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The map label for this gene is cobK [H]

Identifier: 38233822

GI number: 38233822

Start: 1236065

End: 1236796

Strand: Reverse

Name: cobK [H]

Synonym: DIP1234

Alternate gene names: 38233822

Gene position: 1236796-1236065 (Counterclockwise)

Preceding gene: 38233823

Following gene: 38233817

Centisome position: 49.7

GC content: 51.64

Gene sequence:

>732_bases
ATGCGCGCACTAATCTTGGGAGGTACTGGGGAAGGTCGCGACGTAGCTGCAATTCTTCACGTTGCAGGTTGGCGCGTGAC
AAGTTCCTTAGCCGGGCGTGTTTCCAATCCGAAGCTTCCAGTCGGCGAGGTCAGAATCGGAGGTTTTGGAGGGCCTGCCG
GGCTAACACAGTGGCTTTTGCGCGAAGGGGTTGAAGTCATCATTGATGCAACCCATCCTTTTGCAGAACGTATTAGTGCT
TCAGCCGCCGAAGCAAGCAGAGCTACTGGTATTCCTTTGATTGCATTACATCGCCCCGAATGGAAGCCAAGGCCCCGTGA
CCGGTGGATTCCAGTGACGTCAATGCAGGAAGCCGCAGATAAAGCTGCGCGTGACTATCACCATATTTTTCTAACAATTG
GCCGACAGCAACTAGCCCCATTTGCTCACGACGCTCATAACCTTTACGTCGTACGTGCCGTAGAGCCTCCCCAAGTGGCG
TTGCCTCAACGTCATCGGCTCATACTTTCTCGTGGTCCTTTCACACTGGAAAGCGAGAAGAAATTGATGATTGATAACCA
GATAGACTGTGTTGTTACCAAAAATTCTGGTGGGCCGCTCACACACGCCAAACTTGATGCCGCCCGCGACCTAGGTATTG
ACGTAGTAATGGTGCAACGACCTCAATTACCCAAGGTTACTCATGTTGCCACCTCGGCTGCAGAGGTAGCTGAAATTATT
GATTCCTTGTAA

Upstream 100 bases:

>100_bases
CAATTATTGTGGTCGGAAAAGTGCTCGGAGCTGAAGGTTTCCCCGATTCATTCCTATACTCCAATGACCGACCTCGAGAT
GAGCATGGTAGGACGATTCC

Downstream 100 bases:

>100_bases
CTCCGGATGTAAATAATCGGTGTGGCCTCGAGCTTTTCTCATCTAAAAGCTCGATGCCACACCGATTTAATTGCTCAAAA
ACTAGGTGTACCACCGCGAG

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRALILGGTGEGRDVAAILHVAGWRVTSSLAGRVSNPKLPVGEVRIGGFGGPAGLTQWLLREGVEVIIDATHPFAERISA
SAAEASRATGIPLIALHRPEWKPRPRDRWIPVTSMQEAADKAARDYHHIFLTIGRQQLAPFAHDAHNLYVVRAVEPPQVA
LPQRHRLILSRGPFTLESEKKLMIDNQIDCVVTKNSGGPLTHAKLDAARDLGIDVVMVQRPQLPKVTHVATSAAEVAEII
DSL

Sequences:

>Translated_243_residues
MRALILGGTGEGRDVAAILHVAGWRVTSSLAGRVSNPKLPVGEVRIGGFGGPAGLTQWLLREGVEVIIDATHPFAERISA
SAAEASRATGIPLIALHRPEWKPRPRDRWIPVTSMQEAADKAARDYHHIFLTIGRQQLAPFAHDAHNLYVVRAVEPPQVA
LPQRHRLILSRGPFTLESEKKLMIDNQIDCVVTKNSGGPLTHAKLDAARDLGIDVVMVQRPQLPKVTHVATSAAEVAEII
DSL
>Mature_243_residues
MRALILGGTGEGRDVAAILHVAGWRVTSSLAGRVSNPKLPVGEVRIGGFGGPAGLTQWLLREGVEVIIDATHPFAERISA
SAAEASRATGIPLIALHRPEWKPRPRDRWIPVTSMQEAADKAARDYHHIFLTIGRQQLAPFAHDAHNLYVVRAVEPPQVA
LPQRHRLILSRGPFTLESEKKLMIDNQIDCVVTKNSGGPLTHAKLDAARDLGIDVVMVQRPQLPKVTHVATSAAEVAEII
DSL

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 26377; Mature: 26377

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALILGGTGEGRDVAAILHVAGWRVTSSLAGRVSNPKLPVGEVRIGGFGGPAGLTQWLL
CEEEEECCCCCCCHHEEEEHHHCHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHH
REGVEVIIDATHPFAERISASAAEASRATGIPLIALHRPEWKPRPRDRWIPVTSMQEAAD
HCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEECCCCHHHHHH
KAARDYHHIFLTIGRQQLAPFAHDAHNLYVVRAVEPPQVALPQRHRLILSRGPFTLESEK
HHHHHHEEEEEEECHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCEEECCCC
KLMIDNQIDCVVTKNSGGPLTHAKLDAARDLGIDVVMVQRPQLPKVTHVATSAAEVAEII
EEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
DSL
HCC
>Mature Secondary Structure
MRALILGGTGEGRDVAAILHVAGWRVTSSLAGRVSNPKLPVGEVRIGGFGGPAGLTQWLL
CEEEEECCCCCCCHHEEEEHHHCHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHH
REGVEVIIDATHPFAERISASAAEASRATGIPLIALHRPEWKPRPRDRWIPVTSMQEAAD
HCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEECCCCHHHHHH
KAARDYHHIFLTIGRQQLAPFAHDAHNLYVVRAVEPPQVALPQRHRLILSRGPFTLESEK
HHHHHHEEEEEEECHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCEEECCCC
KLMIDNQIDCVVTKNSGGPLTHAKLDAARDLGIDVVMVQRPQLPKVTHVATSAAEVAEII
EEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
DSL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200543 [H]