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The map label for this gene is aroQ

Identifier: 38233928

GI number: 38233928

Start: 1355271

End: 1355711

Strand: Reverse

Name: aroQ

Synonym: DIP1342

Alternate gene names: 38233928

Gene position: 1355711-1355271 (Counterclockwise)

Preceding gene: 38233929

Following gene: 38233927

Centisome position: 54.48

GC content: 45.35

Gene sequence:

>441_bases
ATGAATGTTGTGATCCTCAACGGTCCAAACTTAGATCGGTTAGGCAAACGTCAGCCTGAAATTTATGGTTCGACAACTCT
GGCAGACGTAGAACTTGAGTTGTTTCGACTCGCTGGGCAATTAGGCGTTGACGTCGAATGTAAACAGTCAAACTATGAAG
GTGAATTGATCGACTGGATACACTGTGCGGCGGATGCAGGTAATCCCGTGATCATTAACCCCGGAGGGCTAACCCATACT
TCGGTGGCATTGCGTGATGCATTGGCTGAAATATCAGATGGTCCAGGGTTCATTGAAGTCCATATTTCGAATATTCATGC
GCGAGAAGAATTTAGACACCACAGTTATTTGTCTCCAATCGCGACTGGAGTTATCGCCGGACTGGGAACAATCGGTTACG
AATTAGCTCTCCGATATGTAGTTTCGACTTTAAACTCATAA

Upstream 100 bases:

>100_bases
CGTCGCTTTACGTGACATAAGTGATGTCGTTCGCCTTGAAGGTCCTACTGACGAAGAACTTTTCCAAGCATATTCGCGCC
TTGCATTGGAGATGAGCTAA

Downstream 100 bases:

>100_bases
AAAACTCTCATCGATGTAGGAGAATATGACTATGCCATTGGCTGATACTCGTTTTTTACAGCGCCGACGTGCTCTTTCTG
CACAGCTTGCAGCCAAGCGT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MNVVILNGPNLDRLGKRQPEIYGSTTLADVELELFRLAGQLGVDVECKQSNYEGELIDWIHCAADAGNPVIINPGGLTHT
SVALRDALAEISDGPGFIEVHISNIHAREEFRHHSYLSPIATGVIAGLGTIGYELALRYVVSTLNS

Sequences:

>Translated_146_residues
MNVVILNGPNLDRLGKRQPEIYGSTTLADVELELFRLAGQLGVDVECKQSNYEGELIDWIHCAADAGNPVIINPGGLTHT
SVALRDALAEISDGPGFIEVHISNIHAREEFRHHSYLSPIATGVIAGLGTIGYELALRYVVSTLNS
>Mature_146_residues
MNVVILNGPNLDRLGKRQPEIYGSTTLADVELELFRLAGQLGVDVECKQSNYEGELIDWIHCAADAGNPVIINPGGLTHT
SVALRDALAEISDGPGFIEVHISNIHAREEFRHHSYLSPIATGVIAGLGTIGYELALRYVVSTLNS

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_CORDI (Q6NH05)

Other databases:

- EMBL:   BX248357
- RefSeq:   NP_939695.1
- ProteinModelPortal:   Q6NH05
- SMR:   Q6NH05
- GeneID:   2648785
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1342
- NMPDR:   fig|257309.1.peg.1286
- HOGENOM:   HBG284657
- OMA:   GWLHEAA
- ProtClustDB:   PRK05395
- BioCyc:   CDIP257309:DIP1342-MONOMER
- BRENDA:   4.2.1.10
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15763; Mature: 15763

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 101-101 BINDING 73-73 BINDING 79-79 BINDING 86-86 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVVILNGPNLDRLGKRQPEIYGSTTLADVELELFRLAGQLGVDVECKQSNYEGELIDWI
CEEEEECCCCHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHH
HCAADAGNPVIINPGGLTHTSVALRDALAEISDGPGFIEVHISNIHAREEFRHHSYLSPI
HHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
ATGVIAGLGTIGYELALRYVVSTLNS
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVVILNGPNLDRLGKRQPEIYGSTTLADVELELFRLAGQLGVDVECKQSNYEGELIDWI
CEEEEECCCCHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHH
HCAADAGNPVIINPGGLTHTSVALRDALAEISDGPGFIEVHISNIHAREEFRHHSYLSPI
HHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
ATGVIAGLGTIGYELALRYVVSTLNS
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910