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The map label for this gene is pyrR

Identifier: 38233921

GI number: 38233921

Start: 1349761

End: 1350333

Strand: Reverse

Name: pyrR

Synonym: DIP1335

Alternate gene names: 38233921

Gene position: 1350333-1349761 (Counterclockwise)

Preceding gene: 38233925

Following gene: 38233920

Centisome position: 54.26

GC content: 46.77

Gene sequence:

>573_bases
ATGAGTGAAAACAATGGCGACAATATCGAACTTCTTTCGGAAAACGATGTTGCTCGTACTATTGCACGCATCGCGCACCA
AATTATTGAAAAAACTGCGCTCGACGCACCAGGTACAAAGCCCGTTTTGCTGCTCGGTATTCCTTCTGGTGGAGTGCCTA
TCGCGTCTCAAATTGCGCAGAAAATCAAAGAATTTACCGGAGTTGATGTCCCGGTTGGTTCACTAGATGTAACCCTGTAC
CGTGACGATCTGAGAAAAAATCCCCATCGTGCGTTACAGCCAACTAACCTCCCGCTAGATGGAATAAATGGGCATCATAT
TATTTTGGTAGATGATGTTCTTTATTCTGGCCGCACAATTCGTGCCGCTCTTGATGCACTTCGCGATATCGGTCGACCAG
ATATTATTCAGCTCGCTGTATTGGTGGATAGGGGCCACCGACAGTTGCCTATCCGCGCAGATTATGTTGGCAAGAATTTG
CCTACTTCTCGTGGCGAAGATGTTCAAGTGTTTATCAAAGAAATTGATGGCCGAACAGCCGTTGTCTTAACTCGTGGCAC
GGAGGAAGCATAG

Upstream 100 bases:

>100_bases
TAGTTCGTCTTAGTGCTTACTTAGGTGCAGAGTACTCTGCAAATATCATGAATCGGCATCCTTTAACAGACCGCACAGAG
AGGCGGGAAAGGAGGTCACG

Downstream 100 bases:

>100_bases
TGAAACATCTATTATCTATTGCTGACCTTAGCAAAGATGACATCATTGGTTTGATGGATGAAGCGGATCGTTTCCGAGAA
GCACTCTTAGGGCGTGATAT

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MSENNGDNIELLSENDVARTIARIAHQIIEKTALDAPGTKPVLLLGIPSGGVPIASQIAQKIKEFTGVDVPVGSLDVTLY
RDDLRKNPHRALQPTNLPLDGINGHHIILVDDVLYSGRTIRAALDALRDIGRPDIIQLAVLVDRGHRQLPIRADYVGKNL
PTSRGEDVQVFIKEIDGRTAVVLTRGTEEA

Sequences:

>Translated_190_residues
MSENNGDNIELLSENDVARTIARIAHQIIEKTALDAPGTKPVLLLGIPSGGVPIASQIAQKIKEFTGVDVPVGSLDVTLY
RDDLRKNPHRALQPTNLPLDGINGHHIILVDDVLYSGRTIRAALDALRDIGRPDIIQLAVLVDRGHRQLPIRADYVGKNL
PTSRGEDVQVFIKEIDGRTAVVLTRGTEEA
>Mature_189_residues
SENNGDNIELLSENDVARTIARIAHQIIEKTALDAPGTKPVLLLGIPSGGVPIASQIAQKIKEFTGVDVPVGSLDVTLYR
DDLRKNPHRALQPTNLPLDGINGHHIILVDDVLYSGRTIRAALDALRDIGRPDIIQLAVLVDRGHRQLPIRADYVGKNLP
TSRGEDVQVFIKEIDGRTAVVLTRGTEEA

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_CORDI (Q6NH12)

Other databases:

- EMBL:   BX248357
- RefSeq:   NP_939688.1
- HSSP:   P65941
- ProteinModelPortal:   Q6NH12
- SMR:   Q6NH12
- GeneID:   2648778
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1335
- NMPDR:   fig|257309.1.peg.1279
- HOGENOM:   HBG641958
- OMA:   ILDITLY
- ProtClustDB:   PRK05205
- BioCyc:   CDIP257309:DIP1335-MONOMER
- BRENDA:   2.4.2.9
- GO:   GO:0006350
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 20669; Mature: 20538

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENNGDNIELLSENDVARTIARIAHQIIEKTALDAPGTKPVLLLGIPSGGVPIASQIAQ
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHH
KIKEFTGVDVPVGSLDVTLYRDDLRKNPHRALQPTNLPLDGINGHHIILVDDVLYSGRTI
HHHHHCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHCCCHH
RAALDALRDIGRPDIIQLAVLVDRGHRQLPIRADYVGKNLPTSRGEDVQVFIKEIDGRTA
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEHHHCCCCCCCCCCCCCEEEEECCCCCEE
VVLTRGTEEA
EEEECCCCCC
>Mature Secondary Structure 
SENNGDNIELLSENDVARTIARIAHQIIEKTALDAPGTKPVLLLGIPSGGVPIASQIAQ
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHH
KIKEFTGVDVPVGSLDVTLYRDDLRKNPHRALQPTNLPLDGINGHHIILVDDVLYSGRTI
HHHHHCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHCCCHH
RAALDALRDIGRPDIIQLAVLVDRGHRQLPIRADYVGKNLPTSRGEDVQVFIKEIDGRTA
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEHHHCCCCCCCCCCCCCEEEEECCCCCEE
VVLTRGTEEA
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910