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The map label for this gene is ezrA

Identifier: 15924707

GI number: 15924707

Start: 1836295

End: 1837989

Strand: Reverse

Name: ezrA

Synonym: SAV1717

Alternate gene names: 15924707

Gene position: 1837989-1836295 (Counterclockwise)

Preceding gene: 15924711

Following gene: 15924706

Centisome position: 63.85

GC content: 31.03

Gene sequence:

>1695_bases
ATGGTGTTATATATCATTTTGGCAATAATTGTGATTATATTGATTGCTGTAGGTGTATTATTCTATTTACGTTCAAATAA
ACGACAAATTATTGAAAAAGCAATCGAACGTAAAAATGAAATTGAGACGTTACCTTTTGATCAAAACCTTGCACAATTAT
CTAAGTTGAATTTAAAAGGTGAAACAAAAACGAAATACGATGCAATGAAAAAGGACAACGTAGAAAGTACAAATAAGTAT
CTAGCTCCTGTGGAAGAAAAAATCCATAATGCTGAGGCTTTATTAGATAAATTTAGTTTCAACGCATCTCAAAGTGAAAT
TGATGATGCAAATGAGTTGATGGATAGTTACGAACAAAGCTATCAGCAACAATTAGAAGATGTAAATGAAATTATTGCGT
TATACAAAGATAATGATGAATTATATGACAAATGTAAGGTTGATTATCGTGAAATGAAACGTGATGTTTTAGCAAATCGT
CATCAATTTGGTGAGGCAGCAAGTCTACTTGAAACTGAAATTGAAAAGTTTGAGCCAAGGTTAGAGCAATATGAAGTACT
AAAAGCTGATGGTAATTATGTACAAGCGCACAACCATATAGCTGCCTTGAATGAACAAATGAAACAGCTAAGATCTTATA
TGGAAGAAATACCAGAATTAATTAGAGAAACTCAAAAAGAATTACCTGGTCAATTCCAAGATTTAAAATATGGTTGCCGT
GATCTTAAAGTTGAAGGGTATGATCTGGATCACGTAAAAGTAGACAGTACATTACAAAGCTTAAAAACAGAGCTTAGTTT
CGTTGAACCATTAATTAGCCGCTTAGAATTAGAAGAAGCTAATGATAAACTAGCTAATATCAATGATAAGTTAGATGACA
TGTATGATTTAATTGAACATGAAGTTAAAGCTAAAAATGATGTCGAAGAAACAAAAGATATCATTACGGATAACTTATTC
AAAGCTAAAGACATGAATTATACATTGCAAACAGAAATTGAATATGTACGTGAAAACTACTATATAAATGAATCTGATGC
TCAAAGTGTTCGTCAATTTGAAAATGAAATTCAAAGTTTAATTTCTGTATATGATGATATTTTAAAAGAAATGTCTAAAT
CTGCTGTACGATATAGCGAGGTTCAGGATAATTTACAATATTTAGAAGATCATGTCACAGTTATTAATGACAAACAAGAA
AAGCTACAAAATCATCTGATTCAATTGCGTGAAGATGAAGCAGAAGCAGAAGACAATCTGCTACGAGTACAATCGAAGAA
AGAAGAAGTGTATCGTCGATTACTTGCTTCTAACTTAACAAGCGTTCCTGAAAGGTTTATCATCATGAAAAATGAAATTG
ATCATGAAGTTCGTGATGTTAACGAACAATTTAGTGAACGTCCAATACACGTTAAACAGTTAAAAGATAAAGTGTCTAAA
ATTGTGATTCAAATGAATACATTTGAAGATGAAGCAAATGATGTTCTTGTTAATGCTGTTTATGCAGAGAAATTAATTCA
ATATGGAAATAGATATCGTAAGGACTATAGCAATGTTGATAAGAGCTTAAATGAAGCTGAACGATTATTTAAAAATAATC
GCTATAAGCGTGCGATTGAAATTGCAGAGCAAGTTCTTGAAAGTGTTGAGCCAGGTGTCACTAAACATATTGAAGAAGAA
GTTATTAAGCAATAG

Upstream 100 bases:

