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The map label for this gene is dtd [H]

Identifier: 15675771

GI number: 15675771

Start: 1648661

End: 1649104

Strand: Reverse

Name: dtd [H]

Synonym: SPy_1980

Alternate gene names: 15675771

Gene position: 1649104-1648661 (Counterclockwise)

Preceding gene: 15675772

Following gene: 15675769

Centisome position: 89.02

GC content: 43.02

Gene sequence:

>444_bases
ATGAAACTTGTCTTGCAACGGGTCAAAGAGGCCTCTGTTTCTATTGATGGGAAAATTGCTGGCGCTATTAATCAAGGGTT
GTTGTTGTTAGTAGGTGTGGGACCAGATGATAATGCAGAAGATTTGGCTTACGCTGTGCGAAAAATAGTCAACATGCGCA
TTTTTTCAGATGCTGATGGCAAGATGAACCAGTCTATCCAAGACATCAAGGGCAGTATCTTATCTGTGTCGCAATTTACC
CTTTATGCTGACACCAAAAAGGGAAACCGTCCTGCCTTTACTGGTGCTGCTAAGCCAGATTTGGCTAGTCAGTTGTATGA
TAGCTTTAATGAACAATTGGCAGAGTTTGTGCCAGTTGAGCGTGGCGTTTTTGGGGCAGATATGCAGGTTAGTCTCATCA
ATGATGGACCAGTTACGATTATTTTAGACACGAAATGTCACTAG

Upstream 100 bases:

>100_bases
TTCCAAATCTGACGCATCTGACCACTGTTGTCGAAAAAATCAAGGCAGTTCCAGATGTTTATAGCGTGAAGCGGACCAAT
GGCTAAGAAAGGATAAAAAC

Downstream 100 bases:

>100_bases
TCTCTACAACTAAGAGGTTAGAAAAAAGCAAGCAACTGTTGATAGCGTGTTGCTTGCTTTTTTTGTCAGTTAATCTCATC
ATTTTAGAAGATCGTGGTTA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAYAVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFT
LYADTKKGNRPAFTGAAKPDLASQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH

Sequences:

>Translated_147_residues
MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAYAVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFT
LYADTKKGNRPAFTGAAKPDLASQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH
>Mature_147_residues
MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAYAVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFT
LYADTKKGNRPAFTGAAKPDLASQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=44.5945945945946, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=48.951048951049, Blast_Score=139, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI115533292, Length=149, Percent_Identity=43.6241610738255, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=44.5945945945946, Blast_Score=122, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=41.4965986394558, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 15843; Mature: 15843

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAYAVRKIVNMRIFSDADG
CHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEECCCCC
KMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLASQLYDSFNEQLAEFVPVE
CHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
RGVFGADMQVSLINDGPVTIILDTKCH
CCCCCCCEEEEEECCCCEEEEEECCCC
>Mature Secondary Structure
MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAYAVRKIVNMRIFSDADG
CHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEECCCCC
KMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLASQLYDSFNEQLAEFVPVE
CHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
RGVFGADMQVSLINDGPVTIILDTKCH
CCCCCCCEEEEEECCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8232196; 2989113 [H]