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The map label for this gene is cdsA

Identifier: 15926844

GI number: 15926844

Start: 1249611

End: 1250393

Strand: Direct

Name: cdsA

Synonym: SA1104

Alternate gene names: 15926844

Gene position: 1249611-1250393 (Clockwise)

Preceding gene: 15926843

Following gene: 15926845

Centisome position: 44.39

GC content: 32.44

Gene sequence:

>783_bases
ATGAAAGTTAGAACGCTGACAGCTATTATTGCCTTAATCGTATTCTTGCCTATCTTGTTAAAAGGCGGCCTTGTGTTAAT
GATATTTGCTAATATATTAGCATTGATTGCATTAAAAGAATTGTTGAATATGAATATGATTAAATTTGTTTCAGTTCCTG
GTTTAATTAGTGCAGTTGGTCTTATCATCATTATGTTGCCACAACATGCAGGGCCATGGGTACAAGTAATTCAATTAAAA
AGTTTAATTGCAATGAGCTTTATTGTATTAAGTTATACTGTCTTATCTAAAAACAGATTTAGTTTTATGGATGCTGCATT
TTGCTTAATGTCTGTGGCTTATGTAGGCATTGGTTTTATGTTCTTTTATGAAACGAGATCAGAAGGATTACATTACATAT
TATATGCCTTTTTAATTGTTTGGCTTACAGATACAGGGGCTTACTTATTTGGTAAAATGATGGGCAAACATAAGCTTTGG
CCAGTAATAAGTCCGAATAAGACAATCGAAGGATTCATAGGTGGCTTGTTCTGTAGTTTGATAGTGCCTCTTGCAATGTT
ATATTTTGTAGATTTCAATATGAATGTATGGATATTACTTGGAGTGACATTGATTTTAAGTTTATTTGGTCAATTAGGTG
ATTTAGTGGAATCAGGATTTAAGCGTCATTTCGGCGTTAAAGACTCAGGTCGAATACTACCTGGACACGGTGGTATTTTA
GACCGATTTGACAGCTTTATGTTTGTGTTACCATTATTAAATATTTTATTAATACAATCTTAA

Upstream 100 bases:

>100_bases
ATTATGGCCTGACTTTGACGAAGATGAATTAATTAAATGTATAAAAATTTATCAGTCACGTCAAAGACGCTTTGGCGGAT
TGAGTGAGGAGTAGTATAGT

Downstream 100 bases:

>100_bases
TGCTGAGAACAAATCAATAAACGTAAAGAGGAGTTGCTGAGATAATTTAATGAATCTCAGAACTCCTTTTGAAAATTATA
CGCAATATTAACTTTGAAAA

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKVRTLTAIIALIVFLPILLKGGLVLMIFANILALIALKELLNMNMIKFVSVPGLISAVGLIIIMLPQHAGPWVQVIQLK
SLIAMSFIVLSYTVLSKNRFSFMDAAFCLMSVAYVGIGFMFFYETRSEGLHYILYAFLIVWLTDTGAYLFGKMMGKHKLW
PVISPNKTIEGFIGGLFCSLIVPLAMLYFVDFNMNVWILLGVTLILSLFGQLGDLVESGFKRHFGVKDSGRILPGHGGIL
DRFDSFMFVLPLLNILLIQS

Sequences:

>Translated_260_residues
MKVRTLTAIIALIVFLPILLKGGLVLMIFANILALIALKELLNMNMIKFVSVPGLISAVGLIIIMLPQHAGPWVQVIQLK
SLIAMSFIVLSYTVLSKNRFSFMDAAFCLMSVAYVGIGFMFFYETRSEGLHYILYAFLIVWLTDTGAYLFGKMMGKHKLW
PVISPNKTIEGFIGGLFCSLIVPLAMLYFVDFNMNVWILLGVTLILSLFGQLGDLVESGFKRHFGVKDSGRILPGHGGIL
DRFDSFMFVLPLLNILLIQS
>Mature_260_residues
MKVRTLTAIIALIVFLPILLKGGLVLMIFANILALIALKELLNMNMIKFVSVPGLISAVGLIIIMLPQHAGPWVQVIQLK
SLIAMSFIVLSYTVLSKNRFSFMDAAFCLMSVAYVGIGFMFFYETRSEGLHYILYAFLIVWLTDTGAYLFGKMMGKHKLW
PVISPNKTIEGFIGGLFCSLIVPLAMLYFVDFNMNVWILLGVTLILSLFGQLGDLVESGFKRHFGVKDSGRILPGHGGIL
DRFDSFMFVLPLLNILLIQS

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family

Homologues:

Organism=Escherichia coli, GI87081696, Length=137, Percent_Identity=43.7956204379562, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1787677, Length=110, Percent_Identity=42.7272727272727, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDSA_STAAC (Q5HGH0)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_186137.1
- STRING:   Q5HGH0
- EnsemblBacteria:   EBSTAT00000008487
- GeneID:   3238386
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL1280
- TIGR:   SACOL1280
- eggNOG:   COG0575
- GeneTree:   EBGT00050000025310
- HOGENOM:   HBG732679
- OMA:   YLAAIRN
- ProtClustDB:   CLSK885236
- BioCyc:   SAUR93062:SACOL1280-MONOMER
- InterPro:   IPR000374

Pfam domain/function: PF01148 CTP_transf_1

EC number: =2.7.7.41

Molecular weight: Translated: 28965; Mature: 28965

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe0c38b8)-; HASH(0xe383304)-; HASH(0xdde3f4c)-; HASH(0xdf2517c)-; HASH(0xdd1df00)-; HASH(0xe3cc0b8)-; HASH(0xcef865c)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRTLTAIIALIVFLPILLKGGLVLMIFANILALIALKELLNMNMIKFVSVPGLISAVG
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHH
LIIIMLPQHAGPWVQVIQLKSLIAMSFIVLSYTVLSKNRFSFMDAAFCLMSVAYVGIGFM
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
FFYETRSEGLHYILYAFLIVWLTDTGAYLFGKMMGKHKLWPVISPNKTIEGFIGGLFCSL
HHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
IVPLAMLYFVDFNMNVWILLGVTLILSLFGQLGDLVESGFKRHFGVKDSGRILPGHGGIL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHH
DRFDSFMFVLPLLNILLIQS
HHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MKVRTLTAIIALIVFLPILLKGGLVLMIFANILALIALKELLNMNMIKFVSVPGLISAVG
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHH
LIIIMLPQHAGPWVQVIQLKSLIAMSFIVLSYTVLSKNRFSFMDAAFCLMSVAYVGIGFM
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
FFYETRSEGLHYILYAFLIVWLTDTGAYLFGKMMGKHKLWPVISPNKTIEGFIGGLFCSL
HHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
IVPLAMLYFVDFNMNVWILLGVTLILSLFGQLGDLVESGFKRHFGVKDSGRILPGHGGIL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHH
DRFDSFMFVLPLLNILLIQS
HHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA