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The map label for this gene is ftsZ [H]

Identifier: 15675420

GI number: 15675420

Start: 1248393

End: 1249712

Strand: Reverse

Name: ftsZ [H]

Synonym: SPy_1520

Alternate gene names: 15675420

Gene position: 1249712-1248393 (Counterclockwise)

Preceding gene: 15675421

Following gene: 15675419

Centisome position: 67.46

GC content: 42.42

Gene sequence:

>1320_bases
ATGGCATTTTCATTTGATACTGCATCAATTCAAGGTGCAATTATAAAAGTAATTGGAGTCGGCGGAGGTGGCGGAAATGC
CATTAATCGTATGATTGATGAAGGTGTTGCTGGTGTCGAGTTCATCGCAGCAAACACAGACATTCAGGCATTAAGCTCAT
CAAAAGCTGAAACGGTTATTCAACTAGGCCCTAAATTAACTCGTGGACTTGGTGCTGGAGGACAACCTGAAGTAGGACGT
AAAGCTGCTGAAGAAAGCGAAGAAATTTTAACAGAAGCTCTTACAGGAGCGGACATGGTATTTATTACTGCCGGTATGGG
TGGTGGCTCTGGGACAGGGGCTGCACCGGTTATTGCTCGTATCGCTAAAAGTTTGGGAGCCTTGACAGTAGCTGTTGTTA
CTCGCCCGTTTGGTTTTGAAGGTAACAAACGTGGTAATTTTGCTATTGAAGGTATCGAAGAACTACGTGAACAAGTTGAT
ACTTTGTTAATTATTTCAAATAATAACCTTCTTGAGATTGTTGATAAAAAGACACCTTTATTAGAAGCACTTAGTGAAGC
TGATAATGTTTTACGCCAGGGAGTTCAAGGGATAACCGACTTAATTACTAGTCCTGGCCTTATCAATCTCGATTTTGCCG
ACGTGAAAACAGTTATGGCAAATAAAGGGAATGCCTTGATGGGGATTGGGATTGGCTCTGGAGAAGAGCGCATTGTTGAG
GCGGCGCGTAAGGCAATCTATTCACCCCTATTAGAAACGACTATTGATGGTGCACAAGACGTTATTGTGAACGTTACAGG
AGGTCTCGACATGACACTTACAGAAGCTGAAGAAGCCTCTGAAATTGTTGGGCAAGCTGCTGGTCAAGGCGTTAACATTT
GGTTAGGAACATCTATTGATGATACTATGAAAGATGACATCCGTGTGACTGTTGTAGCAACTGGAGTGCGCCAAGAAAAA
GCCGAACAAGTTTCAGGTTTTCGTCAGCCTAGGACTTTTACCCAAACCAACGCGCAGCAAGTAGCGGGTGCACAATATGC
ATCAGATCAAGCAAAACAGTCGGTTCAACCAGGGTTTGATCGTCGCTCAAATTTTGATTTTGACATGGGGGAGTCTCGCG
AGATACCAAGTGCACAAAAGGTAATTTCTAATCATAATCAAAATCAAGGTTCTGCTTTTGGAAATTGGGATTTGAGACGT
GATAATATTTCTCGTCCAACAGAAGGTGAATTGGATAACCATCTTAATATGTCAACGTTCTCAGCTAACGATGACAGTGA
TGATGAATTAGAAACGCCTCCATTCTTTAAAAACCGTTAA

Upstream 100 bases:

>100_bases
ATTCACAAGTTCCGAGTGATCCTAAACAAAAAATTTCAGAACGTGTTCGTGGCATATTTGGGAGTATGTTTGATTAAAAG
TAATAAAGTGAGGAAATAAA

Downstream 100 bases:

>100_bases
TAATGGATTTACTGACAAATAAAAAGAAAATTTTTGAGACTATCCGCTTATCTACAGAGGCAGCAAATAGGACTAATGAT
AGTGTTTCAGTTATTGCTGT

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAANTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGR
KAAEESEEILTEALTGADMVFITAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVD
TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTVMANKGNALMGIGIGSGEERIVE
AARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEAEEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEK
AEQVSGFRQPRTFTQTNAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSAFGNWDLRR
DNISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR

Sequences:

>Translated_439_residues
MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAANTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGR
KAAEESEEILTEALTGADMVFITAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVD
TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTVMANKGNALMGIGIGSGEERIVE
AARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEAEEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEK
AEQVSGFRQPRTFTQTNAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSAFGNWDLRR
DNISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR
>Mature_438_residues
AFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAANTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRK
AAEESEEILTEALTGADMVFITAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVDT
LLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTVMANKGNALMGIGIGSGEERIVEA
ARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEAEEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEKA
EQVSGFRQPRTFTQTNAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSAFGNWDLRRD
NISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=301, Percent_Identity=52.4916943521595, Blast_Score=275, Evalue=4e-75,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 46432; Mature: 46301

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS01134 FTSZ_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAANTDIQALSSSKAETVI
CCCCCCCCHHCCEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHCCHHHHHH
QLGPKLTRGLGAGGQPEVGRKAAEESEEILTEALTGADMVFITAGMGGGSGTGAAPVIAR
HHCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHH
IAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVDTLLIISNNNLLEIVDKKTPL
HHHHHHHEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHCEEEEECCCCEEEEECCCCHH
LEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTVMANKGNALMGIGIGSGEERIVE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCEEEEEECCCCHHHHHH
AARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEAEEASEIVGQAAGQGVNIWLGTSID
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCEEEEECCCCC
DTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFTQTNAQQVAGAQYASDQAKQSVQPGFD
CCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCC
RRSNFDFDMGESREIPSAQKVISNHNQNQGSAFGNWDLRRDNISRPTEGELDNHLNMSTF
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
SANDDSDDELETPPFFKNR
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAANTDIQALSSSKAETVI
CCCCCCCHHCCEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHCCHHHHHH
QLGPKLTRGLGAGGQPEVGRKAAEESEEILTEALTGADMVFITAGMGGGSGTGAAPVIAR
HHCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHH
IAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVDTLLIISNNNLLEIVDKKTPL
HHHHHHHEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHCEEEEECCCCEEEEECCCCHH
LEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTVMANKGNALMGIGIGSGEERIVE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCEEEEEECCCCHHHHHH
AARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEAEEASEIVGQAAGQGVNIWLGTSID
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCEEEEECCCCC
DTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFTQTNAQQVAGAQYASDQAKQSVQPGFD
CCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCC
RRSNFDFDMGESREIPSAQKVISNHNQNQGSAFGNWDLRRDNISRPTEGELDNHLNMSTF
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
SANDDSDDELETPPFFKNR
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9287029; 12663927 [H]