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The map label for this gene is trpF

Identifier: 15926951

GI number: 15926951

Start: 1376322

End: 1376954

Strand: Direct

Name: trpF

Synonym: SA1203

Alternate gene names: 15926951

Gene position: 1376322-1376954 (Clockwise)

Preceding gene: 15926950

Following gene: 15926952

Centisome position: 48.9

GC content: 31.6

Gene sequence:

>633_bases
ATGAAATTGAAATTTTGTGGCTTTACATCAATAAAGGATGTTACAGCGGCCAGTCAATTACCTATTGATGCGATAGGTTT
CATCCATTATGAAAAAAGTAAAAGGCATCAAACAATTACCCAAATAAAAAAGTTAGCGTCTGCTGTTCCAAATCATATCG
ATAAAGTATGTGTCATGGTAAATCCTGATTTAACAACAATTGAACACGTATTAAGCAATACGTCAATTAACACAATACAG
TTACACGGCACAGAATCTATTGATTTTATACAGGAAATTAAAAAGAAATATTCAAGCATTAAAATCACTAAAGCTTTAGC
TGCAGATGAAAACATAATCCAAAACATAAATAAATATAAAGGGTTCGTAGATTTATTTATTATCGACACACCCTCAGTGT
CGTATGGTGGTACCGGTCAAACATATGACTGGACTATTTTGAAGCACATAAAAGACATACCTTATTTGATAGCAGGAGGC
ATTAACTCTGAAAATATTCAAACAGTTAATCAACTTAAATTATCACATCAAGGTTATGATCTTGCATCAGGTATAGAAGT
AAATGGGCGAAAAGATATAGAAAAAATGACAGCAATTGTAAATATTGTGAAAGGAGATAGAGACAATGAATAA

Upstream 100 bases:

>100_bases
ATAGTGGTATCGATGGCTTACTAATAGGTGAGGCGCTTATGCGTTGTGACAATCTATCTGAATTTTTACCACAACTGAAA
ATGCAAAAGGTGAAGTCATG

Downstream 100 bases:

>100_bases
ACAAATACAAACAGAAGCAGATGAATTAGGTTTCTTTGGTGAATATGGAGGGCAATATGTTCCAGAAACATTAATGCCAG
CAATTATTGAGTTGAAAAAA

Product: N-(5'-phosphoribosyl)anthranilate isomerase

Products: NA

Alternate protein names: PRAI

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVMVNPDLTTIEHVLSNTSINTIQ
LHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGG
INSENIQTVNQLKLSHQGYDLASGIEVNGRKDIEKMTAIVNIVKGDRDNE

Sequences:

>Translated_210_residues
MKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVMVNPDLTTIEHVLSNTSINTIQ
LHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGG
INSENIQTVNQLKLSHQGYDLASGIEVNGRKDIEKMTAIVNIVKGDRDNE
>Mature_210_residues
MKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVMVNPDLTTIEHVLSNTSINTIQ
LHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGG
INSENIQTVNQLKLSHQGYDLASGIEVNGRKDIEKMTAIVNIVKGDRDNE

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family

Homologues:

Organism=Escherichia coli, GI87081863, Length=204, Percent_Identity=25.9803921568627, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRPF_STAA1 (A7X235)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441949.1
- ProteinModelPortal:   A7X235
- STRING:   A7X235
- EnsemblBacteria:   EBSTAT00000003219
- GeneID:   5561049
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1359
- eggNOG:   COG0135
- GeneTree:   EBGT00050000024828
- HOGENOM:   HBG554803
- OMA:   IQLHGRE
- ProtClustDB:   PRK13958
- BioCyc:   SAUR418127:SAHV_1359-MONOMER
- HAMAP:   MF_00135_B
- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF00697 PRAI; SSF51366 RibP_bind_barrel

EC number: =5.3.1.24

Molecular weight: Translated: 23389; Mature: 23389

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVMV
CEEEECCCCCHHHHHHHHCCCCHHHEEEEECCHHHHHHHHHHHHHHHHCCHHHHEEEEEE
NPDLTTIEHVLSNTSINTIQLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYK
CCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
GFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGGINSENIQTVNQLKLSHQGYD
CEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCCC
LASGIEVNGRKDIEKMTAIVNIVKGDRDNE
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVMV
CEEEECCCCCHHHHHHHHCCCCHHHEEEEECCHHHHHHHHHHHHHHHHCCHHHHEEEEEE
NPDLTTIEHVLSNTSINTIQLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYK
CCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
GFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGGINSENIQTVNQLKLSHQGYD
CEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCCC
LASGIEVNGRKDIEKMTAIVNIVKGDRDNE
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA