| Definition | Corynebacterium diphtheriae NCTC 13129 chromosome, complete genome. |
|---|---|
| Accession | NC_002935 |
| Length | 2,488,635 |
Click here to switch to the map view.
The map label for this gene is ptsG [H]
Identifier: 38233741
GI number: 38233741
Start: 1137670
End: 1139700
Strand: Reverse
Name: ptsG [H]
Synonym: DIP1151
Alternate gene names: 38233741
Gene position: 1139700-1137670 (Counterclockwise)
Preceding gene: 38233746
Following gene: 38233740
Centisome position: 45.8
GC content: 54.31
Gene sequence:
>2031_bases ATGTCTACGCAAACACGCGAAGATACCGCTCGGGCCATCCTTGATGGCATCGGTGGCGCGAGCAACATTACGTCGTTTAC GCACTGTGCAACTCGCCTGCGTTTCGAGCTTGCCGACGCCTCCAAGGTTGATAAAGCAGCCCTCGACTCCATACCTAAGG TCATGGGTGCGGTCCCACAAGGTGGCCGTAATTATCAGGTCGTTATTGGTGGCGACGTAGCCAACGTCTATGACGACATG ACCCACCTTCCCGAGATGAAGTCTGCGGCTCCTTCAGATGCTGATATCAAGGCTGCGGCTCGCGCAAAGTCTAAGGGCAA ACTGCCATGGATGGACTCCTTCTTTGAGTACCTATCCGACTCCTTCCGCCCAATTTTGGGCGTGCTGCTGGGCGCCTCCC TCATTATCGCGTTCACGGCTGTGCTCGACGCATTCCACATCGTCGACTTCCGCGCAGACGACAAGTCGGCTTCTTGGGTC TTCGTCGATGCAATGTGGCGCTCAGTCTTCTACTTCCTGCCAGTCATGGTGGCCTTCAACGCGGGTAAGAAACTGCGTAT CGATCCGTGGGTTCCAGCCGCCATTATGTTTGCGCTATTTACCCCAGAGTTCCTTGGTCTTAAAGAGAGCTCTACTGCGG AATGCGTGACCAACGCAGCCCTGGGCACTGAAACCTGCCACGCTCCAATCTTCGGCATCAACATGACTTTCCCCGATTAC GGCGGAAACGTCTTCGTGCCATTGATCATGGCCGCTGTCGCTGCCGTTGTTTACAAGGGCTTCCAGAAAGTTATCCCTAC CGCAGTTCACATGGTTTTCGTACCATTCCTGACTTTGGTCATTATGATTCCTGTGACCGCCTTCATCATCGGCCCATTCG GCACCTGGGCTGGTAACGGTATCGGTCTTGGCTTGTCCTGGATGAACGAGAACGCACCATTCGTCTTCGCTCTTGCTATT CCACTGCTATACCCATTCTTGGTTCCACTCGGTCTGCACTGGCCTCTGAACGCCTTGATGCTTATCAACATTCAGACCTT GGGCTACGACTTCATTCAAGGCCCTATGGGTACTTGGAACTTCGCTTGCTTCGGTGCTACCGCCGGCGTCTTGGCACTGT CCATCCGCGACAAGGACACCGTAATGCGACAGACCGCTGGTTCTGCTCTAGCTGCAGGTCTTCTCGGCGGCATCTCCGAG CCTTCCCTCTACGGTATTCACCTCCGCTTCAAACGCGTGTACCCACGTATGCTCGCCGGATGTTTTGCAGGCGGCTTGAC CATCGCTGTATTGTCCACCATCTTCGAACCAGTAACCACTAACGCCTTCGTCTTTACTTCGATCCCAACTATGTTCGTGT TTAACCCAGCATGGATCTACATGGTTTCGATCTTGGTCGCCTTCACCGTGGCATTCCTCGCCATCTTCATCACCGACTAC CGCACTACAGAAGAAAAAGCAGAATTCTTTGCTCGTCGCGACAGTGCTGACGATGTTCCTGCCGCAACAGTCCCATCAGC TACTACCCCAGCGCCTGCAGCTGCAGCTGCTAATCCTGCTGGCGAGTGCAAAGTCGGCTCCCCTATTTCCGGCGAAGTAC TCCCTATGGCAGAAATCGCCGATCCTGTATTTTCCGCAGGCACACTAGGCGACGGCGTCGGAGTTAACCCAACGGCGACT GCTGGTGCCGGCACAGAGGTTTATTCACCAGTCTCCGGCACCGTTAAATCTGCCATGAAGTCCGGCCATGCTTACGGAAT TAAGACAGATGACGGCGTCGAGGTTCTCGTTCACATCGGAATTGATACCGTTCAAATGAAGGGCGAAGGTTTCACTCCTG CAGTCCAAAAGGGCGACCGTGTTGAAGCAGGACAAAAACTCGCAACTGTTGATTATGACAAGGTTCGCGCTGCAGGATAT GGCACCACCATCGTCGTTGCAGTTACCAACACAAAGGCAATGAAGGCCGTAACCCCAACCGGCGTCAAGCATGCCGGCGC GGGTGACACCATCTTCACTGTTACGCAATAA
