATCTTTCTGTTGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MTKDQQNIERGSVINVEILNAAHGGQGIAKYDGRVIFVKGAFPGDRLSANITHVKKKFARATIASIEMPSPLRMQQRCLA
AANGAGCCDFGEFDPEIEGRYKADLVLEQLERLGKVSQPPTCEVVSFGSPTQWRTRMRLGVDAQGRAGGFASQSREVVSG
VPCSQGVMGLLDGIVGAEQNVLRFTPGSQVVVVCDDLGQRTVVETQPAPRGKRTESMVKVVEGTGKVSQVVDGVTFELPA
TGFWQSHKDAAQAYADTIREWFGSLIIRNTDSSLVAWDLYGGCGSFASAILSAVDNHGVVHCVESAPAAVSAGKRALSQL
VEDQKIVFHTETVERAMNQLPAPTLVVLDPPRVGAGAETVRAIAQSGPQAAIHIGCDPATFARDIAEWSRNGFILEKLRV
FDAFPGTHHCETIGLLTKKN

Sequences:

>Translated_420_residues
MTKDQQNIERGSVINVEILNAAHGGQGIAKYDGRVIFVKGAFPGDRLSANITHVKKKFARATIASIEMPSPLRMQQRCLA
AANGAGCCDFGEFDPEIEGRYKADLVLEQLERLGKVSQPPTCEVVSFGSPTQWRTRMRLGVDAQGRAGGFASQSREVVSG
VPCSQGVMGLLDGIVGAEQNVLRFTPGSQVVVVCDDLGQRTVVETQPAPRGKRTESMVKVVEGTGKVSQVVDGVTFELPA
TGFWQSHKDAAQAYADTIREWFGSLIIRNTDSSLVAWDLYGGCGSFASAILSAVDNHGVVHCVESAPAAVSAGKRALSQL
VEDQKIVFHTETVERAMNQLPAPTLVVLDPPRVGAGAETVRAIAQSGPQAAIHIGCDPATFARDIAEWSRNGFILEKLRV
FDAFPGTHHCETIGLLTKKN
>Mature_419_residues
TKDQQNIERGSVINVEILNAAHGGQGIAKYDGRVIFVKGAFPGDRLSANITHVKKKFARATIASIEMPSPLRMQQRCLAA
ANGAGCCDFGEFDPEIEGRYKADLVLEQLERLGKVSQPPTCEVVSFGSPTQWRTRMRLGVDAQGRAGGFASQSREVVSGV
PCSQGVMGLLDGIVGAEQNVLRFTPGSQVVVVCDDLGQRTVVETQPAPRGKRTESMVKVVEGTGKVSQVVDGVTFELPAT
GFWQSHKDAAQAYADTIREWFGSLIIRNTDSSLVAWDLYGGCGSFASAILSAVDNHGVVHCVESAPAAVSAGKRALSQLV
EDQKIVFHTETVERAMNQLPAPTLVVLDPPRVGAGAETVRAIAQSGPQAAIHIGCDPATFARDIAEWSRNGFILEKLRVF
DAFPGTHHCETIGLLTKKN

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain

Homologues:

Organism=Escherichia coli, GI1789148, Length=439, Percent_Identity=22.7790432801822, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787083, Length=205, Percent_Identity=27.3170731707317, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1398_CORDI (Q6NGV2)

Other databases:

- EMBL:   BX248358
- RefSeq:   NP_939750.1
- ProteinModelPortal:   Q6NGV2
- GeneID:   2649473
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1398
- NMPDR:   fig|257309.1.peg.1341
- HOGENOM:   HBG690163
- OMA:   HASTADR
- ProtClustDB:   CLSK633522
- BioCyc:   CDIP257309:DIP1398-MONOMER
- InterPro:   IPR016027
- InterPro:   IPR002792
- InterPro:   IPR010280

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 44996; Mature: 44864

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50926 TRAM; PS01230 TRMA_1; PS01231 TRMA_2

Important sites: ACT_SITE 376-376 BINDING 245-245 BINDING 280-280 BINDING 304-304 BINDING 349-349

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKDQQNIERGSVINVEILNAAHGGQGIAKYDGRVIFVKGAFPGDRLSANITHVKKKFAR
CCCCHHCCCCCCEEEEEEEECCCCCCCEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHH
ATIASIEMPSPLRMQQRCLAAANGAGCCDFGEFDPEIEGRYKADLVLEQLERLGKVSQPP
HHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
TCEVVSFGSPTQWRTRMRLGVDAQGRAGGFASQSREVVSGVPCSQGVMGLLDGIVGAEQN
CEEEEECCCCHHHHHHHEECCCCCCCCCCCCHHCHHHHCCCCHHHHHHHHHHHHHCCCCC
VLRFTPGSQVVVVCDDLGQRTVVETQPAPRGKRTESMVKVVEGTGKVSQVVDGVTFELPA
EEEECCCCEEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHCCCEEECCC
TGFWQSHKDAAQAYADTIREWFGSLIIRNTDSSLVAWDLYGGCGSFASAILSAVDNHGVV
CCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCEE
HCVESAPAAVSAGKRALSQLVEDQKIVFHTETVERAMNQLPAPTLVVLDPPRVGAGAETV
EEECCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCEEEEECCCCCCCCHHHH
RAIAQSGPQAAIHIGCDPATFARDIAEWSRNGFILEKLRVFDAFPGTHHCETIGLLTKKN
HHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
TKDQQNIERGSVINVEILNAAHGGQGIAKYDGRVIFVKGAFPGDRLSANITHVKKKFAR
CCCHHCCCCCCEEEEEEEECCCCCCCEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHH
ATIASIEMPSPLRMQQRCLAAANGAGCCDFGEFDPEIEGRYKADLVLEQLERLGKVSQPP
HHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
TCEVVSFGSPTQWRTRMRLGVDAQGRAGGFASQSREVVSGVPCSQGVMGLLDGIVGAEQN
CEEEEECCCCHHHHHHHEECCCCCCCCCCCCHHCHHHHCCCCHHHHHHHHHHHHHCCCCC
VLRFTPGSQVVVVCDDLGQRTVVETQPAPRGKRTESMVKVVEGTGKVSQVVDGVTFELPA
EEEECCCCEEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHCCCEEECCC
TGFWQSHKDAAQAYADTIREWFGSLIIRNTDSSLVAWDLYGGCGSFASAILSAVDNHGVV
CCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCEE
HCVESAPAAVSAGKRALSQLVEDQKIVFHTETVERAMNQLPAPTLVVLDPPRVGAGAETV
EEECCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCEEEEECCCCCCCCHHHH
RAIAQSGPQAAIHIGCDPATFARDIAEWSRNGFILEKLRVFDAFPGTHHCETIGLLTKKN
HHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14602910