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The map label for this gene is aroB

Identifier: 38233929

GI number: 38233929

Start: 1355712

End: 1356791

Strand: Reverse

Name: aroB

Synonym: DIP1343

Alternate gene names: 38233929

Gene position: 1356791-1355712 (Counterclockwise)

Preceding gene: 38233930

Following gene: 38233928

Centisome position: 54.52

GC content: 45.65

Gene sequence:

>1080_bases
GTGCCAACTATAGAAGTGAAAAGCAGTAATCCGTACCAAGTACGGATTGATAAACAACTAAACACTGAGATCGTTACAAC
AGCACAACTCAGCGGTGCGGAAAACGTAGCGATCATCACACAACCTCCACTTCTTGAACGTGCTGGAACGCTTGAAAAGA
TGCTGGCACAAGCGGGACTTGCTTCTCATGTTTTGGCTGTGCCTGATGCTGAAACTGGTAAAACTCTTGAAGTCGCTGGA
CGTTGTTGGGATCAGCTAGGCGAATGGGGCTTTTCTCGAAGCGATCTAATAATCGGATTCGGTGGTGGGGCTGCAACAGA
TTTGGCTGGATTTGTTGCAGCAGCTTGGATGCGCGGCATAAAAGTAATTCAGGTACCTACTACGTTATTAGCAATGGTTG
ATGCAGCAGTCGGGGGGAAGACTGGTATCAATACTGCGGCTGGAAAAAACTTAGTGGGAGCATTCCACGAGCCGATTGCG
GTGTTTATCGATGTGGATCATCTCGATTCATTGCCACAGGATGAGATTATTGCGGGGTCGGCTGAAATCATAAAAACTGG
TTTTATTGCAGATCCTAGAATTCTCGAATTATATGAGAAAGATCCGGCAGCTTGTTTGCTTAAAGATGGGCACCTTCCGG
AACTTATTGCGCGCTCAATTGCCGTGAAATCAAAAGTTGTAAGTCAAGATTTAAAGGAATCAGGTTTACGCGAGATCCTA
AACTATGGGCACACTTTTGGGCATGCAGTTGAACTGCGTGAAAATTTTTCTTGGCGGCATGGAAATGCTGTAGCCGTGGG
AATGGTATTTGTCGCGGAGTTGGCCAACATTCGTGGTCTTATCTCTGACGAGCTGGTAGAACGGCATCGCAAAATTTTAA
AGTCGATAGGGTTGCCTACCTCATATTCGCAAGGCCACTTTGAAGAACTTCATCAAGGCATGAAGCATGATAAGAAGAAT
CGAAATAGCATGATTCGATTCGTCGCTTTACGTGACATAAGTGATGTCGTTCGCCTTGAAGGTCCTACTGACGAAGAACT
TTTCCAAGCATATTCGCGCCTTGCATTGGAGATGAGCTAA

Upstream 100 bases:

>100_bases
AGTCCACAGCAAATTGTTGCTGATATTTTGGGCTTTCTTGAAACCTTACGTTGAATCGTGTGACTAGTTTTATCGCCGTA
TGCCGAAAAGGAATTAAATA

Downstream 100 bases:

>100_bases
ATGAATGTTGTGATCCTCAACGGTCCAAACTTAGATCGGTTAGGCAAACGTCAGCCTGAAATTTATGGTTCGACAACTCT
GGCAGACGTAGAACTTGAGT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MPTIEVKSSNPYQVRIDKQLNTEIVTTAQLSGAENVAIITQPPLLERAGTLEKMLAQAGLASHVLAVPDAETGKTLEVAG
RCWDQLGEWGFSRSDLIIGFGGGAATDLAGFVAAAWMRGIKVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGAFHEPIA
VFIDVDHLDSLPQDEIIAGSAEIIKTGFIADPRILELYEKDPAACLLKDGHLPELIARSIAVKSKVVSQDLKESGLREIL
NYGHTFGHAVELRENFSWRHGNAVAVGMVFVAELANIRGLISDELVERHRKILKSIGLPTSYSQGHFEELHQGMKHDKKN
RNSMIRFVALRDISDVVRLEGPTDEELFQAYSRLALEMS

Sequences:

>Translated_359_residues
MPTIEVKSSNPYQVRIDKQLNTEIVTTAQLSGAENVAIITQPPLLERAGTLEKMLAQAGLASHVLAVPDAETGKTLEVAG
RCWDQLGEWGFSRSDLIIGFGGGAATDLAGFVAAAWMRGIKVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGAFHEPIA
VFIDVDHLDSLPQDEIIAGSAEIIKTGFIADPRILELYEKDPAACLLKDGHLPELIARSIAVKSKVVSQDLKESGLREIL
NYGHTFGHAVELRENFSWRHGNAVAVGMVFVAELANIRGLISDELVERHRKILKSIGLPTSYSQGHFEELHQGMKHDKKN
RNSMIRFVALRDISDVVRLEGPTDEELFQAYSRLALEMS
>Mature_358_residues
PTIEVKSSNPYQVRIDKQLNTEIVTTAQLSGAENVAIITQPPLLERAGTLEKMLAQAGLASHVLAVPDAETGKTLEVAGR
CWDQLGEWGFSRSDLIIGFGGGAATDLAGFVAAAWMRGIKVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGAFHEPIAV
FIDVDHLDSLPQDEIIAGSAEIIKTGFIADPRILELYEKDPAACLLKDGHLPELIARSIAVKSKVVSQDLKESGLREILN
YGHTFGHAVELRENFSWRHGNAVAVGMVFVAELANIRGLISDELVERHRKILKSIGLPTSYSQGHFEELHQGMKHDKKNR
NSMIRFVALRDISDVVRLEGPTDEELFQAYSRLALEMS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=296, Percent_Identity=38.5135135135135, Blast_Score=180, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6320332, Length=309, Percent_Identity=37.5404530744337, Blast_Score=181, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_CORDI (Q6NH04)

Other databases:

- EMBL:   BX248357
- RefSeq:   NP_939696.1
- ProteinModelPortal:   Q6NH04
- SMR:   Q6NH04
- GeneID:   2648786
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1343
- NMPDR:   fig|257309.1.peg.1287
- HOGENOM:   HBG632303
- OMA:   EKDFRET
- ProtClustDB:   PRK00002
- BioCyc:   CDIP257309:DIP1343-MONOMER
- BRENDA:   4.2.3.4
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39005; Mature: 38874

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTIEVKSSNPYQVRIDKQLNTEIVTTAQLSGAENVAIITQPPLLERAGTLEKMLAQAGL
CCCEEECCCCCEEEEECCCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCH
ASHVLAVPDAETGKTLEVAGRCWDQLGEWGFSRSDLIIGFGGGAATDLAGFVAAAWMRGI
HHCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCC
KVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGAFHEPIAVFIDVDHLDSLPQDEIIAGS
EEEEHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHCCCEEEEEEHHHHCCCCCCCEECCC
AEIIKTGFIADPRILELYEKDPAACLLKDGHLPELIARSIAVKSKVVSQDLKESGLREIL
HHHHHHCCCCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NYGHTFGHAVELRENFSWRHGNAVAVGMVFVAELANIRGLISDELVERHRKILKSIGLPT
HCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SYSQGHFEELHQGMKHDKKNRNSMIRFVALRDISDVVRLEGPTDEELFQAYSRLALEMS
CCCCCHHHHHHHHHHHHHCCHHHHEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PTIEVKSSNPYQVRIDKQLNTEIVTTAQLSGAENVAIITQPPLLERAGTLEKMLAQAGL
CCEEECCCCCEEEEECCCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCH
ASHVLAVPDAETGKTLEVAGRCWDQLGEWGFSRSDLIIGFGGGAATDLAGFVAAAWMRGI
HHCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCC
KVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGAFHEPIAVFIDVDHLDSLPQDEIIAGS
EEEEHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHCCCEEEEEEHHHHCCCCCCCEECCC
AEIIKTGFIADPRILELYEKDPAACLLKDGHLPELIARSIAVKSKVVSQDLKESGLREIL
HHHHHHCCCCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NYGHTFGHAVELRENFSWRHGNAVAVGMVFVAELANIRGLISDELVERHRKILKSIGLPT
HCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SYSQGHFEELHQGMKHDKKNRNSMIRFVALRDISDVVRLEGPTDEELFQAYSRLALEMS
CCCCCHHHHHHHHHHHHHCCHHHHEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910