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The map label for this gene is ykuT [H]

Identifier: 15675710

GI number: 15675710

Start: 1573602

End: 1574447

Strand: Direct

Name: ykuT [H]

Synonym: SPy_1897

Alternate gene names: 15675710

Gene position: 1573602-1574447 (Clockwise)

Preceding gene: 15675695

Following gene: 15675717

Centisome position: 84.95

GC content: 34.04

Gene sequence:

>846_bases
ATGACATTTATATTACATTACCTAGAGCAGTCTCATATCGAAAATATTGGCTTAACGATTTTTAAAAAGCTAGTGTCTCT
CATTATTCTATTACTCTTTTTTGCTATTTTAAAACGTGTTACTAACTATCTTTTTGAAAAAACCATTAACAAATCGTTTG
CTTATTCAAGACAAAGTGAAGCTCGCAAAAAAACACTCTCTAAGCTCACTCACAACATTTTAAATTACTTATTATATTTT
CTTCTCATTTATTGGATACTTAGCTTATTTGGCATACCTGTCTCTAGTCTTCTAGCAGGAGCTGGAATTGCTGGAGTAGC
AATCGGGTTAGGTGCACAAGGATTTTTATCTGACGTTGTCAATGGCTTTTTTATCTTATTTGAGAATCAATTTGAAGTAG
GAGATAACGTTACTATCTCTGACATAGAAGGCAGTGTCTTTGGTGTTGGAATTAGAACTACTCAAATTCGTGGATTCGAT
GGAACACTACATTTCATCCCAAACCGTAGCATCACCGTTGTCAGCAACAAATCTCGTGGTAATATGCGTGCCTTAATTGA
AATTCCTCTTTATTCCACTGTTAATTTGAGCCAAGTCACTCGAATCATTGATGAAGTGAATCAAAAGGAATTGCCAAACC
ATCCTCAAATCGTTGGCAAACCAAATATTTTAGGGCCTCAAAATAACTCTAATGGACAGTTCACTTTTAGAATTGCTATT
TTCACAGAAAATGGAGAACAATTTAAGATTTACCATACTTTTTATAGACTTTATCAAGAAGCTTTACTCAAAGAAGGCAT
TCAATTACCGACTGCAATCAGCTATTCTATCACCTCAAAATCTTAA

Upstream 100 bases:

>100_bases
CTTTATGATAAAACAATTATCATAACTTTGGTTAAAATATTAATTTATCTCTTTTCAAGATTGGTTTTTTTTTGATAAAC
TATCAAAGAAAGGATTTCTC

Downstream 100 bases:

>100_bases
TATAATCTTAAAAAATCCTTTTTTCTAGAAAAAACACCAATTGTTTTATTCCAGAAAAAAGGGTTTAGGATTTACGGATA
ATATCCATATTGTAATCAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYLFEKTINKSFAYSRQSEARKKTLSKLTHNILNYLLYF
LLIYWILSLFGIPVSSLLAGAGIAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFD
GTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIVGKPNILGPQNNSNGQFTFRIAI
FTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYSITSKS

Sequences:

>Translated_281_residues
MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYLFEKTINKSFAYSRQSEARKKTLSKLTHNILNYLLYF
LLIYWILSLFGIPVSSLLAGAGIAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFD
GTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIVGKPNILGPQNNSNGQFTFRIAI
FTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYSITSKS
>Mature_280_residues
TFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYLFEKTINKSFAYSRQSEARKKTLSKLTHNILNYLLYFL
LIYWILSLFGIPVSSLLAGAGIAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFDG
TLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIVGKPNILGPQNNSNGQFTFRIAIF
TENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYSITSKS

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=250, Percent_Identity=28.4, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787591, Length=176, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI2367355, Length=207, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 31636; Mature: 31505

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYLFEKTINKSFAYSRQSE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAGIAGVAIGLGAQGFLSDVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHCCCHHHHHHHH
NGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFDGTLHFIPNRSITVVSNKSRG
CCEEEEEECCCCCCCCEEEEECCCCEEEEEEEEEEEECCCCEEEEECCCEEEEEECCCCC
NMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIVGKPNILGPQNNSNGQFTFRIAI
CEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEE
FTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYSITSKS
EECCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
TFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYLFEKTINKSFAYSRQSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAGIAGVAIGLGAQGFLSDVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHCCCHHHHHHHH
NGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFDGTLHFIPNRSITVVSNKSRG
CCEEEEEECCCCCCCCEEEEECCCCEEEEEEEEEEEECCCCEEEEECCCEEEEEECCCCC
NMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIVGKPNILGPQNNSNGQFTFRIAI
CEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEE
FTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYSITSKS
EECCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]