>100_bases
TATAGAATTTCGAAAATATTATGGCAATAAATTCATTTTATAATTTATCCTTAAGCAAAATTACGTTATAATAGTAATGA
TAAATTAGGAGGAGAAGCAT

Downstream 100 bases:

>100_bases
AAACTAGTATGTAGTTATACTTAAATAATATGAGCACTCTGTCAAATTGGACTGATGAGTTTAATAATTGAAGTTAGCCA
ACGATACGTTGTCTAGCTTC

Product: septation ring formation regulator EzrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MVLYIILAIIVIILIAVGVLFYLRSNKRQIIEKAIERKNEIETLPFDQNLAQLSKLNLKGETKTKYDAMKKDNVESTNKY
LAPVEEKIHNAEALLDKFSFNASQSEIDDANELMDSYEQSYQQQLEDVNEIIALYKDNDELYDKCKVDYREMKRDVLANR
HQFGEAASLLETEIEKFEPRLEQYEVLKADGNYVQAHNHIAALNEQMKQLRSYMEEIPELIRETQKELPGQFQDLKYGCR
DLKVEGYDLDHVKVDSTLQSLKTELSFVEPLISRLELEEANDKLANINDKLDDMYDLIEHEVKAKNDVEETKDIITDNLF
KAKDMNYTLQTEIEYVRENYYINESDAQSVRQFENEIQSLISVYDDILKEMSKSAVRYSEVQDNLQYLEDHVTVINDKQE
KLQNHLIQLREDEAEAEDNLLRVQSKKEEVYRRLLASNLTSVPERFIIMKNEIDHEVRDVNEQFSERPIHVKQLKDKVSK
IVIQMNTFEDEANDVLVNAVYAEKLIQYGNRYRKDYSNVDKSLNEAERLFKNNRYKRAIEIAEQVLESVEPGVTKHIEEE
VIKQ

Sequences:

>Translated_564_residues
MVLYIILAIIVIILIAVGVLFYLRSNKRQIIEKAIERKNEIETLPFDQNLAQLSKLNLKGETKTKYDAMKKDNVESTNKY
LAPVEEKIHNAEALLDKFSFNASQSEIDDANELMDSYEQSYQQQLEDVNEIIALYKDNDELYDKCKVDYREMKRDVLANR
HQFGEAASLLETEIEKFEPRLEQYEVLKADGNYVQAHNHIAALNEQMKQLRSYMEEIPELIRETQKELPGQFQDLKYGCR
DLKVEGYDLDHVKVDSTLQSLKTELSFVEPLISRLELEEANDKLANINDKLDDMYDLIEHEVKAKNDVEETKDIITDNLF
KAKDMNYTLQTEIEYVRENYYINESDAQSVRQFENEIQSLISVYDDILKEMSKSAVRYSEVQDNLQYLEDHVTVINDKQE
KLQNHLIQLREDEAEAEDNLLRVQSKKEEVYRRLLASNLTSVPERFIIMKNEIDHEVRDVNEQFSERPIHVKQLKDKVSK
IVIQMNTFEDEANDVLVNAVYAEKLIQYGNRYRKDYSNVDKSLNEAERLFKNNRYKRAIEIAEQVLESVEPGVTKHIEEE
VIKQ
>Mature_564_residues
MVLYIILAIIVIILIAVGVLFYLRSNKRQIIEKAIERKNEIETLPFDQNLAQLSKLNLKGETKTKYDAMKKDNVESTNKY
LAPVEEKIHNAEALLDKFSFNASQSEIDDANELMDSYEQSYQQQLEDVNEIIALYKDNDELYDKCKVDYREMKRDVLANR
HQFGEAASLLETEIEKFEPRLEQYEVLKADGNYVQAHNHIAALNEQMKQLRSYMEEIPELIRETQKELPGQFQDLKYGCR
DLKVEGYDLDHVKVDSTLQSLKTELSFVEPLISRLELEEANDKLANINDKLDDMYDLIEHEVKAKNDVEETKDIITDNLF
KAKDMNYTLQTEIEYVRENYYINESDAQSVRQFENEIQSLISVYDDILKEMSKSAVRYSEVQDNLQYLEDHVTVINDKQE
KLQNHLIQLREDEAEAEDNLLRVQSKKEEVYRRLLASNLTSVPERFIIMKNEIDHEVRDVNEQFSERPIHVKQLKDKVSK
IVIQMNTFEDEANDVLVNAVYAEKLIQYGNRYRKDYSNVDKSLNEAERLFKNNRYKRAIEIAEQVLESVEPGVTKHIEEE
VIKQ

Specific function: Negative regulator of ftsZ ring formation; modulates the frequency and position of ftsZ ring formation. Inhibits ftsZ ring formation at polar sites. Interacts either with ftsZ or with one of its binding partners to promote depolymerization

COG id: COG4477

COG function: function code D; Negative regulator of septation ring formation

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein. Note=Colocalized with ftsZ to the nascent septal site (By similarity)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ezrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EZRA_STAA1 (A7X3E7)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442293.1
- ProteinModelPortal:   A7X3E7
- STRING:   A7X3E7
- EnsemblBacteria:   EBSTAT00000004977
- GeneID:   5559040
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1703
- eggNOG:   COG4477
- GeneTree:   EBGT00050000023750
- HOGENOM:   HBG535339
- OMA:   MDIQELH
- ProtClustDB:   PRK04778
- BioCyc:   SAUR418127:SAHV_1703-MONOMER
- HAMAP:   MF_00728
- InterPro:   IPR010379

Pfam domain/function: PF06160 EzrA

EC number: NA

Molecular weight: Translated: 66228; Mature: 66228

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe887b8c)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLYIILAIIVIILIAVGVLFYLRSNKRQIIEKAIERKNEIETLPFDQNLAQLSKLNLKG
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC
ETKTKYDAMKKDNVESTNKYLAPVEEKIHNAEALLDKFSFNASQSEIDDANELMDSYEQS
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHH
YQQQLEDVNEIIALYKDNDELYDKCKVDYREMKRDVLANRHQFGEAASLLETEIEKFEPR
HHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEQYEVLKADGNYVQAHNHIAALNEQMKQLRSYMEEIPELIRETQKELPGQFQDLKYGCR
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHH
DLKVEGYDLDHVKVDSTLQSLKTELSFVEPLISRLELEEANDKLANINDKLDDMYDLIEH
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
EVKAKNDVEETKDIITDNLFKAKDMNYTLQTEIEYVRENYYINESDAQSVRQFENEIQSL
HHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
ISVYDDILKEMSKSAVRYSEVQDNLQYLEDHVTVINDKQEKLQNHLIQLREDEAEAEDNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LRVQSKKEEVYRRLLASNLTSVPERFIIMKNEIDHEVRDVNEQFSERPIHVKQLKDKVSK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IVIQMNTFEDEANDVLVNAVYAEKLIQYGNRYRKDYSNVDKSLNEAERLFKNNRYKRAIE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IAEQVLESVEPGVTKHIEEEVIKQ
HHHHHHHHHCCCHHHHHHHHHHCH
>Mature Secondary Structure
MVLYIILAIIVIILIAVGVLFYLRSNKRQIIEKAIERKNEIETLPFDQNLAQLSKLNLKG
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC
ETKTKYDAMKKDNVESTNKYLAPVEEKIHNAEALLDKFSFNASQSEIDDANELMDSYEQS
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHH
YQQQLEDVNEIIALYKDNDELYDKCKVDYREMKRDVLANRHQFGEAASLLETEIEKFEPR
HHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEQYEVLKADGNYVQAHNHIAALNEQMKQLRSYMEEIPELIRETQKELPGQFQDLKYGCR
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHH
DLKVEGYDLDHVKVDSTLQSLKTELSFVEPLISRLELEEANDKLANINDKLDDMYDLIEH
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
EVKAKNDVEETKDIITDNLFKAKDMNYTLQTEIEYVRENYYINESDAQSVRQFENEIQSL
HHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
ISVYDDILKEMSKSAVRYSEVQDNLQYLEDHVTVINDKQEKLQNHLIQLREDEAEAEDNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LRVQSKKEEVYRRLLASNLTSVPERFIIMKNEIDHEVRDVNEQFSERPIHVKQLKDKVSK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IVIQMNTFEDEANDVLVNAVYAEKLIQYGNRYRKDYSNVDKSLNEAERLFKNNRYKRAIE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IAEQVLESVEPGVTKHIEEEVIKQ
HHHHHHHHHCCCHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA