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The map label for this gene is fepG [H]

Identifier: 38233654

GI number: 38233654

Start: 1038768

End: 1039727

Strand: Reverse

Name: fepG [H]

Synonym: DIP1060

Alternate gene names: 38233654

Gene position: 1039727-1038768 (Counterclockwise)

Preceding gene: 38233655

Following gene: 38233653

Centisome position: 41.78

GC content: 56.77

Gene sequence:

>960_bases
ATGCGTGCACTCGTCATACTCTCCTCCCTCCTCCTAGTCACCGCGGCATACAGCTTGGTAATTCCCGGAGCCGGACTAAG
CACTTGGCAGCTTCTCACCAGCGAAACCCCATTAGCACACACGGTTGTCATGCAGTGGCGCTTGCCTCGAGTGGTCACCG
GAATCCTAGTAGGCGCAGCACTAGCCATAGCAGGATCACTATTCCAATCCCTCACACGCAACCCGCTCGGATCACCTGAC
ATCATCGGATTTTCAACCGGCGCCTACACCGGCGTAATCGCAGCCTTCCTCCTTGGATGGTCAGGCTTTGGTGCCACCAT
TGTCGGTGCGCTCATCGGCGGTCTAGCAGTTTCAGTCGTGGTGATCGCACTGTCAGTCCGAACGCGTATCGACGGCCTCC
GCATCATCCTAGTAGGCCTAGGAATCTCAGCCATGCTCTCGGCCCTCAATAGGTGGCTAATCACCCGCGGAGAACTCGAC
ACAGCACTGTCTGCTGCAAGTTGGGGTGCAGGCTCACTCAATGGACTCCGCTGGACCATAGCGATACCAGCCTGCTGTGT
CCTAGCAATTCTTATCACCACAACCATTCCATTGCGGCGATTCCTCGATGTTCTTAGCCTAGGAGACGATCTCGCTGTAG
GCCTCGGACTTCGATTGCAGTTAACCAAGCTCCTCCTCCTAGTCGGTGGAGTATTCCTCGTGGCAGCAACCACCGCTGTC
GCAGGCCCCATCGCATTTGTGGCTTTGGCGTCTCCACACATTGCCCGTGCACTAACGTCGTCTGCACGAACCCCACTTGT
AGAGACGTCGGTAATCGGCGCTTTGCTTATTATCGTTGCCGACCTCATCGGCCAGCGACTTTTCTATCCCACCCAGCTTC
CTGTTGGCCTCGTCACCGTCACCATCGGTGGCATGTACCTGCTGTGGCTCATAGCCCGCGGCTCGAAGGAGAACTCATGA

Upstream 100 bases:

>100_bases
ATCATCGTTCCAGGCGAATTCCCCGCCGGCGTGGTCGTCGCATTCATCGGCGCACCATTTCTTATCGCTTACGCGCAGAC
GAAACGCAAGGAGATTTAGC

Downstream 100 bases:

>100_bases
CCAGCACTTCCCCCATTCTTCGTACCGATTCCGTCACATTGGCGTGGGATAAGCACACAGTAAGTACTGATCTCACGGTT
GAGGTGCCGCAAGGACAATT

Product: putative iron-siderophore uptake system transmembrane component

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MRALVILSSLLLVTAAYSLVIPGAGLSTWQLLTSETPLAHTVVMQWRLPRVVTGILVGAALAIAGSLFQSLTRNPLGSPD
IIGFSTGAYTGVIAAFLLGWSGFGATIVGALIGGLAVSVVVIALSVRTRIDGLRIILVGLGISAMLSALNRWLITRGELD
TALSAASWGAGSLNGLRWTIAIPACCVLAILITTTIPLRRFLDVLSLGDDLAVGLGLRLQLTKLLLLVGGVFLVAATTAV
AGPIAFVALASPHIARALTSSARTPLVETSVIGALLIIVADLIGQRLFYPTQLPVGLVTVTIGGMYLLWLIARGSKENS

Sequences:

>Translated_319_residues
MRALVILSSLLLVTAAYSLVIPGAGLSTWQLLTSETPLAHTVVMQWRLPRVVTGILVGAALAIAGSLFQSLTRNPLGSPD
IIGFSTGAYTGVIAAFLLGWSGFGATIVGALIGGLAVSVVVIALSVRTRIDGLRIILVGLGISAMLSALNRWLITRGELD
TALSAASWGAGSLNGLRWTIAIPACCVLAILITTTIPLRRFLDVLSLGDDLAVGLGLRLQLTKLLLLVGGVFLVAATTAV
AGPIAFVALASPHIARALTSSARTPLVETSVIGALLIIVADLIGQRLFYPTQLPVGLVTVTIGGMYLLWLIARGSKENS
>Mature_319_residues
MRALVILSSLLLVTAAYSLVIPGAGLSTWQLLTSETPLAHTVVMQWRLPRVVTGILVGAALAIAGSLFQSLTRNPLGSPD
IIGFSTGAYTGVIAAFLLGWSGFGATIVGALIGGLAVSVVVIALSVRTRIDGLRIILVGLGISAMLSALNRWLITRGELD
TALSAASWGAGSLNGLRWTIAIPACCVLAILITTTIPLRRFLDVLSLGDDLAVGLGLRLQLTKLLLLVGGVFLVAATTAV
AGPIAFVALASPHIARALTSSARTPLVETSVIGALLIIVADLIGQRLFYPTQLPVGLVTVTIGGMYLLWLIARGSKENS

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=288, Percent_Identity=45.4861111111111, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI1790740, Length=290, Percent_Identity=31.7241379310345, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786347, Length=280, Percent_Identity=32.1428571428571, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1790741, Length=304, Percent_Identity=32.2368421052632, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1788004, Length=284, Percent_Identity=30.9859154929577, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786805, Length=282, Percent_Identity=34.7517730496454, Blast_Score=94, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33031; Mature: 33031

Theoretical pI: Translated: 10.91; Mature: 10.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALVILSSLLLVTAAYSLVIPGAGLSTWQLLTSETPLAHTVVMQWRLPRVVTGILVGAA
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAIAGSLFQSLTRNPLGSPDIIGFSTGAYTGVIAAFLLGWSGFGATIVGALIGGLAVSVV
HHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VIALSVRTRIDGLRIILVGLGISAMLSALNRWLITRGELDTALSAASWGAGSLNGLRWTI
HHHHHHHHHHCCCEEHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEE
AIPACCVLAILITTTIPLRRFLDVLSLGDDLAVGLGLRLQLTKLLLLVGGVFLVAATTAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGPIAFVALASPHIARALTSSARTPLVETSVIGALLIIVADLIGQRLFYPTQLPVGLVTV
HHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
TIGGMYLLWLIARGSKENS
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRALVILSSLLLVTAAYSLVIPGAGLSTWQLLTSETPLAHTVVMQWRLPRVVTGILVGAA
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAIAGSLFQSLTRNPLGSPDIIGFSTGAYTGVIAAFLLGWSGFGATIVGALIGGLAVSVV
HHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VIALSVRTRIDGLRIILVGLGISAMLSALNRWLITRGELDTALSAASWGAGSLNGLRWTI
HHHHHHHHHHCCCEEHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEE
AIPACCVLAILITTTIPLRRFLDVLSLGDDLAVGLGLRLQLTKLLLLVGGVFLVAATTAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGPIAFVALASPHIARALTSSARTPLVETSVIGALLIIVADLIGQRLFYPTQLPVGLVTV
HHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
TIGGMYLLWLIARGSKENS
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 9278503 [H]