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The map label for this gene is sdaB [H]

Identifier: 38233945

GI number: 38233945

Start: 1377106

End: 1378494

Strand: Direct

Name: sdaB [H]

Synonym: DIP1359

Alternate gene names: 38233945

Gene position: 1377106-1378494 (Clockwise)

Preceding gene: 38233944

Following gene: 38233949

Centisome position: 55.34

GC content: 50.83

Gene sequence:

>1389_bases
ATGTCAATCAGTGTCACTGATTTGTTTAGTATCGGAATTGGCCCTTCTTCTTCCCACACCGTTGGGCCACTTCGCGCGGC
TGAAGCATTTCTTAGTGCAAATAACTGCCCTGATGATTCCGAAATTGCTATCACCTTGCATGGTTCCCTTGCCGCCACAG
GTATCGGCCACGGTACAGATCGTGCAGCAATTCTTGGCTTAGCAGGCTACACCCCTATTACCCTTACGCCTGACGTAAAA
CCTGTTTTTGGCTCCGCAATTCCCACCCAAGGAACAGTCAGTGGACCTCGAGGCGAGGTACGTTATCGCCTCATTTTTGA
CCCAGTTCCACTTCCAGAACACCCCAATGCGATGACTTTCGTCGCCTATGGCCCCGATGGCAATCGTATCGGAACCCCTG
CGATCTATTACTCCATCGGTGGTGGTTTCATCGCAACAGCCGATACCATGCGCGAACAAAAAACCCCGGAGTCTGCTGTC
AAATCAGCAAATGAGAACCTAATGCCGTATCCGTTCACCACAGGAGACGAGCTTCTGTATCAATGCCAGAGCAACGCTCT
CAGCATTCCACAGCTAATGGAAGCCAATGAAACAGCAATTCATGGAAGCATCTTGCCTGTGAACGATCATCTCGATTCCG
TATGGGCCACTATGCAAGAATGCGTTAATCAAGGGTTGAGTACGTGGGGAATTCTACCGGGTGGACTCGAAGTAGAACGC
CGTGCGCCACAGCTTTTCCAACATCTCACTGATGGCCCGGTGGACACCGATGATGCCCTTCGCGCAATGGAATGGGTGAA
TCTCTTTGCCCTCGCAGTCAACGAGGAGAACGCAGCCGGTGGGCGGGTTGTCACTGCTCCTACAAATGGTGCGGCAGGAA
TTGTCCCTGCAGTTTTGCAGTACGCTGAAAAATTTGTTCCTCAATTTACGGAAACAAGCCATCGAGATTTCTTGCTAACA
GCTGCCGCTATAGGCATCATCATCAAATACAACGCTTCAATCTCCGGTGCTGAGGTTGGATGCCAAGGTGAAGTCGGCTC
AGCAAGCTCTATGGCCGCTGCTGGTCTATGCCAAGTGCTCAACGGTACCCCACGCCAAGTAGAGCATGCTGCAGAAATAG
CTCTCGAGCACAATCTCGGGCTAACCTGTGATCCAGTCGGCGGCTTGGTCCAAATACCATGCATTGAACGCAACGCAATT
GGTGCAGTGAAATCTATCAATGCAGCTCGCTTATCGCTTATCGGATCAGGTAAACATCGTGTCCGACTCGATGATGCTGT
GCTTACTATGGCTGAAACTGGACGAGACATGCTCACAAAATACAAAGAAACTTCCACAGGCGGTCTAGCTATTCGTCTTG
GGCTTCCTGTCAGCATCACTGAATGCTAA

Upstream 100 bases:

>100_bases
ATATTTTCATTGCAGGTTGCAAAACTGGAGTAGCTAAAGCCACTAAAAATAGCTAGGTTGGTAACTTCACCCATCTTCCC
CACCCCGCTCAAGGAGCAGT

Downstream 100 bases:

>100_bases
AAGCGGTGGGAATGCACGAGTAATAAAAATACTGTGCATTCCCACCGCCGCAAGCGTGGCCTCCTCGTGTCTTACAACGC
TGACTGAATCTCCAAGATCA

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSISVTDLFSIGIGPSSSHTVGPLRAAEAFLSANNCPDDSEIAITLHGSLAATGIGHGTDRAAILGLAGYTPITLTPDVK
PVFGSAIPTQGTVSGPRGEVRYRLIFDPVPLPEHPNAMTFVAYGPDGNRIGTPAIYYSIGGGFIATADTMREQKTPESAV
KSANENLMPYPFTTGDELLYQCQSNALSIPQLMEANETAIHGSILPVNDHLDSVWATMQECVNQGLSTWGILPGGLEVER
RAPQLFQHLTDGPVDTDDALRAMEWVNLFALAVNEENAAGGRVVTAPTNGAAGIVPAVLQYAEKFVPQFTETSHRDFLLT
AAAIGIIIKYNASISGAEVGCQGEVGSASSMAAAGLCQVLNGTPRQVEHAAEIALEHNLGLTCDPVGGLVQIPCIERNAI
GAVKSINAARLSLIGSGKHRVRLDDAVLTMAETGRDMLTKYKETSTGGLAIRLGLPVSITEC

Sequences:

>Translated_462_residues
MSISVTDLFSIGIGPSSSHTVGPLRAAEAFLSANNCPDDSEIAITLHGSLAATGIGHGTDRAAILGLAGYTPITLTPDVK
PVFGSAIPTQGTVSGPRGEVRYRLIFDPVPLPEHPNAMTFVAYGPDGNRIGTPAIYYSIGGGFIATADTMREQKTPESAV
KSANENLMPYPFTTGDELLYQCQSNALSIPQLMEANETAIHGSILPVNDHLDSVWATMQECVNQGLSTWGILPGGLEVER
RAPQLFQHLTDGPVDTDDALRAMEWVNLFALAVNEENAAGGRVVTAPTNGAAGIVPAVLQYAEKFVPQFTETSHRDFLLT
AAAIGIIIKYNASISGAEVGCQGEVGSASSMAAAGLCQVLNGTPRQVEHAAEIALEHNLGLTCDPVGGLVQIPCIERNAI
GAVKSINAARLSLIGSGKHRVRLDDAVLTMAETGRDMLTKYKETSTGGLAIRLGLPVSITEC
>Mature_461_residues
SISVTDLFSIGIGPSSSHTVGPLRAAEAFLSANNCPDDSEIAITLHGSLAATGIGHGTDRAAILGLAGYTPITLTPDVKP
VFGSAIPTQGTVSGPRGEVRYRLIFDPVPLPEHPNAMTFVAYGPDGNRIGTPAIYYSIGGGFIATADTMREQKTPESAVK
SANENLMPYPFTTGDELLYQCQSNALSIPQLMEANETAIHGSILPVNDHLDSVWATMQECVNQGLSTWGILPGGLEVERR
APQLFQHLTDGPVDTDDALRAMEWVNLFALAVNEENAAGGRVVTAPTNGAAGIVPAVLQYAEKFVPQFTETSHRDFLLTA
AAIGIIIKYNASISGAEVGCQGEVGSASSMAAAGLCQVLNGTPRQVEHAAEIALEHNLGLTCDPVGGLVQIPCIERNAIG
AVKSINAARLSLIGSGKHRVRLDDAVLTMAETGRDMLTKYKETSTGGLAIRLGLPVSITEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=461, Percent_Identity=48.8069414316703, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1788116, Length=461, Percent_Identity=48.590021691974, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI48994925, Length=461, Percent_Identity=48.1561822125813, Blast_Score=396, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48483; Mature: 48351

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISVTDLFSIGIGPSSSHTVGPLRAAEAFLSANNCPDDSEIAITLHGSLAATGIGHGTD
CCEEHEEHEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCEEECCCCCCCC
RAAILGLAGYTPITLTPDVKPVFGSAIPTQGTVSGPRGEVRYRLIFDPVPLPEHPNAMTF
CEEEEEECCCCCEEECCCCCHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEE
VAYGPDGNRIGTPAIYYSIGGGFIATADTMREQKTPESAVKSANENLMPYPFTTGDELLY
EEECCCCCCCCCCEEEEEECCCEEEEHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHH
QCQSNALSIPQLMEANETAIHGSILPVNDHLDSVWATMQECVNQGLSTWGILPGGLEVER
HHHCCCCCCHHHHCCCCCEECCEEEECCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHH
RAPQLFQHLTDGPVDTDDALRAMEWVNLFALAVNEENAAGGRVVTAPTNGAAGIVPAVLQ
HHHHHHHHHCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHH
YAEKFVPQFTETSHRDFLLTAAAIGIIIKYNASISGAEVGCQGEVGSASSMAAAGLCQVL
HHHHHCCHHCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
NGTPRQVEHAAEIALEHNLGLTCDPVGGLVQIPCIERNAIGAVKSINAARLSLIGSGKHR
CCCHHHHHHHHHHHEECCCCEEECCCCCEEEECEECCCCCCHHHCCCCEEEEEEECCCCE
VRLDDAVLTMAETGRDMLTKYKETSTGGLAIRLGLPVSITEC
EEEHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCEEEECC
>Mature Secondary Structure 
SISVTDLFSIGIGPSSSHTVGPLRAAEAFLSANNCPDDSEIAITLHGSLAATGIGHGTD
CEEHEEHEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCEEECCCCCCCC
RAAILGLAGYTPITLTPDVKPVFGSAIPTQGTVSGPRGEVRYRLIFDPVPLPEHPNAMTF
CEEEEEECCCCCEEECCCCCHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEE
VAYGPDGNRIGTPAIYYSIGGGFIATADTMREQKTPESAVKSANENLMPYPFTTGDELLY
EEECCCCCCCCCCEEEEEECCCEEEEHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHH
QCQSNALSIPQLMEANETAIHGSILPVNDHLDSVWATMQECVNQGLSTWGILPGGLEVER
HHHCCCCCCHHHHCCCCCEECCEEEECCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHH
RAPQLFQHLTDGPVDTDDALRAMEWVNLFALAVNEENAAGGRVVTAPTNGAAGIVPAVLQ
HHHHHHHHHCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHH
YAEKFVPQFTETSHRDFLLTAAAIGIIIKYNASISGAEVGCQGEVGSASSMAAAGLCQVL
HHHHHCCHHCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
NGTPRQVEHAAEIALEHNLGLTCDPVGGLVQIPCIERNAIGAVKSINAARLSLIGSGKHR
CCCHHHHHHHHHHHEECCCCEEECCCCCEEEECEECCCCCCHHHCCCCEEEEEEECCCCE
VRLDDAVLTMAETGRDMLTKYKETSTGGLAIRLGLPVSITEC
EEEHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]