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The map label for this gene is trpG

Identifier: 15926948

GI number: 15926948

Start: 1373968

End: 1374534

Strand: Direct

Name: trpG

Synonym: SA1200

Alternate gene names: 15926948

Gene position: 1373968-1374534 (Clockwise)

Preceding gene: 15926947

Following gene: 15926949

Centisome position: 48.81

GC content: 35.45

Gene sequence:

>567_bases
ATGATCTTAGTTGTAGATAATTATGATTCCTTTACATATAACCTAGTGGATATTGTTGCTCAACATACTGACGTCATTGT
TCAATATCCTGATGATGATAATGTGCTGAATCAATCGGTGGACGCTGTTATTATATCTCCTGGTCCAGGGCATCCATTAG
ACGATCAACAGTTAATGAAAATCATATCAACCTATCAACACAAACCCATTTTAGGTATTTGCCTAGGTGCTCAGGCACTG
ACTTGTTATTACGGTGGAGAAGTCATTAAAGGCGACAAGGTTATGCACGGAAAAGTTGATACACTAAAGGTTATATCGCA
TCATCAACATCTGTTATATCAAGATATACCAGAACAGTTTTCAATTATGAGATATCATTCATTAATAAGTAACCCTGACA
ATTTTCCAGAAGAATTGAAAATTACTGGACGTACCGAAGATTGTATACAGTCATTTGAGCATAAAGAAAGACCGCATTAC
GGTATTCAGTACCATCCTGAATCATTTGCTACAGACTATGGTGTCAAAATAATTACAAATTTCATTAATCTAGTGAAGGA
AGGATGA

Upstream 100 bases:

>100_bases
TCAACGTAGAAGCTGGTTGTGGCGTTGTATATGATTCTATTCCTGAAAAAGAACTGAATGAAACGAAATTGAAAGCTAAA
AGCTTATTGGAGGTGAGGCC

Downstream 100 bases:

>100_bases
AAACCATGACATTACTAACAAGAATAAAAACTGAAACTATATTACTTGAAAGCGACATTAAAGAGCTAATCGATATACTT
ATTTCTCCTAGTATTGGAAC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MILVVDNYDSFTYNLVDIVAQHTDVIVQYPDDDNVLNQSVDAVIISPGPGHPLDDQQLMKIISTYQHKPILGICLGAQAL
TCYYGGEVIKGDKVMHGKVDTLKVISHHQHLLYQDIPEQFSIMRYHSLISNPDNFPEELKITGRTEDCIQSFEHKERPHY
GIQYHPESFATDYGVKIITNFINLVKEG

Sequences:

>Translated_188_residues
MILVVDNYDSFTYNLVDIVAQHTDVIVQYPDDDNVLNQSVDAVIISPGPGHPLDDQQLMKIISTYQHKPILGICLGAQAL
TCYYGGEVIKGDKVMHGKVDTLKVISHHQHLLYQDIPEQFSIMRYHSLISNPDNFPEELKITGRTEDCIQSFEHKERPHY
GIQYHPESFATDYGVKIITNFINLVKEG
>Mature_188_residues
MILVVDNYDSFTYNLVDIVAQHTDVIVQYPDDDNVLNQSVDAVIISPGPGHPLDDQQLMKIISTYQHKPILGICLGAQAL
TCYYGGEVIKGDKVMHGKVDTLKVISHHQHLLYQDIPEQFSIMRYHSLISNPDNFPEELKITGRTEDCIQSFEHKERPHY
GIQYHPESFATDYGVKIITNFINLVKEG

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=191, Percent_Identity=35.0785340314136, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787517, Length=194, Percent_Identity=29.8969072164948, Blast_Score=100, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322638, Length=190, Percent_Identity=34.2105263157895, Blast_Score=121, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=33.175355450237, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21370; Mature: 21370

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVVDNYDSFTYNLVDIVAQHTDVIVQYPDDDNVLNQSVDAVIISPGPGHPLDDQQLMK
CEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCHHCCCCCEEEECCCCCCCCCHHHHHH
IISTYQHKPILGICLGAQALTCYYGGEVIKGDKVMHGKVDTLKVISHHQHLLYQDIPEQF
HHHHHCCCCEEEEEECCCEEEEEECCEEEECCEEECCCCHHHHHHHHHHHHHHHHCHHHH
SIMRYHSLISNPDNFPEELKITGRTEDCIQSFEHKERPHYGIQYHPESFATDYGVKIITN
HHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEECCHHHCHHHHHHHHHH
FINLVKEG
HHHHHCCC
>Mature Secondary Structure
MILVVDNYDSFTYNLVDIVAQHTDVIVQYPDDDNVLNQSVDAVIISPGPGHPLDDQQLMK
CEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCHHCCCCCEEEECCCCCCCCCHHHHHH
IISTYQHKPILGICLGAQALTCYYGGEVIKGDKVMHGKVDTLKVISHHQHLLYQDIPEQF
HHHHHCCCCEEEEEECCCEEEEEECCEEEECCEEECCCCHHHHHHHHHHHHHHHHCHHHH
SIMRYHSLISNPDNFPEELKITGRTEDCIQSFEHKERPHYGIQYHPESFATDYGVKIITN
HHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEECCHHHCHHHHHHHHHH
FINLVKEG
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400208; 11337471 [H]