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The map label for this gene is murI

Identifier: 15926734

GI number: 15926734

Start: 1130843

End: 1131643

Strand: Direct

Name: murI

Synonym: SA0997

Alternate gene names: 15926734

Gene position: 1130843-1131643 (Clockwise)

Preceding gene: 15926733

Following gene: 15926735

Centisome position: 40.17

GC content: 36.33

Gene sequence:

>801_bases
ATGAATAAACCAATAGGTGTAATAGACTCTGGTGTCGGAGGTTTGACAGTAGCTAAAGAAATTATGCGTCAGTTGCCAAA
TGAGACGATTTATTACTTAGGTGATATTGGACGATGTCCATATGGGCCAAGACCAGGAGAACAAGTAAAACAATATACAG
TTGAAATCGCTCGTAAATTAATGGAATTTGATATAAAAATGCTCGTGATTGCTTGTAATACAGCAACTGCTGTAGCTTTA
GAATATTTACAAAAGACCTTATCAATCCCAGTGATTGGTGTAATTGAACCAGGTGCTAGAACAGCAATAATGACTACTAG
AAATCAAAATGTATTAGTACTAGGAACTGAAGGCACAATTAAATCTGAAGCATATCGTACGCATATTAAACGTATCAATC
CACATGTAGAGGTACATGGCGTTGCCTGTCCAGGTTTTGTGCCACTTGTAGAACAAATGAGATATAGTGATCCAACAATT
ACAAGCATTGTCATTCATCAAACACTGAAACGTTGGCGTAATAGTGAGTCTGATACTGTCATTTTAGGATGTACCCACTA
TCCATTGCTCTATAAACCTATCTATGATTATTTTGGTGGTAAAAAGACAGTGATTTCGTCTGGATTAGAAACGGCTCGTG
AAGTTAGTGCATTGCTAACATTTAGTAATGAACATGCAAGTTATACTGAACATCCAGATCATCGATTTTTTGCAACAGGT
GATCCTACTCACATTACTAACATTATCAAAGAGTGGTTAAATTTATCTGTCAATGTGGAACGTATATCAGTGAATGACTA
G

Upstream 100 bases:

>100_bases
TATTATAATGACAAAAATGGTAAACACAGTGCATAATACTAAAATCCAATGCTTAGTTATGATAAACTAAAAATTAAATT
AAAAGTAAGGATGACCGAAT

Downstream 100 bases:

>100_bases
GAGGATTTTTAATGAAAGAGATTGTTATTGCATCGAATAATCAAGGGAAAATAAATGACTTTAAAGTAATATTTCCAGAT
TACCACGTAATAGGTATTTC

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVAL
EYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTI
TSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATG
DPTHITNIIKEWLNLSVNVERISVND

Sequences:

>Translated_266_residues
MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVAL
EYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTI
TSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATG
DPTHITNIIKEWLNLSVNVERISVND
>Mature_266_residues
MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVAL
EYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTI
TSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATG
DPTHITNIIKEWLNLSVNVERISVND

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=232, Percent_Identity=32.3275862068966, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_STAA1 (A7X179)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441731.1
- ProteinModelPortal:   A7X179
- SMR:   A7X179
- STRING:   A7X179
- EnsemblBacteria:   EBSTAT00000003558
- GeneID:   5559818
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1141
- eggNOG:   COG0796
- GeneTree:   EBGT00050000025302
- HOGENOM:   HBG645102
- OMA:   CGHIPYG
- ProtClustDB:   PRK00865
- BioCyc:   SAUR418127:SAHV_1141-MONOMER
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 29699; Mature: 29699

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKL
CCCCCCEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
MEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTI
HHHCEEEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCEEEEECCCCC
KSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTITSIVIHQTLKRWRNSESDTV
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEE
ILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATG
EEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEECC
DPTHITNIIKEWLNLSVNVERISVND
CCHHHHHHHHHHHCCEEEEEEEECCC
>Mature Secondary Structure
MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKL
CCCCCCEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
MEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTI
HHHCEEEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCEEEEECCCCC
KSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTITSIVIHQTLKRWRNSESDTV
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEE
ILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATG
EEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEECC
DPTHITNIIKEWLNLSVNVERISVND
CCHHHHHHHHHHHCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA