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The map label for this gene is ruvA

Identifier: 38233961

GI number: 38233961

Start: 1394044

End: 1394655

Strand: Reverse

Name: ruvA

Synonym: DIP1376

Alternate gene names: 38233961

Gene position: 1394655-1394044 (Counterclockwise)

Preceding gene: 38233962

Following gene: 38233960

Centisome position: 56.04

GC content: 49.18

Gene sequence:

>612_bases
GTGATTGTTTCTCTGAGAGGTACAGTCGAATCGATCGGTTTAGGTAGCGCTGTAATCGAATGTAATGGCGTAGGTTATGA
GGTGCTAGCTGCCCCCACAACTCTTGGACGGTTAACTCGGGGAGAGCAGGCGCGGGTGTTAACCACAATGGTGGTCAGGG
AGGAATCCCAAACATTGTATGGGTTTACCGACGATGCTTCACGACGCATGTTTGTTCTGTTGCAGTCGGTATCGGGCTTA
GGTCCTAAACTTGCCTTAGCAGCACAGTCTGTTTTTACTACGGAAGACATCGCTCGACATATCGCTGGGGGTGATGCCAA
GGCTTTGCAGAAGATTCCTGGAGTCGGTAAACGGATGGCTGAACGCATGATCGTTGATCTAAAAGATAAAGTTGTTGGAT
TCAATGACGGTATTCCTGCTGCCGCACAGCCTCAGTTGTCCATTGCCGTCGATCAAGCAGTCCAAGAGCAAGTACTTGAA
GCTCTCGTAGGACTAGGGTTTAGTGAAAAAATTGCATTGCCAGTGTTGTCTCGTGTGTTGCGGGACTCCCCAGAGCTCTC
AAAATCTCAAGCATTGCGCGCAGCATTAAGCGAATTGGGCACTAAGAACTAA

Upstream 100 bases:

>100_bases
CTCTAGCGGTATGCCATTGTTGGCGAGCTCCAATGCTAGCGATACATAACTCCCAGAGATAGCCCGTAACAATAGATATT
TAGAAAAAGGGGTATATGAA

Downstream 100 bases:

>100_bases
ATAGGGGAGAGTTATTCGTGGCTAATATTGAAAAAACCGAGTTTCATGTCCCAGCACCGGTATCTGCTGCTGGGAATCAG
AAAAGCTCACTGGGCAATGC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MIVSLRGTVESIGLGSAVIECNGVGYEVLAAPTTLGRLTRGEQARVLTTMVVREESQTLYGFTDDASRRMFVLLQSVSGL
GPKLALAAQSVFTTEDIARHIAGGDAKALQKIPGVGKRMAERMIVDLKDKVVGFNDGIPAAAQPQLSIAVDQAVQEQVLE
ALVGLGFSEKIALPVLSRVLRDSPELSKSQALRAALSELGTKN

Sequences:

>Translated_203_residues
MIVSLRGTVESIGLGSAVIECNGVGYEVLAAPTTLGRLTRGEQARVLTTMVVREESQTLYGFTDDASRRMFVLLQSVSGL
GPKLALAAQSVFTTEDIARHIAGGDAKALQKIPGVGKRMAERMIVDLKDKVVGFNDGIPAAAQPQLSIAVDQAVQEQVLE
ALVGLGFSEKIALPVLSRVLRDSPELSKSQALRAALSELGTKN
>Mature_203_residues
MIVSLRGTVESIGLGSAVIECNGVGYEVLAAPTTLGRLTRGEQARVLTTMVVREESQTLYGFTDDASRRMFVLLQSVSGL
GPKLALAAQSVFTTEDIARHIAGGDAKALQKIPGVGKRMAERMIVDLKDKVVGFNDGIPAAAQPQLSIAVDQAVQEQVLE
ALVGLGFSEKIALPVLSRVLRDSPELSKSQALRAALSELGTKN

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=205, Percent_Identity=40, Blast_Score=109, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_CORDI (Q6NGX4)

Other databases:

- EMBL:   BX248358
- RefSeq:   NP_939728.1
- ProteinModelPortal:   Q6NGX4
- SMR:   Q6NGX4
- GeneID:   2649907
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1376
- NMPDR:   fig|257309.1.peg.1319
- HOGENOM:   HBG635309
- OMA:   YKTAMSI
- PhylomeDB:   Q6NGX4
- ProtClustDB:   PRK00116
- BioCyc:   CDIP257309:DIP1376-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21486; Mature: 21486

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVSLRGTVESIGLGSAVIECNGVGYEVLAAPTTLGRLTRGEQARVLTTMVVREESQTLY
CEEECCCCHHHCCCCCEEEEECCCCEEEEECCHHHHHHCCCCHHHHHHHHHHHCCCCEEE
GFTDDASRRMFVLLQSVSGLGPKLALAAQSVFTTEDIARHIAGGDAKALQKIPGVGKRMA
EECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHH
ERMIVDLKDKVVGFNDGIPAAAQPQLSIAVDQAVQEQVLEALVGLGFSEKIALPVLSRVL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RDSPELSKSQALRAALSELGTKN
HCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIVSLRGTVESIGLGSAVIECNGVGYEVLAAPTTLGRLTRGEQARVLTTMVVREESQTLY
CEEECCCCHHHCCCCCEEEEECCCCEEEEECCHHHHHHCCCCHHHHHHHHHHHCCCCEEE
GFTDDASRRMFVLLQSVSGLGPKLALAAQSVFTTEDIARHIAGGDAKALQKIPGVGKRMA
EECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHH
ERMIVDLKDKVVGFNDGIPAAAQPQLSIAVDQAVQEQVLEALVGLGFSEKIALPVLSRVL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RDSPELSKSQALRAALSELGTKN
HCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910