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The map label for this gene is fepD [H]

Identifier: 38233655

GI number: 38233655

Start: 1039729

End: 1040736

Strand: Reverse

Name: fepD [H]

Synonym: DIP1061

Alternate gene names: 38233655

Gene position: 1040736-1039729 (Counterclockwise)

Preceding gene: 38233657

Following gene: 38233654

Centisome position: 41.82

GC content: 54.27

Gene sequence:

>1008_bases
ATGCTTCGACAACCTCGTGTCCGGCTACCATTGCCTTTAGTTATCACTTTCCTTGTAATCATCCTCCTCTGCACGATCAT
TATGAGTTTAGGAGTCGGGGCTCGAAATATTACCTCACCTGACATACTTGCAGCTCTTAGACACTACGGCGACCCAACAA
ACAGCCACATCATCTGGGGACGCCGAATCCCCCGCACGCTCATCGCCATTGCAGCCGGTGCGTCACTGAGCCTCGCAGGT
GTGCTAATTCAAGCATTAACCCGTAATCCCCTAGCGGACACCGGCGTATTCGGCATCAACGCCGGCGCAGCTTTTACCAT
TGTCATCGGCATAGCTCTAGCTGGATCGCTAAGCCACATCAGCATATTCGCGCTCGCGCTACTAGGCGCAATCCTAGCCG
GAGCATGCGTATACGCACTCAGCATGAACTCATGCAAAGGCTCTGACCCCTTACGTCTCGTACTTGCCGGTGTAGCGCTA
AGCGCAATACTCACTGGCATCGGCGACGGCTTATCACTAGTGAATCCCCAAGCATTTGATCGACTCAAAAGCTGGATGGT
CGGCAACATCGACGCCGGTTCTTATCAACCCGCAGCTGTAGCAGGGGTAGGACTAATCCTAGGGATTCTCGTCACTGCAA
CATGCATGAGACAACTCAACGCATTATCCCTAGGAGACGAGTTGGCCATCACCATGGGGGCGTCGATAGCAAAAACTCGG
CTATTCACATTCATCGCAATCGTCGTACTCGCTGCTAGCGCCACTGCCGCAGCCGGGGTAATTACGTTCCTAGGGCTTAT
GGTTCCGCATATCGCACGATGGATCGTAGGCCCCAACCTCCTACGCTTAGTGGCCACCGCATCTCTCATCGGCCCCATCA
TCGTGCTATCAGCCGATATCCTCGGCCGAATCATCGTTCCAGGCGAATTCCCCGCCGGCGTGGTCGTCGCATTCATCGGC
GCACCATTTCTTATCGCTTACGCGCAGACGAAACGCAAGGAGATTTAG

Upstream 100 bases:

>100_bases
AGGGCAAGGAAAGGACGCATTGCTTTCGCACGAGATCGGGATATTTCGAACATGTTGGACAGGTTACCCTAATTTCAAAT
TAATTGGTTAGAATTATCTA

Downstream 100 bases:

>100_bases
CATGCGTGCACTCGTCATACTCTCCTCCCTCCTCCTAGTCACCGCGGCATACAGCTTGGTAATTCCCGGAGCCGGACTAA
GCACTTGGCAGCTTCTCACC

Product: putative iron-siderophore uptake system transmembrane component

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLRQPRVRLPLPLVITFLVIILLCTIIMSLGVGARNITSPDILAALRHYGDPTNSHIIWGRRIPRTLIAIAAGASLSLAG
VLIQALTRNPLADTGVFGINAGAAFTIVIGIALAGSLSHISIFALALLGAILAGACVYALSMNSCKGSDPLRLVLAGVAL
SAILTGIGDGLSLVNPQAFDRLKSWMVGNIDAGSYQPAAVAGVGLILGILVTATCMRQLNALSLGDELAITMGASIAKTR
LFTFIAIVVLAASATAAAGVITFLGLMVPHIARWIVGPNLLRLVATASLIGPIIVLSADILGRIIVPGEFPAGVVVAFIG
APFLIAYAQTKRKEI

Sequences:

>Translated_335_residues
MLRQPRVRLPLPLVITFLVIILLCTIIMSLGVGARNITSPDILAALRHYGDPTNSHIIWGRRIPRTLIAIAAGASLSLAG
VLIQALTRNPLADTGVFGINAGAAFTIVIGIALAGSLSHISIFALALLGAILAGACVYALSMNSCKGSDPLRLVLAGVAL
SAILTGIGDGLSLVNPQAFDRLKSWMVGNIDAGSYQPAAVAGVGLILGILVTATCMRQLNALSLGDELAITMGASIAKTR
LFTFIAIVVLAASATAAAGVITFLGLMVPHIARWIVGPNLLRLVATASLIGPIIVLSADILGRIIVPGEFPAGVVVAFIG
APFLIAYAQTKRKEI
>Mature_335_residues
MLRQPRVRLPLPLVITFLVIILLCTIIMSLGVGARNITSPDILAALRHYGDPTNSHIIWGRRIPRTLIAIAAGASLSLAG
VLIQALTRNPLADTGVFGINAGAAFTIVIGIALAGSLSHISIFALALLGAILAGACVYALSMNSCKGSDPLRLVLAGVAL
SAILTGIGDGLSLVNPQAFDRLKSWMVGNIDAGSYQPAAVAGVGLILGILVTATCMRQLNALSLGDELAITMGASIAKTR
LFTFIAIVVLAASATAAAGVITFLGLMVPHIARWIVGPNLLRLVATASLIGPIIVLSADILGRIIVPGEFPAGVVVAFIG
APFLIAYAQTKRKEI

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=305, Percent_Identity=41.6393442622951, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1790740, Length=286, Percent_Identity=35.6643356643357, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790741, Length=276, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786804, Length=328, Percent_Identity=29.5731707317073, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786347, Length=275, Percent_Identity=30.9090909090909, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788004, Length=228, Percent_Identity=28.5087719298246, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34557; Mature: 34557

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRQPRVRLPLPLVITFLVIILLCTIIMSLGVGARNITSPDILAALRHYGDPTNSHIIWG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEC
RRIPRTLIAIAAGASLSLAGVLIQALTRNPLADTGVFGINAGAAFTIVIGIALAGSLSHI
CCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHCCHHHH
SIFALALLGAILAGACVYALSMNSCKGSDPLRLVLAGVALSAILTGIGDGLSLVNPQAFD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
RLKSWMVGNIDAGSYQPAAVAGVGLILGILVTATCMRQLNALSLGDELAITMGASIAKTR
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHH
LFTFIAIVVLAASATAAAGVITFLGLMVPHIARWIVGPNLLRLVATASLIGPIIVLSADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LGRIIVPGEFPAGVVVAFIGAPFLIAYAQTKRKEI
HCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRQPRVRLPLPLVITFLVIILLCTIIMSLGVGARNITSPDILAALRHYGDPTNSHIIWG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEC
RRIPRTLIAIAAGASLSLAGVLIQALTRNPLADTGVFGINAGAAFTIVIGIALAGSLSHI
CCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHCCHHHH
SIFALALLGAILAGACVYALSMNSCKGSDPLRLVLAGVALSAILTGIGDGLSLVNPQAFD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
RLKSWMVGNIDAGSYQPAAVAGVGLILGILVTATCMRQLNALSLGDELAITMGASIAKTR
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHH
LFTFIAIVVLAASATAAAGVITFLGLMVPHIARWIVGPNLLRLVATASLIGPIIVLSADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LGRIIVPGEFPAGVVVAFIGAPFLIAYAQTKRKEI
HCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 1787794; 9278503 [H]