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The map label for this gene is hslO

Identifier: 15926189

GI number: 15926189

Start: 543205

End: 544086

Strand: Direct

Name: hslO

Synonym: SA0470

Alternate gene names: 15926189

Gene position: 543205-544086 (Clockwise)

Preceding gene: 15926188

Following gene: 15926190

Centisome position: 19.3

GC content: 36.51

Gene sequence:

>882_bases
ATGACACACGATTATATTGTTAAAGCATTAGCATTTGATGGGGAGATTAGGGCTTATGCTGCTTTGACAACTGAAACTGT
TCAAGAAGCACAAACGAGACATTATACATGGCCGACAGCATCTGCTGCAATGGGAAGAACAATGACAGCAACAGCTATGA
TGGGCGCAATGTTGAAAGGTGATCAAAAATTAACTGTCACTGTAGATGGCCAAGGACCTATTGGACGAATTATTGCCGAT
GCAAATGCTAAAGGCGAGGTGCGTGCTTATGTAGACCATCCACAAACTCATTTTCCATTAAATGAGCAAGGTAAACTTGA
TGTAAGACGAGCAGTAGGGACAAATGGATCTATTATAGTTGTTAAAGACGTTGGAATGAAAGACTATTTCTCTGGAGCAA
GTCCAATTGTTTCAGGAGAACTTGGTGAAGATTTTACTTATTATTATGCTACAAGTGAACAAACACCTTCATCGGTAGGT
CTTGGTGTATTGGTAAATCCTGATAATACGATTAAAGCAGCAGGAGGATTTATCATTCAAGTTATGCCAGGTGCCAAAGA
TGAAACAATTTCAAAATTAGAAAAAGCAATTAGTGAAATGACACCAGTTTCTAAATTAATTGAACAAGGATTAACGCCAG
AAGGATTACTAAACGAAATCTTAGGTGAAGACCATGTGCAAATTTTAGAGAAAATGCCTGTTCAATTTGAATGTAATTGT
AGTCATGAGAAATTTTTAAATGCTATTAAAGGATTGGGCGAGGCTGAGATTCAAAATATGATTAAAGAAGATCATGGTGC
TGAAGCAGTATGTCATTTCTGTGGAAATAAATATAAATATACTGAAGAAGAATTAAACGTGTTGCTAGAAAGTTTAGCGT
AA

Upstream 100 bases:

>100_bases
ACTTCATTATTTAGAATGATGGGTGTAGAATAAGTACAATTGTTGCATTTTATGAAGTAAAGTAATTTTAAAATATAGAG
TAATAGAGGAGATTGAAATA

Downstream 100 bases:

>100_bases
TTTAATTTAAATCAATACGCTAAAATGTTTATTTTTAGCGGTTTAGTGAAATGTAGAACTAAATAGTTGTATAATCCTTA
GTGATTTTGTTTGCTTTCTA

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTHDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAMGRTMTATAMMGAMLKGDQKLTVTVDGQGPIGRIIAD
ANAKGEVRAYVDHPQTHFPLNEQGKLDVRRAVGTNGSIIVVKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVG
LGVLVNPDNTIKAAGGFIIQVMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLNEILGEDHVQILEKMPVQFECNC
SHEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGNKYKYTEEELNVLLESLA

Sequences:

>Translated_293_residues
MTHDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAMGRTMTATAMMGAMLKGDQKLTVTVDGQGPIGRIIAD
ANAKGEVRAYVDHPQTHFPLNEQGKLDVRRAVGTNGSIIVVKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVG
LGVLVNPDNTIKAAGGFIIQVMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLNEILGEDHVQILEKMPVQFECNC
SHEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGNKYKYTEEELNVLLESLA
>Mature_292_residues
THDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAMGRTMTATAMMGAMLKGDQKLTVTVDGQGPIGRIIADA
NAKGEVRAYVDHPQTHFPLNEQGKLDVRRAVGTNGSIIVVKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVGL
GVLVNPDNTIKAAGGFIIQVMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLNEILGEDHVQILEKMPVQFECNCS
HEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGNKYKYTEEELNVLLESLA

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=282, Percent_Identity=26.241134751773, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_STAA1 (A7WYS1)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441099.1
- ProteinModelPortal:   A7WYS1
- SMR:   A7WYS1
- STRING:   A7WYS1
- EnsemblBacteria:   EBSTAT00000004315
- GeneID:   5559344
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0509
- eggNOG:   COG1281
- GeneTree:   EBGT00050000024769
- HOGENOM:   HBG286231
- OMA:   AMTIDQG
- ProtClustDB:   PRK00114
- BioCyc:   SAUR418127:SAHV_0509-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 31805; Mature: 31673

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAMGRTMTATAMMGAMLKG
CCHHHEEHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHCC
DQKLTVTVDGQGPIGRIIADANAKGEVRAYVDHPQTHFPLNEQGKLDVRRAVGTNGSIIV
CCEEEEEECCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCEEHHHHCCCCCCEEE
VKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVGLGVLVNPDNTIKAAGGFIIQ
EEECCCHHHHCCCCCCEECCCCCCEEEEEEECCCCCCCCCEEEEECCCCCEEECCCEEEE
VMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLNEILGEDHVQILEKMPVQFECNC
ECCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCCCEEEECC
SHEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGNKYKYTEEELNVLLESLA
CHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
THDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAMGRTMTATAMMGAMLKG
CHHHEEHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHCC
DQKLTVTVDGQGPIGRIIADANAKGEVRAYVDHPQTHFPLNEQGKLDVRRAVGTNGSIIV
CCEEEEEECCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCEEHHHHCCCCCCEEE
VKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVGLGVLVNPDNTIKAAGGFIIQ
EEECCCHHHHCCCCCCEECCCCCCEEEEEEECCCCCCCCCEEEEECCCCCEEECCCEEEE
VMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLNEILGEDHVQILEKMPVQFECNC
ECCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCCCEEEECC
SHEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGNKYKYTEEELNVLLESLA
CHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA