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The map label for this gene is trpB

Identifier: 15926952

GI number: 15926952

Start: 1376947

End: 1378161

Strand: Direct

Name: trpB

Synonym: SA1204

Alternate gene names: 15926952

Gene position: 1376947-1378161 (Clockwise)

Preceding gene: 15926951

Following gene: 15926953

Centisome position: 48.92

GC content: 37.94

Gene sequence:

>1215_bases
ATGAATAAACAAATACAAACAGAAGCAGATGAATTAGGTTTCTTTGGTGAATATGGAGGGCAATATGTTCCAGAAACATT
AATGCCAGCAATTATTGAGTTGAAAAAAGCTTATAAAGAGGCAAAAGCAGACCCAGAGTTTCAAAGAGAACTGGAATACT
ATTTATCAGAGTATGTAGGACGCGCGACACCACTTACATATGCTGCATCATATACTGAAAGCCTAGGTGGCGCTAAAATA
TATTTGAAACGAGAGGATCTAAATCATACAGGCGCCCATAAAATTAATAATGCGTTAGGTCAAGCGTTGCTTGCTAAAAG
AATGGGCAAGAAGAAGCTTGTTGCTGAAACTGGTGCGGGTCAACATGGTGTAGCTAGTGCTACGGTTGCTGCATTATTTG
ATATGGAACTTGTTGTCTTTATGGGAAGTGAAGATATTAAAAGACAACAACTTAATGTATTTAGAATGGAATTACTTGGT
GCAAAGGTTGTGGCAGTTGAAGAAGGTCAAGGGACTTTATCGGATGCAGTTAATAAAGCATTGCAATATTGGGTAAGTCA
TGTAGATGATACACATTATTTATTAGGTTCTGCATTAGGTCCAGACCCATTCCCAACGATTGTTAGAGATTTTCAGAGTG
TCATTGGTAAAGAAATAAAATCACAGATATTGAAGAAAGAAGGTCGACTTCCGGATGCAATTGTAGCATGTATCGGTGGT
GGCTCAAATGCAATCGGTACATTTTATCCATTTATTAAAGATGATGTTGCATTATACGGTGTTGAAGCCGCAGGTCAAGG
CGAGGATACTGATAAACATGCACTTGCAATTGGCAAAGGATCACCTGGCGTATTACATGGTACTAAAATGTATTTAATTC
AAGATGAAGGTGGGCAAGTGCAACTAGCACATTCTATTTCAGCAGGACTTGATTATCCTGGTATTGGGCCTGAACATTCT
TATTACCACGACATTGGTAGAGTAACTTTTGAAAATGCAAGTGATACACAAGCAATGAATGCTTTAATCAACTTTACAAA
ACATGAAGGTATTATACCTGCAATTGAAAGTGCACATGCACTGAGTTATGTTGAAAGACTAGCGCCTACGATGTCGAAAG
AAGATATTATTGTAGTAACTATTTCTGGACGTGGCGATAAAGATATGGAAACAATTAGACAATATATGGCAGAGCGAGGT
CTTGCAAATGACTAA

Upstream 100 bases:

>100_bases
CATCAAGGTTATGATCTTGCATCAGGTATAGAAGTAAATGGGCGAAAAGATATAGAAAAAATGACAGCAATTGTAAATAT
TGTGAAAGGAGATAGAGACA

Downstream 100 bases:

>100_bases
ATTATTTATACCTTATATTATGGGCAATAAAGATTTGATTGAAAATGCAACATTGTTGAGTGAAAATGGTGCAGATATAA
TTGAAATTGGTGTACCTTTC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKI
YLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLG
AKVVAVEEGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
GSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALAIGKGSPGVLHGTKMYLIQDEGGQVQLAHSISAGLDYPGIGPEHS
YYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMAERG
LAND

Sequences:

>Translated_404_residues
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKI
YLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLG
AKVVAVEEGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
GSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALAIGKGSPGVLHGTKMYLIQDEGGQVQLAHSISAGLDYPGIGPEHS
YYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMAERG
LAND
>Mature_404_residues
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKI
YLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLG
AKVVAVEEGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
GSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALAIGKGSPGVLHGTKMYLIQDEGGQVQLAHSISAGLDYPGIGPEHS
YYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMAERG
LAND

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=389, Percent_Identity=49.8714652956298, Blast_Score=404, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6321412, Length=388, Percent_Identity=53.8659793814433, Blast_Score=430, Evalue=1e-121,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_STAA1 (A7X238)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441950.1
- ProteinModelPortal:   A7X238
- SMR:   A7X238
- STRING:   A7X238
- EnsemblBacteria:   EBSTAT00000003587
- GeneID:   5561067
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1360
- eggNOG:   COG0133
- GeneTree:   EBGT00050000024423
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- ProtClustDB:   PRK04346
- BioCyc:   SAUR418127:SAHV_1360-MONOMER
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 43907; Mature: 43907

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVG
CCCCCCCCHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
RATPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAG
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
QHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLGAKVVAVEEGQGTLSDAVNKA
CCCHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHH
LQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
HHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEECC
GSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALAIGKGSPGVLHGTKMYLIQDEGGQV
CCCCCHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEECCCCCCEEECCEEEEEECCCCEE
QLAHSISAGLDYPGIGPEHSYYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHA
EEEEHHHCCCCCCCCCCCCHHHHHHCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMAERGLAND
HHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVG
CCCCCCCCHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
RATPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAG
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
QHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLGAKVVAVEEGQGTLSDAVNKA
CCCHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHH
LQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
HHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEECC
GSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALAIGKGSPGVLHGTKMYLIQDEGGQV
CCCCCHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEECCCCCCEEECCEEEEEECCCCEE
QLAHSISAGLDYPGIGPEHSYYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHA
EEEEHHHCCCCCCCCCCCCHHHHHHCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMAERGLAND
HHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA