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The map label for this gene is ruvB

Identifier: 38233960

GI number: 38233960

Start: 1392938

End: 1394026

Strand: Reverse

Name: ruvB

Synonym: DIP1375

Alternate gene names: 38233960

Gene position: 1394026-1392938 (Counterclockwise)

Preceding gene: 38233961

Following gene: 38233959

Centisome position: 56.02

GC content: 50.05

Gene sequence:

>1089_bases
GTGGCTAATATTGAAAAAACCGAGTTTCATGTCCCAGCACCGGTATCTGCTGCTGGGAATCAGAAAAGCTCACTGGGCAA
TGCTGATGTCGATGCACGATTGCAATCCAATGAAGGGGAAGTAGAGACTTCGCTTCGTCCACGTAGTTTGGACGAATTCA
TTGGACAGCCAAAGGTGAGAGATCAGCTCAATCTTGTCTTATCAGGTGCTAAGAGCCGAGGAGTTGCACCAGACCATGTG
TTACTTTCGGGACCGCCTGGACTAGGAAAAACAACAATGGCGATGATTATTGCCTATGAATTAGGCACTAGTCTTCGTAT
GACATCCGGCCCTGCATTGGAACGCGCCGGTGATCTAGCAGCCATGCTGTCTAATTTGATGGAAGGTGATGTCTTATTTA
TCGATGAGATACACCGTATGGCACGTCCGGCTGAAGAGATGCTGTATATGGCGATGGAGGATTTTAGAATCGATGTCATC
GTCGGTAAAGGGCCTGGGGCAACGTCAATTCCCCTTGAACTAGCTCCTTTTACTCTGGTTGGTGCAACTACACGGTCCGG
AATGCTCACAGGACCATTACGTGATCGATTTGGGTTTACTGCCCAAATGGAATTCTACGAGGTTGAAGATCTCACCAAGG
TTGTCGTACGCGCTGCTGCGGTTTTAGGGGTCAGCATCGATCATGATGCGGCTGTAGAAATAGCCTCCAGATCTCGTGGA
ACACCACGTATAGCAAATCGTCTGCTTCGTCGGGTTCGAGACTTTGCAGAGGTCAACGCCGACGGACATATCAATCTCGC
AGCAGCTCAAGCTGCATTGGTGGTATTCGACGTAGACGAAATGGGGCTCGATCGATTAGACAGAGCTGTGTTGGAAGCGT
TGATAAAGGGCCACGGTGGTGGGCCAGTAGGTATTAATACTCTAGCGCTAGCAGTCGGCGAAGAGCCGTCGACAGTCGAA
GAAGTATGTGAACCATATTTGGTCAGGGCGGGGATGGTTACACGCACTGGCAGAGGCCGAGTAGCCACTGCGACTGCTTG
GCGTCATTTAGGACTTGAACCTCCGGAAGGAATTATTGGTTCGCTATAG

Upstream 100 bases:

>100_bases
CTCGTGTGTTGCGGGACTCCCCAGAGCTCTCAAAATCTCAAGCATTGCGCGCAGCATTAAGCGAATTGGGCACTAAGAAC
TAAATAGGGGAGAGTTATTC

Downstream 100 bases:

>100_bases
TCATTGAGCATGACATCAACTTTACTTTTGTACGTGGCCTTGGTGGTGGTGTTTGTGCTGCCATCACTGCTTATCAGGCG
AAGGCAAAAACAACATTTAG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MANIEKTEFHVPAPVSAAGNQKSSLGNADVDARLQSNEGEVETSLRPRSLDEFIGQPKVRDQLNLVLSGAKSRGVAPDHV
LLSGPPGLGKTTMAMIIAYELGTSLRMTSGPALERAGDLAAMLSNLMEGDVLFIDEIHRMARPAEEMLYMAMEDFRIDVI
VGKGPGATSIPLELAPFTLVGATTRSGMLTGPLRDRFGFTAQMEFYEVEDLTKVVVRAAAVLGVSIDHDAAVEIASRSRG
TPRIANRLLRRVRDFAEVNADGHINLAAAQAALVVFDVDEMGLDRLDRAVLEALIKGHGGGPVGINTLALAVGEEPSTVE
EVCEPYLVRAGMVTRTGRGRVATATAWRHLGLEPPEGIIGSL

Sequences:

