Click here to switch to the map view.

The map label for this gene is trpD

Identifier: 15926949

GI number: 15926949

Start: 1374540

End: 1375538

Strand: Direct

Name: trpD

Synonym: SA1201

Alternate gene names: 15926949

Gene position: 1374540-1375538 (Clockwise)

Preceding gene: 15926948

Following gene: 15926950

Centisome position: 48.83

GC content: 33.83

Gene sequence:

>999_bases
ATGACATTACTAACAAGAATAAAAACTGAAACTATATTACTTGAAAGCGACATTAAAGAGCTAATCGATATACTTATTTC
TCCTAGTATTGGAACTGATATTAAATATGAATTACTTAGTTCCTATTCGGAGCGAGAAATCCAACAACAAGAATTAACAT
ATATTGTACGTAGCTTAATTAATACAATGTATCCACATCAACCATGTTATGAAGGGGCTATGTGTGTGTGCGGCACAGGT
GGTGACAAGTCAAATAGTTTCAACATTTCAACGACTGTTGCTTTTGTTGTAGCAAGTGCTGGCGTAAAAGTTATAAAACA
TGGTAATAAAAGTATTACCTCAAATTCAGGTAGTACGGATTTGTTAAATCAAATGAACATACAAACAACAACTGTTGATG
ATACACCTAACCAATTAAATGAAAAAGACCTTGTATTCATTGGTGCAACTGAATCATATCCAATCATGAAGTATATGCAA
CCAGTTAGAAAAATGATTGGAAAGCCTACAATATTAAACCTTGTGGGTCCATTAATTAATCCATATCACTTAACGTATCA
AATGGTAGGCGTCTTTGATCCTACAAAGTTAAAGTTAGTTGCTAAAACGATTAAAGATTTAGGTAGAAAACGTGCAATCG
TTTTACATGGTGCAAATGGTATGGATGAAGCAACACTATCTGGTGATAATTTGATATATGAATTGACTGAAGATGGAGAA
ATCAAAAATTACACATTAAATGCGACTGATTATGGTTTGAAACATGCGCCGAATAGTGATTTTAAAGGCGGTTCACCTGA
AGAAAATTTAGCAATCTCCCTTAATATCTTGAATGGTAAAGATCAGTCAAGTCGACGTGATGTTGTCTTACTAAATGCGG
GTTTAAGCCTTTATGTTGCAGAGAAAGTGGATACCATCGCAGAAGGCATAGAACTTGCAACTACATTGATTGATAATGGT
GAAGCATTGAAAAAATACCATCAAATGAGAGGTGAATAA

Upstream 100 bases:

>100_bases
CGCATTACGGTATTCAGTACCATCCTGAATCATTTGCTACAGACTATGGTGTCAAAATAATTACAAATTTCATTAATCTA
GTGAAGGAAGGATGAAAACC

Downstream 100 bases:

>100_bases
TATGACGATTTTAGCAGAAATTGTTAAATATAAACAGTCACTTTTACAAAATGGCTATTATCAAGACAAACTTAATACCT
TGAAAAGTGTGAAGATTCAG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLINTMYPHQPCYEGAMCVCGTG
GDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTDLLNQMNIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQ
PVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTEDGE
IKNYTLNATDYGLKHAPNSDFKGGSPEENLAISLNILNGKDQSSRRDVVLLNAGLSLYVAEKVDTIAEGIELATTLIDNG
EALKKYHQMRGE

Sequences:

>Translated_332_residues
MTLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLINTMYPHQPCYEGAMCVCGTG
GDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTDLLNQMNIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQ
PVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTEDGE
IKNYTLNATDYGLKHAPNSDFKGGSPEENLAISLNILNGKDQSSRRDVVLLNAGLSLYVAEKVDTIAEGIELATTLIDNG
EALKKYHQMRGE
>Mature_331_residues
TLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLINTMYPHQPCYEGAMCVCGTGG
DKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTDLLNQMNIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQP
VRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTEDGEI
KNYTLNATDYGLKHAPNSDFKGGSPEENLAISLNILNGKDQSSRRDVVLLNAGLSLYVAEKVDTIAEGIELATTLIDNGE
ALKKYHQMRGE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=206, Percent_Identity=42.7184466019417, Blast_Score=153, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320561, Length=263, Percent_Identity=29.277566539924, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_STAA1 (A7X232)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441947.1
- ProteinModelPortal:   A7X232
- SMR:   A7X232
- STRING:   A7X232
- EnsemblBacteria:   EBSTAT00000003637
- GeneID:   5561068
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1357
- eggNOG:   COG0547
- GeneTree:   EBGT00050000024914
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   SAUR418127:SAHV_1357-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF00591 Glycos_transf_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36526; Mature: 36395

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLI
CCHHHEECHHEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTMYPHQPCYEGAMCVCGTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTD
HHHCCCCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHH
LLNQMNIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQPVRKMIGKPTILNLVGPLIN
HHHHCCCEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCC
PYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTEDGE
CEEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCEEEEECCCCC
IKNYTLNATDYGLKHAPNSDFKGGSPEENLAISLNILNGKDQSSRRDVVLLNAGLSLYVA
EEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCEEEEH
EKVDTIAEGIELATTLIDNGEALKKYHQMRGE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLI
CHHHEECHHEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTMYPHQPCYEGAMCVCGTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTD
HHHCCCCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHH
LLNQMNIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQPVRKMIGKPTILNLVGPLIN
HHHHCCCEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCC
PYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTEDGE
CEEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCEEEEECCCCC
IKNYTLNATDYGLKHAPNSDFKGGSPEENLAISLNILNGKDQSSRRDVVLLNAGLSLYVA
EEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCEEEEH
EKVDTIAEGIELATTLIDNGEALKKYHQMRGE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA