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The map label for this gene is sdhB

Identifier: 15926733

GI number: 15926733

Start: 1129792

End: 1130607

Strand: Direct

Name: sdhB

Synonym: SA0996

Alternate gene names: 15926733

Gene position: 1129792-1130607 (Clockwise)

Preceding gene: 15926732

Following gene: 15926734

Centisome position: 40.14

GC content: 35.29

Gene sequence:

>816_bases
ATGACTGAACAATCAGTGAAAAACACTCCACAACATGAAACACAATCTAAACCGAAACAAAAAACAGTAAAATTAATTAT
TAAACGACAAGATACAAGTGATTCTAAGCCTTATGAAGAAACATTTGAAATTCCATATCGTGAAAATTTAAACGTCATTG
CTTGTTTAATGGAAATTAGACGTAACCCAGTTAATATTAAAGGTGAAAAAACAACACCTGTTGTCTGGGATATGAACTGC
TTAGAAGAAGTATGTGGAGCATGTTCTATGGTTATCAATGGTCGTGCAAGACAATCTTGTTCTGCGATTGTTGATCAATT
AGAACAACCTATTCGTTTAGAGCCAATGAATACTTTCCCAGTTATCCGTGACTTACAAGTTGATCGTTCTAGAATGTTCG
ATAACTTAAAACGTATGAAAGCATGGATCCCAATTGATGGAACGTATGATTTAGGTCCGGGACCACGTATGCCAGAGAAA
AAACGTCAAACAGCTTATGAATTATCTAAATGTATGACATGTGGTGTATGTTTAGAGGTTTGTCCTAATGTTACTGAAAA
TAATAAATTCGTTGGTGCACAAGCAATCTCGCAAGTTCGTTTGTTTAATTTGCACCCAACAGGATCTATGACTAAAGATG
AACGTTTAAATGCATTAATGGGTACTGGTGGCTTACAGCAGTGTGGTAATTCACAAAACTGTGTTAATGCTTGCCCTAAA
GGTATTCCATTAACAACATCCATTGCAGCAATGAACAGAGAAACAACATTCCACATGTTTAAATCATTCTTTGGTTCAGA
CCATGAAGTAGAATAA

Upstream 100 bases:

>100_bases
CATTTGAAAAACCACAGTTTACTTATGATGACGTCGATGTGAGTTTAATACCACCTCGTAAACGTGATTACACAAGTAAG
TCTAAAGGGGGTAAAAAATA

Downstream 100 bases:

>100_bases
AAATTAATCCCTTTTGAGTTAAAATGTTATGTTCCTTTCAAAATTAAATTGAATGGAGATACACAATAACTTGGAAGGGA
TTTTTTTAATAAGCAGATTA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTEQSVKNTPQHETQSKPKQKTVKLIIKRQDTSDSKPYEETFEIPYRENLNVIACLMEIRRNPVNIKGEKTTPVVWDMNC
LEEVCGACSMVINGRARQSCSAIVDQLEQPIRLEPMNTFPVIRDLQVDRSRMFDNLKRMKAWIPIDGTYDLGPGPRMPEK
KRQTAYELSKCMTCGVCLEVCPNVTENNKFVGAQAISQVRLFNLHPTGSMTKDERLNALMGTGGLQQCGNSQNCVNACPK
GIPLTTSIAAMNRETTFHMFKSFFGSDHEVE

Sequences:

>Translated_271_residues
MTEQSVKNTPQHETQSKPKQKTVKLIIKRQDTSDSKPYEETFEIPYRENLNVIACLMEIRRNPVNIKGEKTTPVVWDMNC
LEEVCGACSMVINGRARQSCSAIVDQLEQPIRLEPMNTFPVIRDLQVDRSRMFDNLKRMKAWIPIDGTYDLGPGPRMPEK
KRQTAYELSKCMTCGVCLEVCPNVTENNKFVGAQAISQVRLFNLHPTGSMTKDERLNALMGTGGLQQCGNSQNCVNACPK
GIPLTTSIAAMNRETTFHMFKSFFGSDHEVE
>Mature_270_residues
TEQSVKNTPQHETQSKPKQKTVKLIIKRQDTSDSKPYEETFEIPYRENLNVIACLMEIRRNPVNIKGEKTTPVVWDMNCL
EEVCGACSMVINGRARQSCSAIVDQLEQPIRLEPMNTFPVIRDLQVDRSRMFDNLKRMKAWIPIDGTYDLGPGPRMPEKK
RQTAYELSKCMTCGVCLEVCPNVTENNKFVGAQAISQVRLFNLHPTGSMTKDERLNALMGTGGLQQCGNSQNCVNACPKG
IPLTTSIAAMNRETTFHMFKSFFGSDHEVE

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=246, Percent_Identity=24.7967479674797, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1790596, Length=232, Percent_Identity=24.1379310344828, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786943, Length=189, Percent_Identity=30.1587301587302, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322987, Length=247, Percent_Identity=24.6963562753036, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24643156, Length=230, Percent_Identity=26.9565217391304, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17137106, Length=256, Percent_Identity=24.21875, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 30584; Mature: 30452

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
9.2 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQSVKNTPQHETQSKPKQKTVKLIIKRQDTSDSKPYEETFEIPYRENLNVIACLMEIR
CCCCCCCCCCCHHHHCCHHHHHHHHHEEECCCCCCCCCHHHHCCCCCCCCHHHHHHHHHH
RNPVNIKGEKTTPVVWDMNCLEEVCGACSMVINGRARQSCSAIVDQLEQPIRLEPMNTFP
CCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCCC
VIRDLQVDRSRMFDNLKRMKAWIPIDGTYDLGPGPRMPEKKRQTAYELSKCMTCGVCLEV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
CPNVTENNKFVGAQAISQVRLFNLHPTGSMTKDERLNALMGTGGLQQCGNSQNCVNACPK
CCCCCCCCEEEHHHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCHHHCCCCCHHHHHCCC
GIPLTTSIAAMNRETTFHMFKSFFGSDHEVE
CCCCCHHHHHHCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TEQSVKNTPQHETQSKPKQKTVKLIIKRQDTSDSKPYEETFEIPYRENLNVIACLMEIR
CCCCCCCCCCHHHHCCHHHHHHHHHEEECCCCCCCCCHHHHCCCCCCCCHHHHHHHHHH
RNPVNIKGEKTTPVVWDMNCLEEVCGACSMVINGRARQSCSAIVDQLEQPIRLEPMNTFP
CCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCCC
VIRDLQVDRSRMFDNLKRMKAWIPIDGTYDLGPGPRMPEKKRQTAYELSKCMTCGVCLEV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
CPNVTENNKFVGAQAISQVRLFNLHPTGSMTKDERLNALMGTGGLQQCGNSQNCVNACPK
CCCCCCCCEEEHHHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCHHHCCCCCHHHHHCCC
GIPLTTSIAAMNRETTFHMFKSFFGSDHEVE
CCCCCHHHHHHCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]