>Translated_362_residues
MANIEKTEFHVPAPVSAAGNQKSSLGNADVDARLQSNEGEVETSLRPRSLDEFIGQPKVRDQLNLVLSGAKSRGVAPDHV
LLSGPPGLGKTTMAMIIAYELGTSLRMTSGPALERAGDLAAMLSNLMEGDVLFIDEIHRMARPAEEMLYMAMEDFRIDVI
VGKGPGATSIPLELAPFTLVGATTRSGMLTGPLRDRFGFTAQMEFYEVEDLTKVVVRAAAVLGVSIDHDAAVEIASRSRG
TPRIANRLLRRVRDFAEVNADGHINLAAAQAALVVFDVDEMGLDRLDRAVLEALIKGHGGGPVGINTLALAVGEEPSTVE
EVCEPYLVRAGMVTRTGRGRVATATAWRHLGLEPPEGIIGSL
>Mature_361_residues
ANIEKTEFHVPAPVSAAGNQKSSLGNADVDARLQSNEGEVETSLRPRSLDEFIGQPKVRDQLNLVLSGAKSRGVAPDHVL
LSGPPGLGKTTMAMIIAYELGTSLRMTSGPALERAGDLAAMLSNLMEGDVLFIDEIHRMARPAEEMLYMAMEDFRIDVIV
GKGPGATSIPLELAPFTLVGATTRSGMLTGPLRDRFGFTAQMEFYEVEDLTKVVVRAAAVLGVSIDHDAAVEIASRSRGT
PRIANRLLRRVRDFAEVNADGHINLAAAQAALVVFDVDEMGLDRLDRAVLEALIKGHGGGPVGINTLALAVGEEPSTVEE
VCEPYLVRAGMVTRTGRGRVATATAWRHLGLEPPEGIIGSL

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=319, Percent_Identity=56.1128526645768, Blast_Score=373, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_CORDI (P61530)

Other databases:

- EMBL:   BX248358
- RefSeq:   NP_939727.1
- ProteinModelPortal:   P61530
- SMR:   P61530
- GeneID:   2649906
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1375
- NMPDR:   fig|257309.1.peg.1318
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   P61530
- ProtClustDB:   PRK00080
- BioCyc:   CDIP257309:DIP1375-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38596; Mature: 38465

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIEKTEFHVPAPVSAAGNQKSSLGNADVDARLQSNEGEVETSLRPRSLDEFIGQPKVR
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCCCCHHHHHCCCCHH
DQLNLVLSGAKSRGVAPDHVLLSGPPGLGKTTMAMIIAYELGTSLRMTSGPALERAGDLA
HHHHHHEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHH
AMLSNLMEGDVLFIDEIHRMARPAEEMLYMAMEDFRIDVIVGKGPGATSIPLELAPFTLV
HHHHHHHCCCEEEHHHHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEEECCEEEE
GATTRSGMLTGPLRDRFGFTAQMEFYEVEDLTKVVVRAAAVLGVSIDHDAAVEIASRSRG
ECCCCCCEEECCHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCC
TPRIANRLLRRVRDFAEVNADGHINLAAAQAALVVFDVDEMGLDRLDRAVLEALIKGHGG
CHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEECHHHCHHHHHHHHHHHHHHCCCC
GPVGINTLALAVGEEPSTVEEVCEPYLVRAGMVTRTGRGRVATATAWRHLGLEPPEGIIG
CCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCEEEHHHHHHCCCCCCCHHCC
SL
CC
>Mature Secondary Structure 
ANIEKTEFHVPAPVSAAGNQKSSLGNADVDARLQSNEGEVETSLRPRSLDEFIGQPKVR
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCCCCHHHHHCCCCHH
DQLNLVLSGAKSRGVAPDHVLLSGPPGLGKTTMAMIIAYELGTSLRMTSGPALERAGDLA
HHHHHHEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHH
AMLSNLMEGDVLFIDEIHRMARPAEEMLYMAMEDFRIDVIVGKGPGATSIPLELAPFTLV
HHHHHHHCCCEEEHHHHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEEECCEEEE
GATTRSGMLTGPLRDRFGFTAQMEFYEVEDLTKVVVRAAAVLGVSIDHDAAVEIASRSRG
ECCCCCCEEECCHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCC
TPRIANRLLRRVRDFAEVNADGHINLAAAQAALVVFDVDEMGLDRLDRAVLEALIKGHGG
CHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEECHHHCHHHHHHHHHHHHHHCCCC
GPVGINTLALAVGEEPSTVEEVCEPYLVRAGMVTRTGRGRVATATAWRHLGLEPPEGIIG
CCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCEEEHHHHHHCCCCCCCHHCC
SL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910