Click here to switch to the map view.

The map label for this gene is vicR

Identifier: 15925723

GI number: 15925723

Start: 24928

End: 25635

Strand: Direct

Name: vicR

Synonym: SA0017

Alternate gene names: 15925723

Gene position: 24928-25635 (Clockwise)

Preceding gene: 15925722

Following gene: 15925724

Centisome position: 0.89

GC content: 36.44

Gene sequence:

>708_bases
ATGCAAATGGCTAGAAAAGTTGTTGTAGTTGATGATGAAAAACCGATTGCTGATATTTTAGAATTTAACTTAAAAAAAGA
AGGATACGATGTGTACTGTGCATACGATGGTAATGATGCAGTCGACTTAATTTATGAAGAAGAACCAGACATCGTATTAC
TAGATATCATGTTACCTGGTCGTGATGGTATGGAAGTATGTCGTGAAGTGCGCAAAAAATACGAAATGCCAATAATAATG
CTTACTGCTAAAGATTCAGAAATTGATAAAGTGCTTGGTTTAGAACTAGGTGCAGATGACTATGTAACGAAACCGTTTAG
TACGCGTGAATTAATCGCACGTGTGAAAGCGAACTTACGTCGTCATTACTCACAACCAGCACAAGACACTGGAAATGTAA
CGAATGAAATCACAATTAAAGATATTGTGATTTATCCAGACGCATATTCTATTAAAAAACGTGGCGAAGATATTGAATTA
ACACATCGTGAATTTGAATTGTTCCATTATTTATCAAAACATATGGGACAAGTAATGACACGTGAACATTTATTACAAAC
AGTATGGGGCTATGATTACTTTGGCGATGTACGTACGGTCGATGTAACGATTCGTCGTTTACGTGAAAAGATTGAAGATG
ATCCGTCACATCCTGAATATATTGTGACGCGTAGAGGCGTTGGATATTTCCTCCAACAACATGAGTAG

Upstream 100 bases:

>100_bases
ACAAAAATAGTAAGCGACATCCTGTGATTTTTTACACAAACATAAACGATAAAGAACAAAAAATGATAAAATAATATTAA
TGATTTAAGAAAAGAGGTTT

Downstream 100 bases:

>100_bases
AGGTCGAAACGAATGAAGTGGCTAAAACAACTACAATCCCTTCATACTAAACTTGTAATTGTTTATGTATTACTGATTAT
CATTGGTATGCAAATTATCG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MQMARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIM
LTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIEL
THREFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE

Sequences:

>Translated_235_residues
MQMARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIM
LTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIEL
THREFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE
>Mature_235_residues
MQMARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIM
LTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIEL
THREFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=39.1304347826087, Blast_Score=168, Evalue=2e-43,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=40.5286343612335, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=36.9565217391304, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=35.7142857142857, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=37.3333333333333, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=35.5263157894737, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=35.6521739130435, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=33.9285714285714, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=34.7639484978541, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790860, Length=239, Percent_Identity=37.6569037656904, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=35.3191489361702, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=31.4410480349345, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=31.6017316017316, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=32.3144104803493, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=34.8214285714286, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790299, Length=143, Percent_Identity=32.1678321678322, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27452; Mature: 27452

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPG
CCCCCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCEEEEEEEECC
RDGMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLR
CCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHH
RHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQVMT
HHCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHH
REHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHCCCC
>Mature Secondary Structure
MQMARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPG
CCCCCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCEEEEEEEECC
RDGMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLR
CCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHH
RHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQVMT
HHCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHH
REHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA