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The map label for this gene is purE [H]

Identifier: 15926650

GI number: 15926650

Start: 1041604

End: 1042086

Strand: Direct

Name: purE [H]

Synonym: SA0916

Alternate gene names: 15926650

Gene position: 1041604-1042086 (Clockwise)

Preceding gene: 15926643

Following gene: 15926651

Centisome position: 37.0

GC content: 38.3

Gene sequence:

>483_bases
GTGAAAGTAGCAGTCATTATGGGCAGTTCTTCCGATTGGAAAATTATGCAAGAGAGTTGTAACATGTTGGATTATTTTGA
AATTCCGTACGAAAAACAAGTAGTATCCGCACATCGTACGCCAAAAATGATGGTTCAATTTGCTTCTGAAGCGAGAGAAA
GAGGTATAAACATTATCATTGCAGGCGCTGGCGGTGCGGCACATTTACCAGGTATGGTTGCATCATTAACGACGCTACCA
GTTATTGGTGTGCCGATTGAAACAAAAAGTTTAAAGGGTATAGATTCTTTATTATCAATTGTTCAAATGCCAGGAGGTAT
TCCGGTTGCAACGACTGCAATTGGTGCAGCAGGTGCTAAAAACGCAGGTATACTTGCAGCAAGAATGTTAAGTATTCAAA
ATCCTTCTTTAGTTGAAAAACTAAATCAGTATGAATCTTCGTTAATTCAAAAAGTGGAGGACATGCAAAATGAACTTCAA
TAA

Upstream 100 bases:

>100_bases
TTCGATTTTTGATTGAAAAAGCAGAAATTGCTTGTTATGCTATATCTATAATATACAACTAAAGTAATTCACAATTCAAA
CTTTTGAAAGGGTGTACAAA

Downstream 100 bases:

>100_bases
ATTAAAGTTTGGTGCGACTATTGGCATTATTGGTGGTGGTCAGCTTGGAAAGATGATGGCACAATCAGCTCAAAAAATGG
GTTATAAAGTGGTTGTATTG

Product: hypothetical protein

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMMVQFASEARERGINIIIAGAGGAAHLPGMVASLTTLP
VIGVPIETKSLKGIDSLLSIVQMPGGIPVATTAIGAAGAKNAGILAARMLSIQNPSLVEKLNQYESSLIQKVEDMQNELQ

Sequences:

>Translated_160_residues
MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMMVQFASEARERGINIIIAGAGGAAHLPGMVASLTTLP
VIGVPIETKSLKGIDSLLSIVQMPGGIPVATTAIGAAGAKNAGILAARMLSIQNPSLVEKLNQYESSLIQKVEDMQNELQ
>Mature_160_residues
MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMMVQFASEARERGINIIIAGAGGAAHLPGMVASLTTLP
VIGVPIETKSLKGIDSLLSIVQMPGGIPVATTAIGAAGAKNAGILAARMLSIQNPSLVEKLNQYESSLIQKVEDMQNELQ

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=151, Percent_Identity=50.9933774834437, Blast_Score=139, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6324702, Length=142, Percent_Identity=54.2253521126761, Blast_Score=154, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 17069; Mature: 17069

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMMVQFASEARERGINIII
CEEEEEECCCCCHHHHHHHCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEE
AGAGGAAHLPGMVASLTTLPVIGVPIETKSLKGIDSLLSIVQMPGGIPVATTAIGAAGAK
ECCCCCHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCC
NAGILAARMLSIQNPSLVEKLNQYESSLIQKVEDMQNELQ
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMMVQFASEARERGINIII
CEEEEEECCCCCHHHHHHHCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEE
AGAGGAAHLPGMVASLTTLPVIGVPIETKSLKGIDSLLSIVQMPGGIPVATTAIGAAGAK
ECCCCCHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCC
NAGILAARMLSIQNPSLVEKLNQYESSLIQKVEDMQNELQ
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]