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The map label for this gene is 15899048

Identifier: 15899048

GI number: 15899048

Start: 2090649

End: 2091539

Strand: Reverse

Name: 15899048

Synonym: SSO2281

Alternate gene names: NA

Gene position: 2091539-2090649 (Counterclockwise)

Preceding gene: 15899049

Following gene: 15899047

Centisome position: 69.9

GC content: 33.67

Gene sequence:

>891_bases
GTGGATGAAATTTACCTTAATTGGGATAAAATGTTTGATGAAGCATTTAGAATTCCCATTCATGAAATTAAGAACGATAA
CATAGTGTTCTCTGGAATTGGCGGGAGTGGAATCGTTGGAGAAATAGCAAACATCTTAGGGGTTGAACTATCCTTTAAGA
GAAAGTTCACGGGAAAAGAGTCACTAATAGCCGTAAGTTATTCTGGGACTACTTCAGAGACGATAAATGATGTAGAAAAT
GCAGTAAAAGCTGGATCTGAAGTTATAATAATAACATCTGGTGGAATACTTGAAAAGTTAGCTAAAGAGAAGAGTTTAAA
ACTTATCAAGATACCTTCGGGTTTTCAGACTAGATACGCTTTCCCATATCTTTTCACACCCTTAATAAAAATGACTACTA
AAAGAAGAGGTATCAAAATAAACGAGATGGAATTAAAAGAAGGAGTAATAGAGGCCAAAGAACAAATAAAGGCCGATGCT
ACACGATTAGCTGAATTACTAATAAACAGAATACCTGTAATTTACTCGTCAAAATACTTAGCAATCGCAAAAAGATTCAA
ACAAGAGATAAATGAGAACGCTAAGCATCCTGCGTTTTATGGCGAAATACCAGAAATAAATCATAATGAAATAGAAAGCT
ATGTTCATGGACCTTCTCTAGTATCAGTCATCGTTGAAAGCTCAGAAATCGACAAAATTACTGAAGATGTATTAAACTCA
ATAGTCATAAAACCATATTTTAATAGTGATGAGAAAAACATTTCTAGTCTACTTGCACTAGCCGGAGTTACATCACTTGA
AATGGCTAAAAAACTTAACGAGAAACCAGATAAGCTGTATAACATACCCAAAGCTAGGCAACTAACTTCAAATTTATTTA
AAATAAACTAG

Upstream 100 bases:

>100_bases
ATAGTACTAAAACAAAACAATAAATCGCTGGGTATAGATACGATAACTATTAATATGTCCTCAAATCCTCCGTCCATGTC
CATATCTGTGGTGATAAAAG

Downstream 100 bases:

>100_bases
TGTGAACAGATAATGGATTTTAGAATTAGGGTATACAATTCGCTTGGGAGAAAGCTAGAGGAATTTGGTACAGTAGAGCC
GAATCTAGTGAAAATGTACG

Product: bifunctional phosphoglucose/phosphomannose isomerase

Products: NA

Alternate protein names: Glucose-6-phosphate isomerase; GPI; Mannose-6-phosphate isomerase; Phosphoglucose isomerase; PGI; Phosphomannose isomerase; PMI

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDEIYLNWDKMFDEAFRIPIHEIKNDNIVFSGIGGSGIVGEIANILGVELSFKRKFTGKESLIAVSYSGTTSETINDVEN
AVKAGSEVIIITSGGILEKLAKEKSLKLIKIPSGFQTRYAFPYLFTPLIKMTTKRRGIKINEMELKEGVIEAKEQIKADA
TRLAELLINRIPVIYSSKYLAIAKRFKQEINENAKHPAFYGEIPEINHNEIESYVHGPSLVSVIVESSEIDKITEDVLNS
IVIKPYFNSDEKNISSLLALAGVTSLEMAKKLNEKPDKLYNIPKARQLTSNLFKIN

Sequences:

>Translated_296_residues
MDEIYLNWDKMFDEAFRIPIHEIKNDNIVFSGIGGSGIVGEIANILGVELSFKRKFTGKESLIAVSYSGTTSETINDVEN
AVKAGSEVIIITSGGILEKLAKEKSLKLIKIPSGFQTRYAFPYLFTPLIKMTTKRRGIKINEMELKEGVIEAKEQIKADA
TRLAELLINRIPVIYSSKYLAIAKRFKQEINENAKHPAFYGEIPEINHNEIESYVHGPSLVSVIVESSEIDKITEDVLNS
IVIKPYFNSDEKNISSLLALAGVTSLEMAKKLNEKPDKLYNIPKARQLTSNLFKIN
>Mature_296_residues
MDEIYLNWDKMFDEAFRIPIHEIKNDNIVFSGIGGSGIVGEIANILGVELSFKRKFTGKESLIAVSYSGTTSETINDVEN
AVKAGSEVIIITSGGILEKLAKEKSLKLIKIPSGFQTRYAFPYLFTPLIKMTTKRRGIKINEMELKEGVIEAKEQIKADA
TRLAELLINRIPVIYSSKYLAIAKRFKQEINENAKHPAFYGEIPEINHNEIESYVHGPSLVSVIVESSEIDKITEDVLNS
IVIKPYFNSDEKNISSLLALAGVTSLEMAKKLNEKPDKLYNIPKARQLTSNLFKIN

Specific function: Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PGI/PMI family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PGMI_SULSO (Q97WE5)

Other databases:

- EMBL:   AE006641
- PIR:   D90398
- RefSeq:   NP_343653.1
- ProteinModelPortal:   Q97WE5
- SMR:   Q97WE5
- GeneID:   1453770
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO2281
- NMPDR:   fig|273057.1.peg.2076
- HOGENOM:   HBG553399
- OMA:   AYRVKNE
- ProtClustDB:   PRK08674
- BioCyc:   SSOL273057:SSO2281-MONOMER
- BRENDA:   5.3.1.8
- BRENDA:   5.3.1.9
- InterPro:   IPR011857
- InterPro:   IPR019490
- TIGRFAMs:   TIGR02128

Pfam domain/function: PF10432 bact-PGI_C

EC number: =5.3.1.9; =5.3.1.8

Molecular weight: Translated: 33142; Mature: 33142

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: ACT_SITE 192-192 ACT_SITE 208-208 ACT_SITE 286-286

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEIYLNWDKMFDEAFRIPIHEIKNDNIVFSGIGGSGIVGEIANILGVELSFKRKFTGKE
CCCEEECHHHHHHHHHCCCHHHCCCCCEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCC
SLIAVSYSGTTSETINDVENAVKAGSEVIIITSGGILEKLAKEKSLKLIKIPSGFQTRYA
CEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCEEEECCCCCCHHEE
FPYLFTPLIKMTTKRRGIKINEMELKEGVIEAKEQIKADATRLAELLINRIPVIYSSKYL
CHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHH
AIAKRFKQEINENAKHPAFYGEIPEINHNEIESYVHGPSLVSVIVESSEIDKITEDVLNS
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
IVIKPYFNSDEKNISSLLALAGVTSLEMAKKLNEKPDKLYNIPKARQLTSNLFKIN
EEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDEIYLNWDKMFDEAFRIPIHEIKNDNIVFSGIGGSGIVGEIANILGVELSFKRKFTGKE
CCCEEECHHHHHHHHHCCCHHHCCCCCEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCC
SLIAVSYSGTTSETINDVENAVKAGSEVIIITSGGILEKLAKEKSLKLIKIPSGFQTRYA
CEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCEEEECCCCCCHHEE
FPYLFTPLIKMTTKRRGIKINEMELKEGVIEAKEQIKADATRLAELLINRIPVIYSSKYL
CHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHH
AIAKRFKQEINENAKHPAFYGEIPEINHNEIESYVHGPSLVSVIVESSEIDKITEDVLNS
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
IVIKPYFNSDEKNISSLLALAGVTSLEMAKKLNEKPDKLYNIPKARQLTSNLFKIN
EEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726