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The map label for this gene is fps [H]

Identifier: 15675402

GI number: 15675402

Start: 1229551

End: 1230423

Strand: Reverse

Name: fps [H]

Synonym: SPy_1498

Alternate gene names: 15675402

Gene position: 1230423-1229551 (Counterclockwise)

Preceding gene: 15675403

Following gene: 15675401

Centisome position: 66.42

GC content: 41.01

Gene sequence:

>873_bases
ATGGACAAATTAGCTAGAATTGACGAAGCCATTCGTCGCTACTATAAGACGACTAGTAACGGTGTATCTGAAGAGTTGAT
TGATGCTATCTTGTATTCTGTTGACAGTGGTGGCAAGCGCATTCGCCCACTTATCTTATTAGAGATGATTGAGGGATTTG
GGGTATCGTTACAGAATGCTCATTTTGATTTGGCTGCAGCTCTTGAAATGATTCATACAGGAAGTCTGATTCACGATGAT
TTGCCAGCCATGGATAATGATGATTACCGACGTGGCAGACTGACCAATCACAAACAATTTGGAGAAGCCACGGCCATTTT
GGCGGGAGACAGCTTATTTTTAGACCCCTTTGGGTTAATAGCTCAAGCTGAATTAAATAGTGAGGTTAAAGTAGCCTTAA
TCCAAGAACTTTCCCTAGCTTCAGGAACTTTTGGCATGGTTGGTGGTCAGATGTTAGATATGAAAGGGGAAAATCAAGCA
TTAAGTCTTCCTCAGTTGTCACTGATTCACCTCAATAAAACCGGAAAATTATTAGCTTTTCCTTTTAAAGCAGCAGCTCT
TATAACAGAACAGGCTATGACTGTTCGTCAACAACTAGAGCAAGCGGGAATGCTCATCGGGCACGCCTTTCAGATTAGGG
ATGATATTTTAGACGTGACAGCTAGCTTTGAAGATCTTGGAAAAACGCCTAAAAAGGACTTATTCGCAGAAAAAGCTACT
TATCCAAGTTTACTGGGGTTAGAAGCCTCTTACCAACTGCTGACAGAGAGTTTAGATCAGGCTTTGACGATTTTTCAGAC
ACTAGAAAGCGATGTAGGCTTTAAGCCTCAAATAATTACAAAACTGATAGAAGGGTTACGACTTAATGCCTAA

Upstream 100 bases:

>100_bases
TGCTTCTCTCAAAAGAACTTCAAAAGACCTTACAAGCGGCAGAAAAAACACTCGTCAAAGTGATGCAAGCTGATGGCACA
GAAGTAGATATGGATGATTA

Downstream 100 bases:

>100_bases
AGAAAGAGTAGATGTGTTAGCCTATAAGCAAGGATTATTTGAGACCAGAGAGCAAGCTAAGCGTGGTGTCATGGCAGGCT
TAGTGGTCTCTGTGATTAAT

Product: putative geranyltranstransferase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPLILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDD
LPAMDNDDYRRGRLTNHKQFGEATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
LSLPQLSLIHLNKTGKLLAFPFKAAALITEQAMTVRQQLEQAGMLIGHAFQIRDDILDVTASFEDLGKTPKKDLFAEKAT
YPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKPQIITKLIEGLRLNA

Sequences:

>Translated_290_residues
MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPLILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDD
LPAMDNDDYRRGRLTNHKQFGEATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
LSLPQLSLIHLNKTGKLLAFPFKAAALITEQAMTVRQQLEQAGMLIGHAFQIRDDILDVTASFEDLGKTPKKDLFAEKAT
YPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKPQIITKLIEGLRLNA
>Mature_290_residues
MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPLILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDD
LPAMDNDDYRRGRLTNHKQFGEATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
LSLPQLSLIHLNKTGKLLAFPFKAAALITEQAMTVRQQLEQAGMLIGHAFQIRDDILDVTASFEDLGKTPKKDLFAEKAT
YPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKPQIITKLIEGLRLNA

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=234, Percent_Identity=30.7692307692308, Blast_Score=88, Evalue=8e-18,
Organism=Escherichia coli, GI1786623, Length=243, Percent_Identity=42.3868312757202, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789578, Length=215, Percent_Identity=30.6976744186047, Blast_Score=96, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24651612, Length=262, Percent_Identity=30.9160305343511, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 31825; Mature: 31825

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPLILLEMIEGFGVSLQNA
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCC
HFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGEATAILAGDSLFLDPFGLI
HHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCHHHCCEEEEEECCCEEECCHHHH
AQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQALSLPQLSLIHLNKTGKLLAF
HHHCCCCCHHHHHHHHHHHCCCCHHHCCCEEEECCCCCCEECCCCEEEEEECCCCCEEEE
PFKAAALITEQAMTVRQQLEQAGMLIGHAFQIRDDILDVTASFEDLGKTPKKDLFAEKAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHCC
YPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKPQIITKLIEGLRLNA
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPLILLEMIEGFGVSLQNA
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCC
HFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGEATAILAGDSLFLDPFGLI
HHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCHHHCCEEEEEECCCEEECCHHHH
AQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQALSLPQLSLIHLNKTGKLLAF
HHHCCCCCHHHHHHHHHHHCCCCHHHCCCEEEECCCCCCEECCCCEEEEEECCCCCEEEE
PFKAAALITEQAMTVRQQLEQAGMLIGHAFQIRDDILDVTASFEDLGKTPKKDLFAEKAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHCC
YPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKPQIITKLIEGLRLNA
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515931 [H]