Upstream 100 bases:
>100_bases CGGGCAAGACCTAGGACGCTTAATTGCAGCGCCCTAGGTCTTTTGTGGTTTCTAAGCTTTTAAAGAGATCGAGCCCATCC ATAAATGAAAGGAAAAGCGA
Downstream 100 bases:
>100_bases ACTGAACATTCGATACGGCCCCCTGTTATAGGGCAGCCTTCGAAGTCACTGCGAGCCAAGAGCAGGGTCGTTTCCTTTCA AGGAAGCGGCCCTGCTTTAG
Product: PTS system, glucose-specific IIABC component
Products: NA
Alternate protein names: EII-Man/EIII-Man; EIIBCA-Man; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component; Mannose permease IIC component; PTS system mannose-specific EIIC component; Mannose-specific phosphotransferase enzyme IIA component; PTS system mannose-specific EIIA component [H]
Number of amino acids: Translated: 676; Mature: 675
Protein sequence:
>676_residues MSTQTREDTARAILDGIGGASNITSFTHCATRLRFELADASKVDKAALDSIPKVMGAVPQGGRNYQVVIGGDVANVYDDM THLPEMKSAAPSDADIKAAARAKSKGKLPWMDSFFEYLSDSFRPILGVLLGASLIIAFTAVLDAFHIVDFRADDKSASWV FVDAMWRSVFYFLPVMVAFNAGKKLRIDPWVPAAIMFALFTPEFLGLKESSTAECVTNAALGTETCHAPIFGINMTFPDY GGNVFVPLIMAAVAAVVYKGFQKVIPTAVHMVFVPFLTLVIMIPVTAFIIGPFGTWAGNGIGLGLSWMNENAPFVFALAI PLLYPFLVPLGLHWPLNALMLINIQTLGYDFIQGPMGTWNFACFGATAGVLALSIRDKDTVMRQTAGSALAAGLLGGISE PSLYGIHLRFKRVYPRMLAGCFAGGLTIAVLSTIFEPVTTNAFVFTSIPTMFVFNPAWIYMVSILVAFTVAFLAIFITDY RTTEEKAEFFARRDSADDVPAATVPSATTPAPAAAAANPAGECKVGSPISGEVLPMAEIADPVFSAGTLGDGVGVNPTAT AGAGTEVYSPVSGTVKSAMKSGHAYGIKTDDGVEVLVHIGIDTVQMKGEGFTPAVQKGDRVEAGQKLATVDYDKVRAAGY GTTIVVAVTNTKAMKAVTPTGVKHAGAGDTIFTVTQ
Sequences:
>Translated_676_residues MSTQTREDTARAILDGIGGASNITSFTHCATRLRFELADASKVDKAALDSIPKVMGAVPQGGRNYQVVIGGDVANVYDDM THLPEMKSAAPSDADIKAAARAKSKGKLPWMDSFFEYLSDSFRPILGVLLGASLIIAFTAVLDAFHIVDFRADDKSASWV FVDAMWRSVFYFLPVMVAFNAGKKLRIDPWVPAAIMFALFTPEFLGLKESSTAECVTNAALGTETCHAPIFGINMTFPDY GGNVFVPLIMAAVAAVVYKGFQKVIPTAVHMVFVPFLTLVIMIPVTAFIIGPFGTWAGNGIGLGLSWMNENAPFVFALAI PLLYPFLVPLGLHWPLNALMLINIQTLGYDFIQGPMGTWNFACFGATAGVLALSIRDKDTVMRQTAGSALAAGLLGGISE PSLYGIHLRFKRVYPRMLAGCFAGGLTIAVLSTIFEPVTTNAFVFTSIPTMFVFNPAWIYMVSILVAFTVAFLAIFITDY RTTEEKAEFFARRDSADDVPAATVPSATTPAPAAAAANPAGECKVGSPISGEVLPMAEIADPVFSAGTLGDGVGVNPTAT AGAGTEVYSPVSGTVKSAMKSGHAYGIKTDDGVEVLVHIGIDTVQMKGEGFTPAVQKGDRVEAGQKLATVDYDKVRAAGY GTTIVVAVTNTKAMKAVTPTGVKHAGAGDTIFTVTQ >Mature_675_residues STQTREDTARAILDGIGGASNITSFTHCATRLRFELADASKVDKAALDSIPKVMGAVPQGGRNYQVVIGGDVANVYDDMT HLPEMKSAAPSDADIKAAARAKSKGKLPWMDSFFEYLSDSFRPILGVLLGASLIIAFTAVLDAFHIVDFRADDKSASWVF VDAMWRSVFYFLPVMVAFNAGKKLRIDPWVPAAIMFALFTPEFLGLKESSTAECVTNAALGTETCHAPIFGINMTFPDYG GNVFVPLIMAAVAAVVYKGFQKVIPTAVHMVFVPFLTLVIMIPVTAFIIGPFGTWAGNGIGLGLSWMNENAPFVFALAIP LLYPFLVPLGLHWPLNALMLINIQTLGYDFIQGPMGTWNFACFGATAGVLALSIRDKDTVMRQTAGSALAAGLLGGISEP SLYGIHLRFKRVYPRMLAGCFAGGLTIAVLSTIFEPVTTNAFVFTSIPTMFVFNPAWIYMVSILVAFTVAFLAIFITDYR TTEEKAEFFARRDSADDVPAATVPSATTPAPAAAAANPAGECKVGSPISGEVLPMAEIADPVFSAGTLGDGVGVNPTATA GAGTEVYSPVSGTVKSAMKSGHAYGIKTDDGVEVLVHIGIDTVQMKGEGFTPAVQKGDRVEAGQKLATVDYDKVRAAGYG TTIVVAVTNTKAMKAVTPTGVKHAGAGDTIFTVTQ
Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This
COG id: COG1263
COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIC type-1 domain [H]
Homologues:
Organism=Escherichia coli, GI1790159, Length=683, Percent_Identity=30.1610541727672, Blast_Score=291, Evalue=7e-80, Organism=Escherichia coli, GI48994906, Length=494, Percent_Identity=25.5060728744939, Blast_Score=129, Evalue=5e-31, Organism=Escherichia coli, GI2367362, Length=468, Percent_Identity=25.8547008547009, Blast_Score=120, Evalue=2e-28, Organism=Escherichia coli, GI1788757, Length=135, Percent_Identity=34.0740740740741, Blast_Score=98, Evalue=2e-21, Organism=Escherichia coli, GI1786894, Length=156, Percent_Identity=32.6923076923077, Blast_Score=93, Evalue=5e-20, Organism=Escherichia coli, GI1788769, Length=486, Percent_Identity=24.6913580246914, Blast_Score=73, Evalue=5e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011055 - InterPro: IPR018113 - InterPro: IPR001127 - InterPro: IPR001996 - InterPro: IPR003352 - InterPro: IPR013013 [H]
Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 71600; Mature: 71468
Theoretical pI: Translated: 6.02; Mature: 6.02
Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 3.4 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSTQTREDTARAILDGIGGASNITSFTHCATRLRFELADASKVDKAALDSIPKVMGAVPQ CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCCCC GGRNYQVVIGGDVANVYDDMTHLPEMKSAAPSDADIKAAARAKSKGKLPWMDSFFEYLSD CCCEEEEEECCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH SFRPILGVLLGASLIIAFTAVLDAFHIVDFRADDKSASWVFVDAMWRSVFYFLPVMVAFN HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHC AGKKLRIDPWVPAAIMFALFTPEFLGLKESSTAECVTNAALGTETCHAPIFGINMTFPDY CCCEEEECCCCHHHHHHHHHCHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCC GGNVFVPLIMAAVAAVVYKGFQKVIPTAVHMVFVPFLTLVIMIPVTAFIIGPFGTWAGNG CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC IGLGLSWMNENAPFVFALAIPLLYPFLVPLGLHWPLNALMLINIQTLGYDFIQGPMGTWN EEEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHCHHHHCCCCCCCC FACFGATAGVLALSIRDKDTVMRQTAGSALAAGLLGGISEPSLYGIHLRFKRVYPRMLAG EEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHH CFAGGLTIAVLSTIFEPVTTNAFVFTSIPTMFVFNPAWIYMVSILVAFTVAFLAIFITDY HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCC RTTEEKAEFFARRDSADDVPAATVPSATTPAPAAAAANPAGECKVGSPISGEVLPMAEIA CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCEEHHHHH DPVFSAGTLGDGVGVNPTATAGAGTEVYSPVSGTVKSAMKSGHAYGIKTDDGVEVLVHIG CHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHCCCEECCCCCCCCEEEEEEC IDTVQMKGEGFTPAVQKGDRVEAGQKLATVDYDKVRAAGYGTTIVVAVTNTKAMKAVTPT CEEEEECCCCCCHHHCCCCCCCCCCEEEECCHHHHHCCCCCCEEEEEEECCCCEEEECCC GVKHAGAGDTIFTVTQ CCCCCCCCCEEEEECC >Mature Secondary Structure STQTREDTARAILDGIGGASNITSFTHCATRLRFELADASKVDKAALDSIPKVMGAVPQ CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCCCC GGRNYQVVIGGDVANVYDDMTHLPEMKSAAPSDADIKAAARAKSKGKLPWMDSFFEYLSD CCCEEEEEECCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH SFRPILGVLLGASLIIAFTAVLDAFHIVDFRADDKSASWVFVDAMWRSVFYFLPVMVAFN HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHC AGKKLRIDPWVPAAIMFALFTPEFLGLKESSTAECVTNAALGTETCHAPIFGINMTFPDY CCCEEEECCCCHHHHHHHHHCHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCC GGNVFVPLIMAAVAAVVYKGFQKVIPTAVHMVFVPFLTLVIMIPVTAFIIGPFGTWAGNG CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC IGLGLSWMNENAPFVFALAIPLLYPFLVPLGLHWPLNALMLINIQTLGYDFIQGPMGTWN EEEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHCHHHHCCCCCCCC FACFGATAGVLALSIRDKDTVMRQTAGSALAAGLLGGISEPSLYGIHLRFKRVYPRMLAG EEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHH CFAGGLTIAVLSTIFEPVTTNAFVFTSIPTMFVFNPAWIYMVSILVAFTVAFLAIFITDY HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCC RTTEEKAEFFARRDSADDVPAATVPSATTPAPAAAAANPAGECKVGSPISGEVLPMAEIA CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCEEHHHHH DPVFSAGTLGDGVGVNPTATAGAGTEVYSPVSGTVKSAMKSGHAYGIKTDDGVEVLVHIG CHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHCCCEECCCCCCCCEEEEEEC IDTVQMKGEGFTPAVQKGDRVEAGQKLATVDYDKVRAAGYGTTIVVAVTNTKAMKAVTPT CEEEEECCCCCCHHHCCCCCCCCCCEEEECCHHHHHCCCCCCEEEEEEECCCCEEEECCC GVKHAGAGDTIFTVTQ CCCCCCCCCEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8039653; 12948626 [H]