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The map label for this gene is eiF1A [H]

Identifier: 15899131

GI number: 15899131

Start: 2166139

End: 2166465

Strand: Reverse

Name: eiF1A [H]

Synonym: SSO2375

Alternate gene names: 15899131

Gene position: 2166465-2166139 (Counterclockwise)

Preceding gene: 15899132

Following gene: 15899130

Centisome position: 72.4

GC content: 37.61

Gene sequence:

>327_bases
TTGCCTAAGAAAGATAGAGCGCAGGAAGCACCTAGTAGAGATGTGCCAAGACCCGAAGAGGGACAGACAATATGTGTAGT
TAAGAAGATGTTAGGTGGGGATCACTTAATAGTATTATGTATGGATGGGAAGGAGAGATTAGCGAGAATACCTGGTAAAA
TAAGGAAGAAGATGTGGATGAGAGAAGGAGACGTAGTACTTGTAGGTATTTGGGATTTTCAACCTAATCGTTGTGATATA
TTGTATAAGTATGGAAACGATGAAATAAAAAGACTTGTAAACGAGAATATCATAAGTAGAGAAGTAATTGACCAGTTAAG
AGGATAA

Upstream 100 bases:

>100_bases
GAATTGGAGGATCAACTGCGATTGCGATCGAACTCTTGAAAGAGATGAAGTAATTTTTTATGCATATATGAGAATAGACT
ATTGCAGGTGAATAAATAAG

Downstream 100 bases:

>100_bases
ATTTGACAGAATTACCGAAGAAAACTAAAGATGAAAAAAGACGCAAAGATGAAGATCTTTTTAAAGTAGTAGATTCTACA
ATAGATTATAGGACATATCT

Product: translation initiation factor IF-1A

Products: NA

Alternate protein names: aIF-1A [H]

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MPKKDRAQEAPSRDVPRPEEGQTICVVKKMLGGDHLIVLCMDGKERLARIPGKIRKKMWMREGDVVLVGIWDFQPNRCDI
LYKYGNDEIKRLVNENIISREVIDQLRG

Sequences:

>Translated_108_residues
MPKKDRAQEAPSRDVPRPEEGQTICVVKKMLGGDHLIVLCMDGKERLARIPGKIRKKMWMREGDVVLVGIWDFQPNRCDI
LYKYGNDEIKRLVNENIISREVIDQLRG
>Mature_107_residues
PKKDRAQEAPSRDVPRPEEGQTICVVKKMLGGDHLIVLCMDGKERLARIPGKIRKKMWMREGDVVLVGIWDFQPNRCDIL
YKYGNDEIKRLVNENIISREVIDQLRG

Specific function: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits [H]

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain [H]

Homologues:

Organism=Homo sapiens, GI33356163, Length=85, Percent_Identity=43.5294117647059, Blast_Score=78, Evalue=1e-15,
Organism=Homo sapiens, GI4503499, Length=85, Percent_Identity=42.3529411764706, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17540984, Length=86, Percent_Identity=46.5116279069767, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323916, Length=87, Percent_Identity=43.6781609195402, Blast_Score=87, Evalue=5e-19,
Organism=Drosophila melanogaster, GI45553405, Length=85, Percent_Identity=41.1764705882353, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24647907, Length=85, Percent_Identity=41.1764705882353, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR006196
- InterPro:   IPR001253
- InterPro:   IPR018104
- ProDom:   PD005579 [H]

Pfam domain/function: PF01176 eIF-1a [H]

EC number: NA

Molecular weight: Translated: 12518; Mature: 12387

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50832 S1_IF1_TYPE ; PS01262 IF1A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKKDRAQEAPSRDVPRPEEGQTICVVKKMLGGDHLIVLCMDGKERLARIPGKIRKKMWM
CCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHCCCEEEEEEECCHHHHHHCCHHHHHHHHC
REGDVVLVGIWDFQPNRCDILYKYGNDEIKRLVNENIISREVIDQLRG
CCCCEEEEEEECCCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
PKKDRAQEAPSRDVPRPEEGQTICVVKKMLGGDHLIVLCMDGKERLARIPGKIRKKMWM
CCCCCCCCCCCCCCCCCCCCCEEEEEHHHHCCCEEEEEEECCHHHHHHCCHHHHHHHHC
REGDVVLVGIWDFQPNRCDILYKYGNDEIKRLVNENIISREVIDQLRG
CCCCEEEEEEECCCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA