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The map label for this gene is bioW [H]

Identifier: 38233966

GI number: 38233966

Start: 1398642

End: 1399385

Strand: Direct

Name: bioW [H]

Synonym: DIP1381

Alternate gene names: 38233966

Gene position: 1398642-1399385 (Clockwise)

Preceding gene: 38233965

Following gene: 38233967

Centisome position: 56.2

GC content: 49.19

Gene sequence:

>744_bases
TTGCTTTATGCTTCCTATATGAGCTATGTCAGCATCAAAATGCATGCGAGCAGCAACGGAGCCCACATCTCTGGAGCTGA
AACTCTTGTTGATGAATCACGGGCCTATGAATTTTTGTCCAGCTTTTATCAGCGTGCAAATACGCATTCCAAGGGGAAAC
CGGAGATCACCACGCTGACAATCCGCAGAATTAAGGATGCAGATATCATCACAATCCCTGCATTAGAGGTCAAATGCCTT
CCTGCTCTGCATCCTAGCGAAGCCCACCGTCAAGTAATCGAGCAACTTTCCAACGTCGTTAGTCCAACAATCGCGCAGAT
GGCACTTCATACAGTCTTGAACGCTCGCAACATGCGTGGAGCAATTCTGCTGTGTGCGCACACTGGACAACGCCTCGATC
CCTACGATCCACAACGAGGAGTCCGCGCATCGACGTTTGGGGTCACACCACAAGAGTCCGCTGGCCCAACACTTAACAAG
TCACACTTCAACGAAGCCCTAGTCTTAGCGTCCAAAGTGATGAGCGCGCCGGGCATCGTCGCAGAAATATGCATCTCCGA
CGATCCTGCCTATACAACGGGATACGTCACAACAGAAAATACCTACATCCGTATTCCTCACATGAAAGATCCCTATTCTC
CCATCGGCGGGCGTGTTTTTCTATTGGATACTCGGGTGAGCACGCCTGAAGATACGATTAGTTATCTTGAACAAAAGCCA
GTCCTCATTACCGGAGTTAATTAA

Upstream 100 bases:

>100_bases
GGGTTTCTATCAATGTTGAGGCACGCAGCTCGACAAAAATGCCGTGACATCGGAAAGTTTGTGGAAATTATTTCAATAAA
ATTGAACACTGTTTAACTCA

Downstream 100 bases:

>100_bases
TGTCTCCATCGCTTGATTTTTATGCTCACCAACGCAACGTGGAGTGGCATGAACGAGGACTTGAGCGCACACCCGCGCAG
TTTTATTCACCTCAAACTCC

Product: 6-carboxyhexanoate--CoA ligase

Products: NA

Alternate protein names: Pimeloyl-CoA synthase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MLYASYMSYVSIKMHASSNGAHISGAETLVDESRAYEFLSSFYQRANTHSKGKPEITTLTIRRIKDADIITIPALEVKCL
PALHPSEAHRQVIEQLSNVVSPTIAQMALHTVLNARNMRGAILLCAHTGQRLDPYDPQRGVRASTFGVTPQESAGPTLNK
SHFNEALVLASKVMSAPGIVAEICISDDPAYTTGYVTTENTYIRIPHMKDPYSPIGGRVFLLDTRVSTPEDTISYLEQKP
VLITGVN

Sequences:

>Translated_247_residues
MLYASYMSYVSIKMHASSNGAHISGAETLVDESRAYEFLSSFYQRANTHSKGKPEITTLTIRRIKDADIITIPALEVKCL
PALHPSEAHRQVIEQLSNVVSPTIAQMALHTVLNARNMRGAILLCAHTGQRLDPYDPQRGVRASTFGVTPQESAGPTLNK
SHFNEALVLASKVMSAPGIVAEICISDDPAYTTGYVTTENTYIRIPHMKDPYSPIGGRVFLLDTRVSTPEDTISYLEQKP
VLITGVN
>Mature_247_residues
MLYASYMSYVSIKMHASSNGAHISGAETLVDESRAYEFLSSFYQRANTHSKGKPEITTLTIRRIKDADIITIPALEVKCL
PALHPSEAHRQVIEQLSNVVSPTIAQMALHTVLNARNMRGAILLCAHTGQRLDPYDPQRGVRASTFGVTPQESAGPTLNK
SHFNEALVLASKVMSAPGIVAEICISDDPAYTTGYVTTENTYIRIPHMKDPYSPIGGRVFLLDTRVSTPEDTISYLEQKP
VLITGVN

Specific function: Transforms pimelate into pimeloyl-CoA [H]

COG id: COG1424

COG function: function code H; Pimeloyl-CoA synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BioW family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005499
- ProDom:   PD017229 [H]

Pfam domain/function: PF03744 BioW [H]

EC number: =6.2.1.14 [H]

Molecular weight: Translated: 27073; Mature: 27073

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYASYMSYVSIKMHASSNGAHISGAETLVDESRAYEFLSSFYQRANTHSKGKPEITTLT
CEEHHEEEEEEEEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IRRIKDADIITIPALEVKCLPALHPSEAHRQVIEQLSNVVSPTIAQMALHTVLNARNMRG
EEEECCCCEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCC
AILLCAHTGQRLDPYDPQRGVRASTFGVTPQESAGPTLNKSHFNEALVLASKVMSAPGIV
EEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCE
AEICISDDPAYTTGYVTTENTYIRIPHMKDPYSPIGGRVFLLDTRVSTPEDTISYLEQKP
EEEEECCCCCCEEEEEEECCEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCC
VLITGVN
EEEEECC
>Mature Secondary Structure
MLYASYMSYVSIKMHASSNGAHISGAETLVDESRAYEFLSSFYQRANTHSKGKPEITTLT
CEEHHEEEEEEEEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IRRIKDADIITIPALEVKCLPALHPSEAHRQVIEQLSNVVSPTIAQMALHTVLNARNMRG
EEEECCCCEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCC
AILLCAHTGQRLDPYDPQRGVRASTFGVTPQESAGPTLNKSHFNEALVLASKVMSAPGIV
EEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCE
AEICISDDPAYTTGYVTTENTYIRIPHMKDPYSPIGGRVFLLDTRVSTPEDTISYLEQKP
EEEEECCCCCCEEEEEEECCEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCC
VLITGVN
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2110099; 1445232 [H]